This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 594 anti-mouse CD48
catalog :
103436
quantity :
100 μg
price :
292 USD
clonality :
monoclonal
host :
hamsters
conjugate :
Alexa Fluor 594
clone name :
HM48-1
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100
Castiello M, Bosticardo M, Sacchetti N, Calzoni E, Fontana E, Yamazaki Y, et al. Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency. J Allergy Clin Immunol. 2021;147:309-320.e6 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s9i
Uckelmann H, Kim S, Wong E, Hatton C, Giovinazzo H, Gadrey J, et al. Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia. Science. 2020;367:586-590 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig ex9j
Tikhonova A, Dolgalev I, Hu H, Sivaraj K, Hoxha E, Cuesta Dominguez A, et al. The bone marrow microenvironment at single-cell resolution. Nature. 2019;569:222-228 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5b
Umemoto T, Hashimoto M, Matsumura T, Nakamura Ishizu A, Suda T. Ca2+-mitochondria axis drives cell division in hematopoietic stem cells. J Exp Med. 2018;215:2097-2113 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Kurkewich J, Boucher A, Klopfenstein N, Baskar R, Kapur R, Dahl R. The mirn23a and mirn23b microrna clusters are necessary for proper hematopoietic progenitor cell production and differentiation. Exp Hematol. 2018;59:14-29 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Wallrapp A, Riesenfeld S, Burkett P, Abdulnour R, Nyman J, Dionne D, et al. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. 2017;549:351-356 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Kurkewich J, Bikorimana E, Nguyen T, Klopfenstein N, Zhang H, Hallas W, et al. The mirn23a microRNA cluster antagonizes B cell development. J Leukoc Biol. 2016;100:665-677 pubmed
  • flow cytometry; mouse; loading ...; fig 1a
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
B guelin W, Teater M, Meydan C, Hoehn K, Phillip J, Soshnev A, et al. Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response. Cancer Cell. 2020;37:655-673.e11 pubmed publisher
Rao T, Gupta M, Softic S, Wang L, Jang Y, Thomou T, et al. Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors. EMBO J. 2018;37: pubmed publisher
Upadhaya S, Sawai C, Papalexi E, Rashidfarrokhi A, Jang G, Chattopadhyay P, et al. Kinetics of adult hematopoietic stem cell differentiation in vivo. J Exp Med. 2018;215:2815-2832 pubmed publisher
Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed publisher
Bellelli R, Borel V, Logan C, Svendsen J, Cox D, Nye E, et al. Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Mol Cell. 2018;70:707-721.e7 pubmed publisher
Huo Y, Li B, Lin Z, Wang W, Jiang X, Chen X, et al. MYSM1 Is Essential for Maintaining Hematopoietic Stem Cell (HSC) Quiescence and Survival. Med Sci Monit. 2018;24:2541-2549 pubmed
Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, et al. SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling. J Exp Med. 2018;215:1337-1347 pubmed publisher
Verbiest T, Finnon R, Brown N, Cruz Garcia L, Finnon P, O Brien G, et al. Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis. Leukemia. 2018;32:1435-1444 pubmed publisher
Zhang H, Li H, Hillmer E, Zhao Y, Chrisikos T, Hu H, et al. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proc Natl Acad Sci U S A. 2018;115:E2311-E2319 pubmed publisher
Chapple R, Hu T, Tseng Y, Liu L, Kitano A, Luu V, et al. ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response. elife. 2018;7: pubmed publisher
McKenney A, Lau A, Somasundara A, Spitzer B, Intlekofer A, Ahn J, et al. JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. J Clin Invest. 2018;128:789-804 pubmed publisher
Singh P, Hoggatt J, Kamocka M, Mohammad K, Saunders M, Li H, et al. Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells. J Clin Invest. 2017;127:4527-4540 pubmed publisher
Umemoto T, Matsuzaki Y, Shiratsuchi Y, Hashimoto M, Yoshimoto T, Nakamura Ishizu A, et al. Integrin αvβ3 enhances the suppressive effect of interferon-γ on hematopoietic stem cells. EMBO J. 2017;36:2390-2403 pubmed publisher
Xu C, Lee T, Sakurai N, Krchma K, Liu F, Li D, et al. ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation. J Exp Med. 2017;214:1643-1653 pubmed publisher
Kramer A, Kothari A, Wilson W, Celik H, Nikitas J, Mallaney C, et al. Dnmt3a regulates T-cell development and suppresses T-ALL transformation. Leukemia. 2017;31:2479-2490 pubmed publisher
product information
Antigen :
CD48
Apps. Abbrev. :
IHC-F
Cat # :
103436
Clone :
HM48-1
Item :
Alexa Fluor® 594 anti-mouse CD48
Isotype :
Armenian Hamster IgG
Other Names :
BCM1, SLAMF2, Blast-1
Size :
100 μg
Price (USD) :
292 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
A594
Immunogen :
Mouse T lymphoma MBL-2
Application Notes :
The HM48-1 antibody is useful for blocking in vitro and in vivo CD48 mediated interactions. Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , costimulation of T cell proliferation 1,2 , blocking of CD48-CD2 interaction 1 , and inhibition of CTL activity and graft rejection 1,2 . For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. Nos. 103452-103456) with a lower endotoxin limit (Endotoxin 0.01 EU/ug).
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA