product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-mouse CD48
catalog :
103432
quantity :
100 μg
price :
347 USD
clonality :
monoclonal
host :
hamsters
conjugate :
APC/Cy7
clone name :
HM48-1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 39
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 1a
Mitroulis I, Ruppova K, Wang B, Chen L, Grzybek M, Grinenko T, et al. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. 2018;172:147-161.e12 pubmed publisher
  • flow cytometry; mouse
Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed publisher
van Os B, Kusters P, den Toom M, Beckers L, Van Tiel C, Vos W, et al. Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis. Front Cardiovasc Med. 2023;10:1171764 pubmed publisher
Hu R, Liang J, Ding L, Zhang W, Wang Y, Zhang Y, et al. Gasdermin D inhibition ameliorates neutrophil mediated brain damage in acute ischemic stroke. Cell Death Discov. 2023;9:50 pubmed publisher
Yoshida K, Satoh Y, Uchimura A, Misumi M, Kyoizumi S, Taga M, et al. Massive expansion of multiple clones in the mouse hematopoietic system long after whole-body X-irradiation. Sci Rep. 2022;12:17276 pubmed publisher
Yang T, Ou J, Yildirim E. Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis. Nat Commun. 2022;13:4464 pubmed publisher
Kinkel S, Liu J, Beck T, Breslin K, Iminitoff M, Hickey P, et al. Epigenetic modifier SMCHD1 maintains a normal pool of long-term hematopoietic stem cells. iScience. 2022;25:104684 pubmed publisher
Ramdas B, Yuen L, Palam L, Patel R, Pasupuleti S, Jideonwo V, et al. Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells. Mol Ther. 2022;30:2505-2521 pubmed publisher
Yang S, Sun G, Wu P, Chen C, Kuang Y, Liu L, et al. WDR82-binding long noncoding RNA lncEry controls mouse erythroid differentiation and maturation. J Exp Med. 2022;219: pubmed publisher
Li C, Zhang G, Du J, Liu D, Li Z, Ni Y, et al. Pre-configuring chromatin architecture with histone modifications guides hematopoietic stem cell formation in mouse embryos. Nat Commun. 2022;13:346 pubmed publisher
Brandi P, Conejero L, Cueto F, Mart xed nez Cano S, Dunphy G, G xf3 mez M, et al. Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections. Cell Rep. 2022;38:110184 pubmed publisher
Sohn J, Milosević J, Brouse T, Aziz N, Elkhoury J, Wang S, et al. A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis. Blood Adv. 2022;6:2557-2577 pubmed publisher
Mistry J, Hellmich C, Moore J, Jibril A, Macaulay I, Moreno Gonzalez M, et al. Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection. Nat Commun. 2021;12:7130 pubmed publisher
Young I, Wu B, Andricovich J, Chuang S, Li R, Tzatsos A, et al. Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling. Cell Rep. 2021;37:110036 pubmed publisher
Pessoa Rodrigues C, Akhtar A. Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells. Sci Adv. 2021;7: pubmed publisher
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher
Lv K, Gong C, Antony C, Han X, Ren J, Donaghy R, et al. HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis. Cell Stem Cell. 2021;28:1275-1290.e9 pubmed publisher
Montel Hagen A, Sun V, Casero D, Tsai S, Zampieri A, Jackson N, et al. In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells. Cell Rep. 2020;33:108320 pubmed publisher
Naka K, Ochiai R, Matsubara E, Kondo C, Yang K, Hoshii T, et al. The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells. Nat Commun. 2020;11:4681 pubmed publisher
De Koninck M, Lapi E, Badia Careaga C, Cossío I, Giménez Llorente D, Rodríguez Corsino M, et al. Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis. Cell Rep. 2020;32:108014 pubmed publisher
Tran N, Trombke J, Rajewsky K, Chu V. Protocol for Efficient CRISPR/Cas9/AAV-Mediated Homologous Recombination in Mouse Hematopoietic Stem and Progenitor Cells. STAR Protoc. 2020;1:100028 pubmed publisher
Pessoa Rodrigues C, Herman J, Herquel B, Valsecchi C, Stehle T, Grün D, et al. Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Sci Adv. 2020;6:eaaz4815 pubmed publisher
Siamishi I, Iwanami N, Clapes T, Trompouki E, O Meara C, Boehm T. Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Rep. 2020;31:107756 pubmed publisher
Sztwiertnia I, Schenz J, Bomans K, Schaack D, Ohnesorge J, Tamulyte S, et al. Sevoflurane depletes macrophages from the melanoma microenvironment. PLoS ONE. 2020;15:e0233789 pubmed publisher
Morales Torres C, Wu M, Hobor S, Wainwright E, Martin M, Patel H, et al. Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nat Commun. 2020;11:1792 pubmed publisher
Paubelle E, Zylbersztejn F, Maciel T, Carvalho C, Mupo A, Cheok M, et al. Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow. Cell Rep. 2020;30:739-754.e4 pubmed publisher
Giannini S, Lee Sundlov M, Rivadeneyra L, Di Buduo C, Burns R, Lau J, et al. β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis. Nat Commun. 2020;11:356 pubmed publisher
Aegerter H, Kulikauskaite J, Crotta S, Patel H, Kelly G, Hessel E, et al. Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection. Nat Immunol. 2020;21:145-157 pubmed publisher
Fukushima T, Tanaka Y, Hamey F, Chang C, Oki T, Asada S, et al. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019;29:4144-4158.e7 pubmed publisher
Tran N, Sommermann T, Graf R, Trombke J, Pempe J, Petsch K, et al. Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells. Cell Rep. 2019;28:3510-3522.e5 pubmed publisher
Severe N, Karabacak N, Gustafsson K, Baryawno N, Courties G, Kfoury Y, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25:570-583.e7 pubmed publisher
Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez R, Taguchi T, et al. LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. Cell Metab. 2019;: pubmed publisher
Yoshida H, Lareau C, Ramirez R, Rose S, Maier B, Wroblewska A, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019;176:897-912.e20 pubmed publisher
Yamamoto R, Wilkinson A, Ooehara J, Lan X, Lai C, Nakauchi Y, et al. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. Cell Stem Cell. 2018;22:600-607.e4 pubmed publisher
Passaro D, di Tullio A, Abarrategi A, Rouault Pierre K, Foster K, Ariza McNaughton L, et al. Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia. Cancer Cell. 2017;32:324-341.e6 pubmed publisher
Mooney C, Cunningham A, Tsapogas P, Toellner K, Brown G. Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment. Int J Mol Sci. 2017;18: pubmed publisher
Schneider R, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, van Strien P, et al. Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 2017;20:785-800.e8 pubmed publisher
Sykes D, Kfoury Y, Mercier F, Wawer M, Law J, Haynes M, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. 2016;167:171-186.e15 pubmed publisher
Naka K, Jomen Y, Ishihara K, Kim J, Ishimoto T, Bae E, et al. Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells. Nat Commun. 2015;6:8039 pubmed publisher
product information
Antigen :
CD48
Apps. Abbrev. :
FC
Cat # :
103432
Clone :
HM48-1
Item :
APC/Cyanine7 anti-mouse CD48
Isotype :
Armenian Hamster IgG
Other Names :
BCM1, SLAMF2, Blast-1
Size :
100 μg
Price (USD) :
347 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
APC_CYANINE7
Immunogen :
Mouse T lymphoma MBL-2
Application Notes :
The HM48-1 antibody is useful for blocking in vitro and in vivo CD48 mediated interactions. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, costimulation of T cell proliferation^1,2, blocking of CD48-CD2 interaction^1, and inhibition of CTL activity and graft rejection^1,2. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. Nos. 103452-103456) with a lower endotoxin limit (Endotoxin < 0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA