Pacific Blue™ anti-mouse CD25 | BioLegend 102022 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-mouse CD25

catalog :

102022

quantity :

100 μg

price :

215 USD

clonality :

monoclonal

host :

rat

conjugate :

Pacific Blue

clone name :

PC61

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Reference
Asadi Shahmirzadi A, Edgar D, Liao C, Hsu Y, Lucanic M, Asadi Shahmirzadi A, et al. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020;32:447-456.e6 pubmed publisher
Gomzikova M, Kletukhina S, Kurbangaleeva S, Neustroeva O, Vasileva O, Garanina E, et al. Mesenchymal Stem Cell Derived Biocompatible Membrane Vesicles Demonstrate Immunomodulatory Activity Inhibiting Activation and proliferation of Human Mononuclear Cells. Pharmaceutics. 2020;12: pubmed publisher
Kurniawan H, Franchina D, Guerra L, Bonetti L, Baguet L, Grusdat M, et al. Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metab. 2020;31:920-936.e7 pubmed publisher
Wang Y, Dong W, Zhang Y, Caligiuri M, Yu J. Dependence of innate lymphoid cell 1 development on NKp46. PLoS Biol. 2018;16:e2004867 pubmed publisher
Nakornpakdee Y, Sermswan R, Maneewatchararangsri S, Wongratanacheewin S. Hamster IFN-γ+CD4+ and IL-4+CD4+ T cell responses against leptospires are significantly higher than those of mice. Asian Pac J Allergy Immunol. 2018;36:265-272 pubmed publisher
Singh K, Hjort M, Thorvaldson L, Sandler S. Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naÃ¯ve mice. Sci Rep. 2015;5:7767 pubmed publisher
Joly M, Martin R, Mitra Kaushik S, Phillips L, D Angona A, Richards S, et al. Transient low-dose methotrexate generates B regulatory cells that mediate antigen-specific tolerance to alglucosidase alfa. J Immunol. 2014;193:3947-58 pubmed publisher
Ratsimandresy R, Duvallet E, Assier E, Semerano L, Delavallée L, Bessis N, et al. Active immunization against IL-23p19 improves experimental arthritis. Vaccine. 2011;29:9329-36 pubmed publisher

product information

Antigen :

CD25

Apps. Abbrev. :

Flow Cytometry

Cat # :

102022

Clone :

PC61

Item :

Pacific Blue™ anti-mouse CD25

Isotype :

Rat IgG1, λ

Other Names :

IL-2Rα, Ly-43, p55, Tac

Size :

100 μg

Price (USD) :

215 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

IL-2-dependent cytolytic mouse T-cell clone B6.1

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation 1,2 , in vitro blocking of IL-2 binding to low- and high-affinity receptors 1-4 , growth inhibition of IL-2-dependent T-cell lines 1-4 , in vivo depletion of CD25 + CD4 + Treg cells 5-8,10 , and immunohistochemical staining of acetone-fixed frozen sections 2 . PC61 antibody recognizes a different epitope than 3C7 antibody (Cat. No. 101902). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 102040) with endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered.

more info or order :

BioLegend product webpage