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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD40
catalog :
102902
quantity :
500 μg
price :
229 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
HM40-3
reactivity :
mouse
application :
neutralization, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments, mass cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed publisher
  • mass cytometry; mouse; loading ...; fig 5s2b
Dosch M, Zindel J, Jebbawi F, Melin N, Sánchez Taltavull D, Stroka D, et al. Connexin-43-dependent ATP release mediates macrophage activation during sepsis. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Yao Y, Huang W, Li X, Li X, Qian J, Han H, et al. Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice. Front Immunol. 2018;9:965 pubmed publisher
  • blocking or activating experiments; mouse; 10 ug/ml
Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed
Kobayashi A, Ito A, Shirakawa I, Tamura A, Tomono S, Shindou H, et al. Dietary Supplementation With Eicosapentaenoic Acid Inhibits Plasma Cell Differentiation and Attenuates Lupus Autoimmunity. Front Immunol. 2021;12:650856 pubmed publisher
Lindner S, Egelston C, Huard S, Lee P, Wang L. Arhgap25 Deficiency Leads to Decreased Numbers of Peripheral Blood B Cells and Defective Germinal Center Reactions. Immunohorizons. 2020;4:274-281 pubmed publisher
Berry C, Liu X, Myles A, Nandi S, Chen Y, Hershberg U, et al. BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells. Cell Rep. 2020;31:107474 pubmed publisher
Michaud D, Mirlekar B, Bischoff S, Cowley D, Vignali D, Pylayeva Gupta Y. Pancreatic cancer-associated inflammation drives dynamic regulation of p35 and Ebi3. Cytokine. 2020;125:154817 pubmed publisher
Sundaravinayagam D, Rahjouei A, Andreani M, Tupiņa D, Balasubramanian S, Saha T, et al. 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function. Cell Rep. 2019;28:1389-1399.e6 pubmed publisher
Mitsumura T, Ito Y, Chiba T, Matsushima T, Kurimoto R, Tanaka Y, et al. Ablation of miR-146b in mice causes hematopoietic malignancy. Blood Adv. 2018;2:3483-3491 pubmed publisher
Sin S, Eason A, Bigi R, Kim Y, Kang S, Tan K, et al. Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections. J Virol. 2018;92: pubmed publisher
Jimenez R, Wright T, Jones N, Wu J, Gibson A, Szalai A. C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance. Front Immunol. 2018;9:372 pubmed publisher
Sáez de Guinoa J, Jimeno R, Gaya M, Kipling D, Garzón M, Dunn Walters D, et al. CD1d-mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis. EMBO J. 2018;37: pubmed publisher
Schüler F, Weiss J, Lindner S, Lohmüller M, Herzog S, Spiegl S, et al. Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis. Nat Commun. 2017;8:1697 pubmed publisher
Garg G, Nikolouli E, Hardtke Wolenski M, Toker A, Ohkura N, Beckstette M, et al. Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells. Oncotarget. 2017;8:35542-35557 pubmed publisher
Folgosa L, Zellner H, El Shikh M, Conrad D. Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-? shedding. J Immunol. 2013;191:5951-8 pubmed publisher
del Rio M, Cote Sierra J, Rodriguez Barbosa J. Flt3L-mobilized dendritic cells bearing H2-Kbm1 apoptotic cells do not induce cross-tolerance to CD8+ T cells across a class I MHC mismatched barrier. Transpl Int. 2011;24:501-13 pubmed publisher
Ait Oufella H, Herbin O, Bouaziz J, Binder C, Uyttenhove C, Laurans L, et al. B cell depletion reduces the development of atherosclerosis in mice. J Exp Med. 2010;207:1579-87 pubmed publisher
Yu X, Siegel R, Roeder R. Interaction of the B cell-specific transcriptional coactivator OCA-B and galectin-1 and a possible role in regulating BCR-mediated B cell proliferation. J Biol Chem. 2006;281:15505-16 pubmed
product information
Antigen :
CD40
Apps. Abbrev. :
FC, Block, Costim, IHC-F
Cat # :
102902
Clone :
HM40-3
Item :
Purified anti-mouse CD40
Isotype :
Armenian Hamster IgM
Other Names :
Bp50, TNFRSF5
Size :
500 μg
Price (USD) :
229 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PURE
Immunogen :
(BALB/c x NZB)F 1 mouse-derived lymphoma WEHI 231
Application Notes :
Additional reported applications (for the relevant formats) include: blocking of CD40 ligand binding^1, stimulation of mouse B cell and dendritic cell proliferation^2-6,9, and immunohistochemistry^7 of acetone-fixed frozen sections. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 102908).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA