Brilliant Violet 421™ anti-mouse/human CD44 | BioLegend 103039 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-mouse/human CD44

catalog :

103039

quantity :

125 μL

price :

176 USD

clonality :

monoclonal

host :

rat

conjugate :

BV421

clone name :

IM7

reactivity :

human, mouse

application :

immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 31

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 5a	Findlay E, Currie A, Zhang A, Ovciarikova J, Young L, Stevens H, et al. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. Oncoimmunology. 2019;8:1608106 pubmed publisher
flow cytometry; mouse; loading ...; fig 5c	Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. 2019;176:998-1013.e16 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Vuckovic S, Minnie S, Smith D, Gartlan K, Watkins T, Markey K, et al. Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019;129:106-121 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 2b	Morita K, Okamura T, Inoue M, Komai T, Teruya S, Iwasaki Y, et al. Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-Î²3 production. Proc Natl Acad Sci U S A. 2016;113:E8131-E8140 pubmed
	Zhu G, Du S, Wang Y, Huang X, Hu G, Lu X, et al. Delayed Antiviral Immune Responses in Severe Acute Respiratory Syndrome Coronavirus Infected Pregnant Mice. Front Microbiol. 2021;12:806902 pubmed publisher
	Marangoni F, Zhakyp A, Corsini M, Geels S, Carrizosa E, Thelen M, et al. Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell. 2021;184:3998-4015.e19 pubmed publisher
	Kawakami R, Kitagawa Y, Chen K, Arai M, Ohara D, Nakamura Y, et al. Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells. Immunity. 2021;54:947-961.e8 pubmed publisher
	Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed publisher
	Ciesla M, Ngoc P, Cordero E, Martinez Á, Morsing M, Muthukumar S, et al. Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer. Mol Cell. 2021;81:1453-1468.e12 pubmed publisher
	Wirasinha R, Davies A, Srivastava M, Sheridan J, Sng X, Delmonte O, et al. Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility. J Exp Med. 2021;218: pubmed publisher
	Wu J, Madi A, Mieg A, Hotz Wagenblatt A, Weisshaar N, Ma S, et al. T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development. Cell Rep. 2020;31:107484 pubmed publisher
	Frohner I, Mudrak I, Schüchner S, Anrather D, Hartl M, Sontag J, et al. PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation. Cell Rep. 2020;30:3171-3182.e6 pubmed publisher
	Andersen L, Gülich A, Alteneder M, Preglej T, Orola M, Dhele N, et al. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. Cell Rep. 2019;29:4447-4459.e6 pubmed publisher
	Chow M, Ozga A, Servis R, Frederick D, Lo J, Fisher D, et al. Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy. Immunity. 2019;: pubmed publisher
	Sonzogni O, Haynes J, Seifried L, Kamel Y, Huang K, BeGora M, et al. Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol. 2018;16:e2004049 pubmed publisher
	Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
	Slamecka J, McClellan S, Wilk A, Laurini J, Manci E, Hoerstrup S, et al. Induced pluripotent stem cells derived from human amnion in chemically defined conditions. Cell Cycle. 2018;17:330-347 pubmed publisher
	Wiese A, Ender F, Quell K, Antoniou K, Vollbrandt T, Konig P, et al. The C5a/C5aR1 axis controls the development of experimental allergic asthma independent of LysM-expressing pulmonary immune cells. PLoS ONE. 2017;12:e0184956 pubmed publisher
	Moguche A, Musvosvi M, Penn Nicholson A, Plumlee C, Mearns H, Geldenhuys H, et al. Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis. Cell Host Microbe. 2017;21:695-706.e5 pubmed publisher
	McClellan S, Slamecka J, Howze P, Thompson L, Finan M, Rocconi R, et al. mRNA detection in living cells: A next generation cancer stem cell identification technique. Methods. 2015;82:47-54 pubmed publisher
	Yang Y, Gomez J, Herrera M, Perez Marco R, Repenning P, Zhang Z, et al. Salt restriction leads to activation of adult renal mesenchymal stromal cell-like cells via prostaglandin E2 and E-prostanoid receptor 4. Hypertension. 2015;65:1047-54 pubmed publisher
	Hirokawa Y, Yip K, Tan C, Burgess A. Colonic myofibroblast cell line stimulates colonoid formation. Am J Physiol Gastrointest Liver Physiol. 2014;306:G547-56 pubmed publisher
	Chen Y, Chen K, Huang P, Chen Y, Chiou G, Lo W, et al. Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma--derived CD44(+)ALDH1(+) cells. Mol Cancer Ther. 2010;9:2879-92 pubmed publisher
	Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher
	Yamazaki J, Mizukami T, Takizawa K, Kuramitsu M, Momose H, Masumi A, et al. Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma. Blood. 2009;114:2709-20 pubmed publisher
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product information

Antigen :

CD44

Apps. Abbrev. :

FC, ICC, IHC-P

Cat # :

103039

Clone :

IM7

Item :

Brilliant Violet 421™ anti-mouse/human CD44

Isotype :

Rat IgG2b, κ

Other Names :

Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24

Size :

125 μL

Price (USD) :

176 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV421

Immunogen :

Dexamethasone-induced myeloid leukemia M1 cells

Application Notes :

Clone IM7 has been reported to recognize an epitope common to alloantigens and all isoforms of CD44^17,18 that is located between amino acids 145 and 186^20. This clone has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections^6,7, complement-mediated cytotoxicity^1, immunoprecipitation^1,3, in vivo inhibition of DTH^4,5, and spatial biology (IBEX)^23,24. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103046, 103065 - 103069).Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.;

more info or order :

BioLegend product webpage