Biotin anti-mouse/human CD44 | BioLegend 103003 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Biotin anti-mouse/human CD44

catalog :

103003

quantity :

50 μg

price :

42 USD

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

IM7

reactivity :

human, mouse

application :

immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 31

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig 4e	Bradford B, McGuire L, Hume D, Pridans C, Mabbott N. Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain. Glia. 2022;70:2169-2187 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 6a	Donaldson D, Bradford B, Else K, Mabbott N. Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase. Sci Rep. 2020;10:4554 pubmed publisher
	Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, et al. Mitochondrial C1qbp promotes differentiation of effector CD8+ T cells via metabolic-epigenetic reprogramming. Sci Adv. 2021;7:eabk0490 pubmed publisher
	Priglinger E, Strasser J, Buchroithner B, Weber F, Wolbank S, Auer D, et al. Label-free characterization of an extracellular vesicle-based therapeutic. J Extracell Vesicles. 2021;10:e12156 pubmed publisher
	Izumi G, Nakano H, Nakano K, Whitehead G, Grimm S, Fessler M, et al. CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation. Nat Commun. 2021;12:5029 pubmed publisher
	Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, et al. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2. J Cell Biol. 2020;219: pubmed publisher
	Frohner I, Mudrak I, Schüchner S, Anrather D, Hartl M, Sontag J, et al. PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation. Cell Rep. 2020;30:3171-3182.e6 pubmed publisher
	Horková V, Drobek A, Mueller D, Gubser C, Niederlova V, Wyss L, et al. Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells. Cell Rep. 2020;30:1504-1514.e7 pubmed publisher
	Martínez López M, Iborra S, Conde Garrosa R, Mastrangelo A, Danne C, Mann E, et al. Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity. Immunity. 2019;50:446-461.e9 pubmed publisher
	Shimada K, Porritt R, Markman J, O Rourke J, Wakita D, Noval Rivas M, et al. T-Cell-Intrinsic Receptor Interacting Protein 2 Regulates Pathogenic T Helper 17 Cell Differentiation. Immunity. 2018;49:873-885.e7 pubmed publisher
	Boulais P, Mizoguchi T, Zimmerman S, Nakahara F, Vivié J, Mar J, et al. The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors. Immunity. 2018;49:627-639.e6 pubmed publisher
	Lin H, Zhou J, Cao L, Wang H, Dong J, Chen Z. Tissue-engineered cartilage constructed by a biotin-conjugated anti-CD44 avidin binding technique for the repairing of cartilage defects in the weight-bearing area of knee joints in pigs. Bone Joint Res. 2017;6:284-295 pubmed publisher
	Akkaya B, Holstein A, Isaac C, Maz M, Glass D, Shevach E, et al. Ex-vivo iTreg differentiation revisited: Convenient alternatives to existing strategies. J Immunol Methods. 2017;441:67-71 pubmed publisher
	Ma C, Mishra S, Demel E, Liu Y, Zhang N. TGF-? Controls the Formation of Kidney-Resident T Cells via Promoting Effector T Cell Extravasation. J Immunol. 2017;198:749-756 pubmed publisher
	Blanco S, Bandiera R, Popis M, Hussain S, Lombard P, Aleksic J, et al. Stem cell function and stress response are controlled by protein synthesis. Nature. 2016;534:335-40 pubmed publisher
	Tian Y, Cox M, Kahan S, Ingram J, Bakshi R, Zajac A. A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets. J Immunol. 2016;196:2153-66 pubmed publisher
	Wolf I, Diercks B, Gattkowski E, Czarniak F, Kempski J, Werner R, et al. Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor. Sci Signal. 2015;8:ra102 pubmed publisher
	Yang Y, Gomez J, Herrera M, Perez Marco R, Repenning P, Zhang Z, et al. Salt restriction leads to activation of adult renal mesenchymal stromal cell-like cells via prostaglandin E2 and E-prostanoid receptor 4. Hypertension. 2015;65:1047-54 pubmed publisher
	Hirokawa Y, Yip K, Tan C, Burgess A. Colonic myofibroblast cell line stimulates colonoid formation. Am J Physiol Gastrointest Liver Physiol. 2014;306:G547-56 pubmed publisher
	Chen Y, Chen K, Huang P, Chen Y, Chiou G, Lo W, et al. Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma--derived CD44(+)ALDH1(+) cells. Mol Cancer Ther. 2010;9:2879-92 pubmed publisher
	Takeuchi H, Yokota A, Ohoka Y, Kagechika H, Kato C, Song S, et al. Efficient induction of CCR9 on T cells requires coactivation of retinoic acid receptors and retinoid X receptors (RXRs): exaggerated T Cell homing to the intestine by RXR activation with organotins. J Immunol. 2010;185:5289-99 pubmed publisher
	Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher
	Yamazaki J, Mizukami T, Takizawa K, Kuramitsu M, Momose H, Masumi A, et al. Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma. Blood. 2009;114:2709-20 pubmed publisher
	Wang X, Lan Y, He W, Zhang L, Yao H, Hou C, et al. Identification of mesenchymal stem cells in aorta-gonad-mesonephros and yolk sac of human embryos. Blood. 2008;111:2436-43 pubmed
	Kenna T, Thomas R, Steptoe R. Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses. Blood. 2008;111:2091-100 pubmed
	Gui J, Zhu X, Dohkan J, Cheng L, Barnes P, Su D. The aged thymus shows normal recruitment of lymphohematopoietic progenitors but has defects in thymic epithelial cells. Int Immunol. 2007;19:1201-11 pubmed
	Small M. Jagged-1hi or Delta-1hi thymic stromal cell populations can trigger acquisition of Thy-1 and loss of B220. Dev Comp Immunol. 2006;30:966-73 pubmed
	Fukushima A, Yamaguchi T, Ishida W, Fukata K, Yagita H, Ueno H. Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation by stimulation and blocking of OX40. Invest Ophthalmol Vis Sci. 2006;47:657-63 pubmed
	Chen H, Hou J, Jiang X, Ma S, Meng M, Wang B, et al. Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals. J Immunol. 2005;175:591-8 pubmed
	Zhang N, He Y. The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes. J Immunol. 2005;174:6967-73 pubmed
	Frank N, Margaryan A, Huang Y, Schatton T, Waaga Gasser A, Gasser M, et al. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res. 2005;65:4320-33 pubmed

product information

Antigen :

CD44

Apps. Abbrev. :

FC, ICC, IHC-P

Cat # :

103003

Clone :

IM7

Item :

Biotin anti-mouse/human CD44

Isotype :

Rat IgG2b, κ

Other Names :

Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24

Size :

50 μg

Price (USD) :

42 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BIOTIN

Immunogen :

Dexamethasone-induced myeloid leukemia M1 cells

Application Notes :

Clone IM7 has been reported to recognize an epitope common to alloantigens and all isoforms of CD44^17,18 that is located between amino acids 145 and 186^20. This clone has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections^6,7, complement-mediated cytotoxicity^1, immunoprecipitation^1,3, in vivo inhibition of DTH^4,5, and spatial biology (IBEX)^23,24. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103046, 103065 - 103069).Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.;

more info or order :

BioLegend product webpage