product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-mouse CD45
catalog :
103114
quantity :
100 μg
price :
190 USD
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
30-F11
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 132
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1
Kawakubo A, Miyagi M, Yokozeki Y, Nakawaki M, Takano S, Satoh M, et al. Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model. Int J Immunopathol Pharmacol. 2022;36:3946320221103792 pubmed publisher
  • flow cytometry; mouse; 1:100; fig 2a
Khan I, Del Guzzo C, Shao A, Cho J, Du R, Cohen A, et al. The CD200-CD200R Axis Promotes Squamous Cell Carcinoma Metastasis via Regulation of Cathepsin K. Cancer Res. 2021;81:5021-5032 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Nakajima S, Tanaka R, Yamashiro K, Chiba A, Noto D, Inaba T, et al. Mucosal-Associated Invariant T Cells Are Involved in Acute Ischemic Stroke by Regulating Neuroinflammation. J Am Heart Assoc. 2021;10:e018803 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 8a, 9a
Mao F, Lv Y, Hao C, Teng Y, Liu Y, Cheng P, et al. Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense. Cell Mol Gastroenterol Hepatol. 2021;12:395-425 pubmed publisher
  • flow cytometry; mouse; 1:250; fig 5f
Kharkwal S, Johndrow C, Veerapen N, Kharkwal H, Saavedra Avila N, Carreño L, et al. Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T-cell Engagers Generates Antitumor Immunity While Avoiding Anergy. Cancer Res. 2021;81:1788-1801 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s6m
Uezumi A, Ikemoto Uezumi M, Zhou H, Kurosawa T, Yoshimoto Y, Nakatani M, et al. Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia. J Clin Invest. 2021;131: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a, s4e
Thiele Née Schrewe L, Guse K, Tietz S, Remlinger J, Demir S, Pedreiturria X, et al. Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis. J Neuroinflammation. 2020;17:9 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2f
Hurrell B, Galle Treger L, Jahani P, Howard E, Helou D, Banie H, et al. TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity. Cell Rep. 2019;29:4509-4524.e5 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 6s1
Lavoie S, Conway K, Lassen K, Jijon H, Pan H, Chun E, et al. The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Lund H, Pieber M, Parsa R, Han J, Grommisch D, Ewing E, et al. Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells. Nat Commun. 2018;9:4845 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Wheeler D, Sariol A, Meyerholz D, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. J Clin Invest. 2018;128:931-943 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Ireland L, Santos A, Campbell F, Figueiredo C, Hammond D, Ellies L, et al. Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer. Oncogene. 2018;37:2022-2036 pubmed publisher
  • flow cytometry; mouse
Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6b
Weeden C, Chen Y, Ma S, Hu Y, Ramm G, Sutherland K, et al. Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway. PLoS Biol. 2017;15:e2000731 pubmed publisher
  • flow cytometry; mouse; fig 3
Jaworska K, Ratajczak J, Huang L, Whalen K, Yang M, Stevens B, et al. Both PD-1 ligands protect the kidney from ischemia reperfusion injury. J Immunol. 2015;194:325-33 pubmed publisher
  • flow cytometry; mouse
Sousa Victor P, Gutarra S, García Prat L, Rodriguez Ubreva J, Ortet L, Ruiz Bonilla V, et al. Geriatric muscle stem cells switch reversible quiescence into senescence. Nature. 2014;506:316-21 pubmed publisher
  • flow cytometry; mouse
Makarem M, Kannan N, Nguyen L, Knapp D, Balani S, Prater M, et al. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells. PLoS Biol. 2013;11:e1001630 pubmed publisher
Berg A, Rowson Hodel A, Hu M, KEELING M, Wu H, VanderVorst K, et al. The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies. Cancers (Basel). 2022;14: pubmed publisher
Li Q, Zhong X, Yao W, Yu J, Wang C, Li Z, et al. Inhibitor of glutamine metabolism V9302 promotes ROS-induced autophagic degradation of B7H3 to enhance antitumor immunity. J Biol Chem. 2022;298:101753 pubmed publisher
Leary N, Walser S, He Y, Cousin N, Pereira P, Gallo A, et al. Melanoma-derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes. J Extracell Vesicles. 2022;11:e12197 pubmed publisher
Manivasagam S, Williams J, Vollmer L, Bollman B, Bartleson J, Ai S, et al. Targeting IFN-λ Signaling Promotes Recovery from Central Nervous System Autoimmunity. J Immunol. 2022;208:1341-1351 pubmed publisher
Yuan M, Zhai Y, Men Y, Zhao M, Sun X, Ma Z, et al. Anlotinib Enhances the Antitumor Activity of High-Dose Irradiation Combined with Anti-PD-L1 by Potentiating the Tumor Immune Microenvironment in Murine Lung Cancer. Oxid Med Cell Longev. 2022;2022:5479491 pubmed publisher
Abdelfattah N, Kumar P, Wang C, Leu J, Flynn W, Gao R, et al. Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. Nat Commun. 2022;13:767 pubmed publisher
Dong H, Sun W, Shen Y, Balaz M, Balazova L, Ding L, et al. Identification of a regulatory pathway inhibiting adipogenesis via RSPO2. Nat Metab. 2022;4:90-105 pubmed publisher
Hakim R, Zachariadis V, Sankavaram S, Han J, Harris R, Brundin L, et al. Spinal Cord Injury Induces Permanent Reprogramming of Microglia into a Disease-Associated State Which Contributes to Functional Recovery. J Neurosci. 2021;41:8441-8459 pubmed publisher
Yokozeki Y, Kawakubo A, Miyagi M, Kuroda A, Sekiguchi H, Inoue G, et al. Reduced TGF-β Expression and CD206-Positive Resident Macrophages in the Intervertebral Discs of Aged Mice. Biomed Res Int. 2021;2021:7988320 pubmed publisher
Okubo K, Brenner M, Cullere X, Saggu G, Patchen M, Bose N, et al. Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling. Cell Rep. 2021;35:109142 pubmed publisher
Dell Orso S, Juan A, Moiseeva V, García Prat L, Munoz Canoves P, Sartorelli V. Protocol for RNA-seq library preparation starting from a rare muscle stem cell population or a limited number of mouse embryonic stem cells. STAR Protoc. 2021;2:100451 pubmed publisher
Kimmel J, Yi N, Roy M, Hendrickson D, Kelley D. Differentiation reveals latent features of aging and an energy barrier in murine myogenesis. Cell Rep. 2021;35:109046 pubmed publisher
Valdes Mora F, Salomon R, Gloss B, Law A, Venhuizen J, Castillo L, et al. Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype. Cell Rep. 2021;35:108945 pubmed publisher
Sheng J, Chen Q, Wu X, Dong Y, Mayer J, Zhang J, et al. Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population. elife. 2021;10: pubmed publisher
Andreou T, Williams J, Brownlie R, Salmond R, Watson E, Shaw G, et al. Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model. J Immunother Cancer. 2021;9: pubmed publisher
Deerhake M, Danzaki K, Inoue M, Cardakli E, Nonaka T, Aggarwal N, et al. Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M. Immunity. 2021;54:484-498.e8 pubmed publisher
Wang F, Trier A, Li F, Kim S, Chen Z, Chai J, et al. A basophil-neuronal axis promotes itch. Cell. 2021;184:422-440.e17 pubmed publisher
Huang C, Mendez N, Echeagaray O, Weeks J, Wang J, Yao S, et al. Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy. Adv Ther (Weinh). 2020;3: pubmed publisher
Fennell L, Gómez Diaz C, Deszcz L, Kavirayani A, Hoffmann D, Yanagitani K, et al. Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. EMBO J. 2020;:e103303 pubmed publisher
Ognjenovic N, Bagheri M, Mohamed G, Xu K, Chen Y, Mohamed Saleem M, et al. Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors. Dev Cell. 2020;55:544-557.e6 pubmed publisher
Kobayashi H, Takubo K. Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells. STAR Protoc. 2020;1:100078 pubmed publisher
Kolodziejczyk A, Federici S, Zmora N, Mohapatra G, Dori Bachash M, Hornstein S, et al. Acute liver failure is regulated by MYC- and microbiome-dependent programs. Nat Med. 2020;26:1899-1911 pubmed publisher
Hering L, Katkeviciute E, Schwarzfischer M, Busenhart P, Gottier C, Mrdjen D, et al. Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance. Front Immunol. 2020;11:1856 pubmed publisher
Cassidy B, Zhang M, Sonntag W, Drevets D. Neuroinvasive Listeria monocytogenes infection triggers accumulation of brain CD8+ tissue-resident memory T cells in a miR-155-dependent fashion. J Neuroinflammation. 2020;17:259 pubmed publisher
Hasegawa T, Kikuta J, Sudo T, Yamashita E, Seno S, Takeuchi T, et al. Development of an intravital imaging system for the synovial tissue reveals the dynamics of CTLA-4 Ig in vivo. Sci Rep. 2020;10:13480 pubmed publisher
van Gastel N, Spinelli J, Sharda A, Schajnovitz A, Baryawno N, Rhee C, et al. Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance. Cell Metab. 2020;32:391-403.e6 pubmed publisher
Gomzikova M, Aimaletdinov A, Bondar O, Starostina I, Gorshkova N, Neustroeva O, et al. Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells. Sci Rep. 2020;10:10740 pubmed publisher
Evgin L, Huff A, Wongthida P, Thompson J, Kottke T, Tonne J, et al. Oncolytic virus-derived type I interferon restricts CAR T cell therapy. Nat Commun. 2020;11:3187 pubmed publisher
Cain M, Hernandez B, Chen J. Quantitative single-cell interactomes in normal and virus-infected mouse lungs. Dis Model Mech. 2020;13: pubmed publisher
Gerner Mauro K, Akiyama H, Chen J. Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors. Proc Natl Acad Sci U S A. 2020;117:12182-12191 pubmed publisher
Shi Y, Kang X, Wang Y, Bian X, He G, Zhou M, et al. Exosomes Derived from Bone Marrow Stromal Cells (BMSCs) Enhance Tendon-Bone Healing by Regulating Macrophage Polarization. Med Sci Monit. 2020;26:e923328 pubmed publisher
Bahar Halpern K, Massalha H, Zwick R, Moor A, Castillo Azofeifa D, Rozenberg M, et al. Lgr5+ telocytes are a signaling source at the intestinal villus tip. Nat Commun. 2020;11:1936 pubmed publisher
Han Y, Jia Q, Jahani P, Hurrell B, Pan C, Huang P, et al. Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma. Nat Commun. 2020;11:1776 pubmed publisher
Pan J, Ma N, Yu B, Zhang W, Wan J. Transcriptomic profiling of microglia and astrocytes throughout aging. J Neuroinflammation. 2020;17:97 pubmed publisher
Muri J, Feng Q, Wolleb H, Shamshiev A, Ebner C, Tortola L, et al. Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways. Cell Rep. 2020;30:4399-4417.e7 pubmed publisher
Court A, Le Gatt A, Luz Crawford P, Parra E, Aliaga Tobar V, Batiz L, et al. Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response. EMBO Rep. 2020;21:e48052 pubmed publisher
Wu J, Li Y, Chen A, Hong C, Zhang C, Wang H, et al. Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy. EMBO Mol Med. 2020;12:e10154 pubmed publisher
Wu H, Yu Y, Huang H, Hu Y, Fu S, Wang Z, et al. Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells. Cell. 2020;180:107-121.e17 pubmed publisher
Chen C, Yu W, Tober J, Gao P, He B, Lee K, et al. Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells. Cell Rep. 2019;29:4200-4211.e7 pubmed publisher
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Dobie R, Wilson Kanamori J, Henderson B, Smith J, Matchett K, Portman J, et al. Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis. Cell Rep. 2019;29:1832-1847.e8 pubmed publisher
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Li S, Lu X, Shao Q, Chen Z, Huang Q, Jiao Z, et al. Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype. Front Neurol. 2019;10:893 pubmed publisher
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Dubey L, Ludewig B, Luther S, Harris N. IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells. Cell Rep. 2019;27:2442-2458.e5 pubmed publisher
Kellish P, Shabashvili D, Rahman M, Nawab A, Guijarro M, Zhang M, et al. Oncolytic virotherapy for small-cell lung cancer induces immune infiltration and prolongs survival. J Clin Invest. 2019;129:2279-2292 pubmed publisher
Wilson R, Tursi S, Rapsinski G, Medeiros N, Le L, Kotredes K, et al. STAT2 dependent Type I Interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium. PLoS Pathog. 2019;15:e1007745 pubmed publisher
Saleh M, Frisbee A, Leslie J, Buonomo E, Cowardin C, Ma J, et al. Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection. Cell Host Microbe. 2019;25:756-765.e5 pubmed publisher
Cheng H, Onder L, Novković M, Soneson C, Lütge M, Pikor N, et al. Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun. 2019;10:1739 pubmed publisher
Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed publisher
Codina A, Renauer P, Wang G, Chow R, Park J, Ye H, et al. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Syst. 2019;8:136-151.e7 pubmed publisher
Galle Treger L, Sankaranarayanan I, Hurrell B, Howard E, Lo R, Maazi H, et al. Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes. Nat Commun. 2019;10:713 pubmed publisher
Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, et al. Liver-Resident NK Cells Control Antiviral Activity of Hepatic T Cells via the PD-1-PD-L1 Axis. Immunity. 2019;50:403-417.e4 pubmed publisher
Yoshida H, Lareau C, Ramirez R, Rose S, Maier B, Wroblewska A, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019;176:897-912.e20 pubmed publisher
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Gubin M, Esaulova E, Ward J, Malkova O, Runci D, Wong P, et al. High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy. Cell. 2018;175:1014-1030.e19 pubmed publisher
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Smith N, Swain J, Davies P, Gallagher A, Parappilly M, Beach C, et al. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol. 2018;6:79-96 pubmed publisher
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McGowan S, McCoy D. Neuropilin-1 and platelet-derived growth factor receptors cooperatively regulate intermediate filaments and mesenchymal cell migration during alveolar septation. Am J Physiol Lung Cell Mol Physiol. 2018;315:L102-L115 pubmed publisher
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Galvão I, Tavares L, Correa R, Fachi J, Rocha V, Rungue M, et al. The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung. Front Immunol. 2018;9:142 pubmed publisher
Garber C, Vasek M, Vollmer L, Sun T, Jiang X, Klein R. Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via IL-1. Nat Immunol. 2018;19:151-161 pubmed publisher
Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed publisher
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Wang B, Fu X, Liang X, Deavila J, Wang Z, Zhao L, et al. Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRα+ adipose progenitors. Cell Discov. 2017;3:17036 pubmed publisher
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Magri G, Comerma L, Pybus M, Sintes J, Lligé D, Segura Garzón D, et al. Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals. Immunity. 2017;47:118-134.e8 pubmed publisher
Onder L, Mörbe U, Pikor N, Novković M, Cheng H, Hehlgans T, et al. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity. 2017;47:80-92.e4 pubmed publisher
Chang T, Huang J, Lin H, Chen W, Lee Y, Hsu L, et al. Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum. PLoS Pathog. 2017;13:e1006485 pubmed publisher
Nenasheva T, Nikolaev A, Diykanov D, Sukhanova A, Tcyganov E, Panteleev A, et al. The introduction of mesenchymal stromal cells induces different immunological responses in the lungs of healthy and M. tuberculosis infected mice. PLoS ONE. 2017;12:e0178983 pubmed publisher
Smith N, Davies P, Levin T, Gallagher A, Keene D, Sengupta S, et al. Cell Adhesion Molecule CD166/ALCAM Functions Within the Crypt to Orchestrate Murine Intestinal Stem Cell Homeostasis. Cell Mol Gastroenterol Hepatol. 2017;3:389-409 pubmed publisher
Wang B, Fu X, Liang X, Wang Z, Yang Q, Zou T, et al. Maternal Retinoids Increase PDGFR?+ Progenitor Population and Beige Adipogenesis in Progeny by Stimulating Vascular Development. EBioMedicine. 2017;18:288-299 pubmed publisher
Bussières Marmen S, Vinette V, Gungabeesoon J, Aubry I, Pérez Quintero L, Tremblay M. Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation. Cell Mol Immunol. 2018;15:367-376 pubmed publisher
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product information
Antigen :
CD45
Apps. Abbrev. :
FC
Cat # :
103114
Clone :
30-F11
Item :
PE/Cyanine7 anti-mouse CD45
Isotype :
Rat IgG2b, κ
Other Names :
T200, Ly-5, LCA
Size :
100 μg
Price (USD) :
190 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
Mouse thymus or spleen
Application Notes :
Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.Additional reported applications (for relevant formats) include: immunoprecipitation^3, complement-dependent cytotoxicity^1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)^4,6, Western blotting^7, and spatial biology (IBEX)^10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA