product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD31
catalog :
102401
quantity :
50 μg
price :
54 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
390
reactivity :
mouse
application :
immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 71
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig s1b
Yue X, Yin J, Wang X, Heidecke H, Hackel A, Dong X, et al. Induced antibodies directed to the angiotensin receptor type 1 provoke skin and lung inflammation, dermal fibrosis and act species overarching. Ann Rheum Dis. 2022;81:1281-9 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1h
Lin J, Chen Y, Zhu H, Cheng K, Wang H, Yu X, et al. Lymphatic Reconstruction in Kidney Allograft Aggravates Chronic Rejection by Promoting Alloantigen Presentation. Front Immunol. 2021;12:796260 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Hayakawa M, Sakata A, Hayakawa H, Matsumoto H, Hiramoto T, Kashiwakura Y, et al. Characterization and visualization of murine coagulation factor VIII-producing cells in vivo. Sci Rep. 2021;11:14824 pubmed publisher
  • flow cytometry; mouse; 1:200; fig 1d
Uezumi A, Ikemoto Uezumi M, Zhou H, Kurosawa T, Yoshimoto Y, Nakatani M, et al. Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia. J Clin Invest. 2021;131: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5b
Taniguchi Y, Oyama N, Fumoto S, Kinoshita H, Yamashita F, Shimizu K, et al. Tissue suction-mediated gene transfer to the beating heart in mice. PLoS ONE. 2020;15:e0228203 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6s2
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6a
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig ev3a
Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, et al. Length-independent telomere damage drives post-mitotic cardiomyocyte senescence. EMBO J. 2019;38: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3a
Rowe R, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W, et al. The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia. J Exp Med. 2019;216:527-538 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2b
Cornelissen L, Blanas A, van der Horst J, Kruijssen L, Zaal A, O Toole T, et al. Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis. Int J Cancer. 2019;144:2290-2302 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2
Jürgensen H, Nørregaard K, Sibree M, Santoni Rugiu E, Madsen D, Wassilew K, et al. Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins. J Cell Biol. 2019;218:333-349 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; fig 4a
Oldstone M, Ware B, Horton L, Welch M, Aiolfi R, Zarpellon A, et al. Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics. Proc Natl Acad Sci U S A. 2018;115:E7814-E7823 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
  • flow cytometry; mouse; loading ...
Ramos G, van den Berg A, Nunes Silva V, Weirather J, Peters L, Burkard M, et al. Myocardial aging as a T-cell-mediated phenomenon. Proc Natl Acad Sci U S A. 2017;114:E2420-E2429 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3d
Turner V, Mabbott N. Structural and functional changes to lymph nodes in ageing mice. Immunology. 2017;151:239-247 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6b
Weeden C, Chen Y, Ma S, Hu Y, Ramm G, Sutherland K, et al. Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway. PLoS Biol. 2017;15:e2000731 pubmed publisher
  • flow cytometry; mouse; 1:100; fig 7e
Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, et al. Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest. 2017;127:383-401 pubmed publisher
  • flow cytometry; mouse; fig 6a
Swanson P, Hart G, Russo M, Nayak D, Yazew T, Pena M, et al. CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature. PLoS Pathog. 2016;12:e1006022 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Lu X, Chen Q, Rong Y, Yang G, Li C, Xu N, et al. LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells. Nat Commun. 2016;7:12719 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
  • flow cytometry; mouse; fig s8
Li Y, Nishikawa T, Kaneda Y. Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation. Sci Rep. 2016;6:25077 pubmed publisher
  • flow cytometry; mouse; fig 2
Gawade S, Mayer C, Hafen K, Barthlott T, Krenger W, Szinnai G. Cell Growth Dynamics in Embryonic and Adult Mouse Thyroid Revealed by a Novel Approach to Detect Thyroid Gland Subpopulations. Thyroid. 2016;26:591-9 pubmed publisher
  • flow cytometry; mouse; fig 8
Lindemans C, Calafiore M, Mertelsmann A, O Connor M, Dudakov J, Jenq R, et al. Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration. Nature. 2015;528:560-564 pubmed publisher
  • flow cytometry; mouse; fig 1a
Tsukui T, Ueha S, Shichino S, Inagaki Y, Matsushima K. Intratracheal cell transfer demonstrates the profibrotic potential of resident fibroblasts in pulmonary fibrosis. Am J Pathol. 2015;185:2939-48 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 1c
  • flow cytometry; mouse; fig 1d
Sun L, Sun C, Liang Z, Li H, Chen L, Luo H, et al. FSP1(+) fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells. Sci Rep. 2015;5:14871 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5d
Santoro S, Kim S, Motz G, Alatzoglou D, Li C, Irving M, et al. T cells bearing a chimeric antigen receptor against prostate-specific membrane antigen mediate vascular disruption and result in tumor regression. Cancer Immunol Res. 2015;3:68-84 pubmed publisher
  • flow cytometry; mouse; fig 2
Cremasco V, Woodruff M, Onder L, Cupovic J, Nieves Bonilla J, Schildberg F, et al. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol. 2014;15:973-81 pubmed publisher
  • flow cytometry; mouse
Caswell D, Chuang C, Yang D, Chiou S, Cheemalavagu S, Kim Kiselak C, et al. Obligate progression precedes lung adenocarcinoma dissemination. Cancer Discov. 2014;4:781-9 pubmed publisher
Sugita Y, Takada S, Tanigaki K, Muraki K, Uemura M, Hojo M, et al. Inhibition of VEGF receptors induces pituitary apoplexy: An experimental study in mice. PLoS ONE. 2023;18:e0279634 pubmed publisher
Wei G, Zhang S, Yu S, Lu W. Intravital Microscopy Reveals Endothelial Transcytosis Contributing to Significant Tumor Accumulation of Albumin Nanoparticles. Pharmaceutics. 2023;15: pubmed publisher
Shin J, An S, Kim D, Kim H, Ahn J, Eom J, et al. Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier. Cell Rep Methods. 2022;2:100338 pubmed publisher
Rodionov R, Jarzebska N, Burdin D, Todorov V, Martens Lobenhoffer J, Hofmann A, et al. Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling. Sci Rep. 2022;12:9381 pubmed publisher
Murray C, Brady J, Han M, Cai H, Tsai M, Pierce S, et al. LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer. Nat Commun. 2022;13:1090 pubmed publisher
Daskou M, Mu W, Sharma M, Vasilopoulos H, Heymans R, Ritou E, et al. ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV. PLoS Pathog. 2022;18:e1010160 pubmed publisher
Stefanescu C, van Gogh M, Roblek M, Heikenwalder M, Borsig L. TGFβ Signaling in Myeloid Cells Promotes Lung and Liver Metastasis Through Different Mechanisms. Front Oncol. 2021;11:765151 pubmed publisher
Kimishima Y, Misaka T, Yokokawa T, Wada K, Ueda K, Sugimoto K, et al. Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils. Nat Commun. 2021;12:6177 pubmed publisher
Yan S, Kehrl J. An optimized confocal intravital microscopy protocol for long-term live imaging of murine F-actin organization during naïve lymphocyte migration. STAR Protoc. 2021;2:100498 pubmed publisher
Gonz xe1 lez L, Melo Gonz xe1 lez F, Sebasti xe1 n V, Vallejos O, Noguera L, Suazo I, et al. Characterization of the Anti-Inflammatory Capacity of IL-10-Producing Neutrophils in Response to Streptococcus pneumoniae Infection. Front Immunol. 2021;12:638917 pubmed publisher
Nguyen S, Ahn S, Greenberg J, Collaer B, Agnew D, Arora R, et al. Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo. Sci Rep. 2021;11:4217 pubmed publisher
Khera E, Cilliers C, Smith M, Ganno M, Lai K, Keating T, et al. Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping. Neoplasia. 2021;23:210-221 pubmed publisher
Khoa L, Dou Y. In Vitro Derivation of Quiescent Mouse Embryonic Stem Cells Based on Distinct Mitochondrial Activity. STAR Protoc. 2020;1:100136 pubmed publisher
Sun W, Khare P, Wang X, Challa D, Greenberg B, Ober R, et al. Selective Depletion of Antigen-Specific Antibodies for the Treatment of Demyelinating Disease. Mol Ther. 2021;29:1312-1323 pubmed publisher
Chamberlin T, Clack M, Silvers C, Kuziel G, Thompson V, Johnson H, et al. Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation. Cancer Res. 2020;80:4465-4475 pubmed publisher
Subramanian B, Melis N, Chen D, Wang W, Gallardo D, Weigert R, et al. The LTB4-BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation. J Cell Biol. 2020;219: pubmed publisher
Alexandrushkina N, Nimiritsky P, Eremichev R, Popov V, Arbatskiy M, Danilova N, et al. Cell Sheets from Adipose Tissue MSC Induce Healing of Pressure Ulcer and Prevent Fibrosis via Trigger Effects on Granulation Tissue Growth and Vascularization. Int J Mol Sci. 2020;21: pubmed publisher
Gong F, Cheng L, Yang N, Gong Y, Ni Y, Bai S, et al. Preparation of TiH1.924 nanodots by liquid-phase exfoliation for enhanced sonodynamic cancer therapy. Nat Commun. 2020;11:3712 pubmed publisher
Xiong S, Hong Z, Huang L, Tsukasaki Y, Nepal S, Di A, et al. IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury. J Clin Invest. 2020;130:3684-3698 pubmed publisher
Bertrand J, Schicht M, Stamer W, Baker D, Sherwood J, Lütjen Drecoll E, et al. The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice. Invest Ophthalmol Vis Sci. 2020;61:41 pubmed publisher
Donati Y, Blasković S, Ruchonnet M xe9 trailler I, Lascano Maillard J, Barazzone Argiroffo C. Simultaneous isolation of endothelial and alveolar epithelial type I and type II cells during mouse lung development in the absence of a transgenic reporter. Am J Physiol Lung Cell Mol Physiol. 2020;318:L619-L630 pubmed publisher
Blasković S, Donati Y, Zanetti F, Ruchonnet M xe9 trailler I, Lemeille S, Cremona T, et al. Gestation and lactation exposure to nicotine induces transient postnatal changes in lung alveolar development. Am J Physiol Lung Cell Mol Physiol. 2020;318:L606-L618 pubmed publisher
Nessler I, Khera E, Vance S, Kopp A, Qiu Q, Keating T, et al. Increased Tumor Penetration of Single-Domain Antibody-Drug Conjugates Improves In Vivo Efficacy in Prostate Cancer Models. Cancer Res. 2020;80:1268-1278 pubmed publisher
Lim P, Duarte T, Arezes J, Garcia Santos D, Hamdi A, Pasricha S, et al. Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin. Nat Metab. 2019;1:519-531 pubmed publisher
Tamburini B, Finlon J, Gillen A, Kriss M, Riemondy K, Fu R, et al. Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells. Front Immunol. 2019;10:1036 pubmed publisher
Vu L, Peng B, Zhang D, Ma V, Mathey Andrews C, Lam C, et al. Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b. J Extracell Vesicles. 2019;8:1599680 pubmed publisher
Dubrot J, Durães F, Harlé G, Schlaeppi A, Brighouse D, Madelon N, et al. Absence of MHC-II expression by lymph node stromal cells results in autoimmunity. Life Sci Alliance. 2018;1:e201800164 pubmed publisher
Paulo E, Wu D, Wang Y, Zhang Y, Wu Y, Swaney D, et al. Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis. Sci Rep. 2018;8:11001 pubmed publisher
Bhatnagar S, Verma K, Hu Y, Khera E, Priluck A, Smith D, et al. Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening. Mol Pharm. 2018;15:1746-1754 pubmed publisher
Shin J, Fukuhara A, Onodera T, Kita S, Yokoyama C, Otsuki M, et al. SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes. Diabetes. 2018;67:1068-1078 pubmed publisher
Eslani M, Putra I, Shen X, Hamouie J, Tadepalli A, Anwar K, et al. Cornea-Derived Mesenchymal Stromal Cells Therapeutically Modulate Macrophage Immunophenotype and Angiogenic Function. Stem Cells. 2018;36:775-784 pubmed publisher
Wang W, Xu B, Xuan H, Ge Y, Wang Y, Wang L, et al. Hypoxia-inducible factor 1 in clinical and experimental aortic aneurysm disease. J Vasc Surg. 2018;68:1538-1550.e2 pubmed publisher
Cilliers C, Menezes B, Nessler I, Linderman J, Thurber G. Improved Tumor Penetration and Single-Cell Targeting of Antibody-Drug Conjugates Increases Anticancer Efficacy and Host Survival. Cancer Res. 2018;78:758-768 pubmed publisher
Eslani M, Putra I, Shen X, Hamouie J, Afsharkhamseh N, Besharat S, et al. Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1. Invest Ophthalmol Vis Sci. 2017;58:5507-5517 pubmed publisher
Molica F, Meens M, Dubrot J, Ehrlich A, Roth C, Morel S, et al. Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis. Sci Rep. 2017;7:13706 pubmed publisher
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Stepanova V, Jayaraman P, Zaitsev S, Lebedeva T, Bdeir K, Kershaw R, et al. Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression. J Biol Chem. 2016;291:15029-45 pubmed publisher
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product information
Antigen :
CD31
Apps. Abbrev. :
FC, IHC-F, IP
Cat # :
102401
Clone :
390
Item :
Purified anti-mouse CD31
Isotype :
Rat IgG2a, κ
Other Names :
PECAM-1, EndoCAM
Size :
50 μg
Price (USD) :
54 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
C3H/HeJ mouse hematopoietic progenitor cell line 3
Application Notes :
Anti-mouse CD31 clones 390 and MEC13.3 bind to their respective non-overlapping epitopes in IgD2 of CD31.^8 Additional reported applications (for the relevant formats) include: immunoprecipitation^1, in vitro and in vivo blocking of CD31-mediated cell-cell interactions^1-4, and immunohistochemical staining^5,6,7 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections. Special Note: This antibody is not recommended for formalin-fixed paraffin-embedded sections. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 102412).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA