PE anti-mouse CD49d | BioLegend 103608 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse CD49d

catalog :

103608

quantity :

200 μg

price :

297 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

R1-2

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Reference
Cagle L, Linderholm A, Franzi L, Last J, Simon S, Kenyon N, et al. Early mechanisms of neutrophil activation and transmigration in acute lung injury. Front Physiol. 2022;13:1059686 pubmed publisher
Hamdi L, Nabat H, Goldberg Y, Fainstein N, Segal S, Mediouni E, et al. Exercise training alters autoimmune cell invasion into the brain in autoimmune encephalomyelitis. Ann Clin Transl Neurol. 2022;9:1792-1806 pubmed publisher
Dhalech A, Corn C, Mangale V, Syed F, Condotta S, Richer M, et al. Testosterone Promotes the Intestinal Replication and Dissemination of Coxsackievirus B3 in an Oral Inoculation Mouse Model. J Virol. 2022;96:e0123222 pubmed publisher
Doughty D, Rajpurohit S, Trang A, Alptekin A, Korkaya A, Achyut B, et al. Development of a novel purification protocol to isolate and identify brain microglia. Exp Biol Med (Maywood). 2022;247:1433-1446 pubmed publisher
Pardy R, Valbon S, Cordeiro B, Krawczyk C, Richer M. An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways. Nat Commun. 2021;12:4051 pubmed publisher
Jiang X, Prabhakar A, van der Voorn S, Ghatpande P, Celona B, Venkataramanan S, et al. Control of ribosomal protein synthesis by the Microprocessor complex. Sci Signal. 2021;14: pubmed publisher
Waide M, Polidoro R, Powell W, Denny J, Kos J, Tieri D, et al. Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections. Cell Rep. 2020;33:108503 pubmed publisher
Riedel R, Addo R, Ferreira Gomes M, Heinz G, Heinrich F, Kummer J, et al. Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nat Commun. 2020;11:2570 pubmed publisher
Horiguchi H, Kadomatsu T, Kurahashi R, Hara C, Miyata K, Baba M, et al. Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity. Genes Dev. 2019;33:1641-1656 pubmed publisher
Pietronigro E, Zenaro E, Bianca V, Dusi S, Terrabuio E, Iannoto G, et al. Blockade of α4 integrins reduces leukocyte-endothelial interactions in cerebral vessels and improves memory in a mouse model of Alzheimer's disease. Sci Rep. 2019;9:12055 pubmed publisher
Gaylo Moynihan A, Prizant H, Popovic M, Fernandes N, Anderson C, Chiou K, et al. Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites. Immunity. 2019;51:298-309.e6 pubmed publisher
Hernández Santos N, Wiesner D, Fites J, McDermott A, Warner T, Wuthrich M, et al. Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection. Cell Host Microbe. 2018;23:511-522.e5 pubmed publisher
Foster G, Xu L, Chidambaram A, Soderberg S, Armstrong E, Wu H, et al. CD11c/CD18 Signals Very Late Antigen-4 Activation To Initiate Foamy Monocyte Recruitment during the Onset of Hypercholesterolemia. J Immunol. 2015;195:5380-92 pubmed publisher
Toda S, Segawa K, Nagata S. MerTK-mediated engulfment of pyrenocytes by central macrophages in erythroblastic islands. Blood. 2014;123:3963-71 pubmed publisher

product information

Antigen :

CD49d

Apps. Abbrev. :

Cat # :

103608

Clone :

R1-2

Item :

PE anti-mouse CD49d

Isotype :

Rat IgG2b, κ

Other Names :

α4 integrin, VLA-4 α chain, integrin α4, ITGA4

Size :

200 μg

Price (USD) :

297 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

AKR/Cum mouse spontaneous T lymphoma line TK1

Application Notes :

The R1-2 antibody has been shown to partially block CD49d mediated interactions and, in combination with the 9C10 (MFR4.B) antibody, completely blocks VCAM-1 binding to VLA-4. Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of cell-cell adhesion and T cell costimulation^1-4, immunoprecipitation^1, and immunohistochemistry of frozen sections^5. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103629 and 103630;).;

more info or order :

BioLegend product webpage