product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD23
catalog :
101602
quantity :
500 μg
price :
242 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
B3B4
reactivity :
mouse
application :
neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 32
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig s12b
Grootjans J, Krupka N, Hosomi S, Matute J, Hanley T, Saveljeva S, et al. Epithelial endoplasmic reticulum stress orchestrates a protective IgA response. Science. 2019;363:993-998 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Peng Y. B cell responses to apoptotic cells in MFG-E8-/- mice. PLoS ONE. 2018;13:e0205172 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s4a
Sang A, Danhorn T, Peterson J, Rankin A, O Connor B, Leach S, et al. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun. 2018;9:3973 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4g
Lin Y, Pecetta S, Steichen J, Kratochvil S, Melzi E, Arnold J, et al. One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice. EMBO J. 2018;37: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Bröker K, Figge J, Magnusen A, Manz R, Köhl J, Karsten C. A Novel Role for C5a in B-1 Cell Homeostasis. Front Immunol. 2018;9:258 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4e
Tang C, Chang S, Paton A, Paton J, Gabrilovich D, Ploegh H, et al. Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. J Cell Biol. 2018;217:1739-1755 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4j
Clarke A, Riffelmacher T, Braas D, Cornall R, Simon A. B1a B cells require autophagy for metabolic homeostasis and self-renewal. J Exp Med. 2018;215:399-413 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Yu J, Zanotti S, Walia B, JELLISON E, Sanjay A, Canalis E. The Hajdu Cheney Mutation Is a Determinant of B-Cell Allocation of the Splenic Marginal Zone. Am J Pathol. 2018;188:149-159 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Turner V, Mabbott N. Ageing adversely affects the migration and function of marginal zone B cells. Immunology. 2017;151:349-362 pubmed publisher
  • flow cytometry; mouse; loading ...
Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Gallagher S, Turman S, Lekstrom K, Wilson S, Herbst R, Wang Y. CD47 limits antibody dependent phagocytosis against non-malignant B cells. Mol Immunol. 2017;85:57-65 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s6b
Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Xue D, Desjardins M, Kaufman G, Beland M, Al Tamemi S, Ahmed E, et al. Semaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses. Front Immunol. 2016;7:558 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Carroll V, Lafferty M, Marchionni L, Bryant J, Gallo R, Garzino Demo A. Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice. Proc Natl Acad Sci U S A. 2016;113:13168-13173 pubmed
  • flow cytometry; mouse; fig 4a
Milanovic M, Heise N, De Silva N, Anderson M, Silva K, Carette A, et al. Differential requirements for the canonical NF-?B transcription factors c-REL and RELA during the generation and activation of mature B cells. Immunol Cell Biol. 2017;95:261-271 pubmed publisher
  • flow cytometry; mouse; fig s1
Kong S, Yang Y, Xu Y, Wang Y, Zhang Y, Melo Cardenas J, et al. Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas. Proc Natl Acad Sci U S A. 2016;113:10394-9 pubmed publisher
  • flow cytometry; mouse; fig s5
Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed publisher
  • flow cytometry; mouse; loading ...; fig cd23
Leeth C, Racine J, Chapman H, Arpa B, Carrillo J, Carrascal J, et al. B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice. Diabetes. 2016;65:1977-1987 pubmed publisher
  • flow cytometry; mouse; fig s1
Levit Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity P, Rajewsky K, et al. Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function. J Immunol. 2016;196:2348-60 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Yabas M, Jing W, Shafik S, Bröer S, Enders A. ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes. PLoS ONE. 2016;11:e0146774 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Lal G, Nakayama Y, Sethi A, Singh A, Burrell B, Kulkarni N, et al. Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance. Transplantation. 2015;99:1817-28 pubmed publisher
  • flow cytometry; mouse; fig s4
Wong E, Soni C, Chan A, Domeier P, Shwetank -, Abraham T, et al. B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance. J Immunol. 2015;194:4130-43 pubmed publisher
  • flow cytometry; mouse
Lee Chang C, Bodogai M, Moritoh K, Olkhanud P, Chan A, Croft M, et al. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014;124:1450-9 pubmed publisher
Kobayashi A, Ito A, Shirakawa I, Tamura A, Tomono S, Shindou H, et al. Dietary Supplementation With Eicosapentaenoic Acid Inhibits Plasma Cell Differentiation and Attenuates Lupus Autoimmunity. Front Immunol. 2021;12:650856 pubmed publisher
Xiao S, Bod L, Pochet N, KOTA S, Hu D, Madi A, et al. Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation. Cell Rep. 2020;32:107892 pubmed publisher
Piper C, Rosser E, Oleinika K, Nistala K, Krausgruber T, Rendeiro A, et al. Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells. Cell Rep. 2019;29:1878-1892.e7 pubmed publisher
Manni M, Gupta S, Ricker E, Chinenov Y, Park S, Shi M, et al. Regulation of age-associated B cells by IRF5 in systemic autoimmunity. Nat Immunol. 2018;19:407-419 pubmed publisher
Matsuba S, Yabe Wada T, Takeda K, Sato T, Suyama M, Takai T, et al. Identification of Secretory Leukoprotease Inhibitor As an Endogenous Negative Regulator in Allergic Effector Cells. Front Immunol. 2017;8:1538 pubmed publisher
Willis S, Tellier J, Liao Y, Trezise S, Light A, O Donnell K, et al. Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB. Nat Commun. 2017;8:1426 pubmed publisher
Schneppenheim J, Loock A, Hüttl S, Schweizer M, Lüllmann Rauch R, Oberg H, et al. The Influence of MHC Class II on B Cell Defects Induced by Invariant Chain/CD74 N-Terminal Fragments. J Immunol. 2017;199:172-185 pubmed publisher
Niss Arfelt K, Barington L, Benned Jensen T, Kubale V, Kovalchuk A, Daugvilaite V, et al. EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies. Blood. 2017;129:866-878 pubmed publisher
Craig V, Cogliatti S, Rehrauer H, Wündisch T, Muller A. Epigenetic silencing of microRNA-203 dysregulates ABL1 expression and drives Helicobacter-associated gastric lymphomagenesis. Cancer Res. 2011;71:3616-24 pubmed publisher
product information
Antigen :
CD23
Apps. Abbrev. :
Flow Cytometry, IP, Block, IHC-F
Cat # :
101602
Clone :
B3B4
Item :
Purified anti-mouse CD23
Isotype :
Rat IgG2a, κ
Other Names :
FcεRII, IgE Fc Receptor, BLAST-2, Ly-42, B6
Size :
500 μg
Price (USD) :
242 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
Complex of IgE with Fcε receptor isolated from the mouse B hybridoma cell line O1.2B2
Application Notes :
The B3B4 antibody is useful for blocking IgE activity in vivo . Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunofluorescence microscopy, in vitro and in vivo blocking of ligand binding 2-4 , immunohistochemical staining of acetone-fixed frozen sections 5 , and spatial biology (IBEX) 7,8 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA