product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD18
catalog :
101402
quantity :
500 μg
price :
115 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M18/2
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; fig 1c
Cunin P, Bouslama R, Machlus K, Martínez Bonet M, Lee P, Wactor A, et al. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. elife. 2019;8: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 7g
Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6c
Kraft S, Klemis V, Sens C, Lenhard T, Jacobi C, Samstag Y, et al. Identification and characterization of a unique role for EDB fibronectin in phagocytosis. J Mol Med (Berl). 2016;94:567-81 pubmed publisher
  • flow cytometry; mouse
Honjo K, Kubagawa Y, Suzuki Y, Takagi M, Ohno H, Bucy R, et al. Enhanced auto-antibody production and Mott cell formation in Fc?R-deficient autoimmune mice. Int Immunol. 2014;26:659-72 pubmed publisher
Horiguchi H, Kadomatsu T, Kurahashi R, Hara C, Miyata K, Baba M, et al. Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity. Genes Dev. 2019;33:1641-1656 pubmed publisher
Winter C, Silvestre Roig C, Ortega Gomez A, Lemnitzer P, Poelman H, Schumski A, et al. Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metab. 2018;28:175-182.e5 pubmed publisher
Gran S, Honold L, Fehler O, Zenker S, Eligehausen S, Kuhlmann M, et al. Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment in vivo. Theranostics. 2018;8:2407-2423 pubmed publisher
Saitoh S, Abe F, Kanno A, Tanimura N, Mori Saitoh Y, Fukui R, et al. TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells. Nat Commun. 2017;8:1592 pubmed publisher
Boras M, Volmering S, Bokemeyer A, Rossaint J, Block H, Bardel B, et al. Skap2 is required for ?2 integrin-mediated neutrophil recruitment and functions. J Exp Med. 2017;214:851-874 pubmed publisher
Quast T, Eppler F, Semmling V, Schild C, Homsi Y, Levy S, et al. CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration. Blood. 2011;118:1818-27 pubmed publisher
product information
Antigen :
CD18
Apps. Abbrev. :
Flow Cytometry, IHC, IP, Western Blotting
Cat # :
101402
Clone :
M18/2
Item :
Purified anti-mouse CD18
Isotype :
Rat IgG2a, κ
Other Names :
integrin β2, β2 integrin, ITGB2
Size :
500 μg
Price (USD) :
115 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
Mouse CTL glycoprotein
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 1,2 , Western blotting 1 , in vitro and in vivo blocking of tumor cells metastasis or stimulation of cell-adhesion 2-6 , and immunohistochemical staining 7 of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 101417-101422).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA