product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-mouse/human CD11b
catalog :
101226
quantity :
100 μg
price :
200 USD
clonality :
monoclonal
host :
rat
conjugate :
APC/Cy7
clone name :
M1/70
reactivity :
human, mouse, chimpanzee
application :
flow cytometry
more info or order :
citations: 128
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:2000; loading ...; fig s3b, s7c
Yu X, Liu H, Hamel K, Morvan M, Yu S, Leff J, et al. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. Nat Commun. 2020;11:264 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 1a
Jimeno R, Lebrusant Fernandez M, Margreitter C, LUCAS B, Veerapen N, Kelly G, et al. Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; 1:700; loading ...; fig ex2b
McAlpine C, Kiss M, Rattik S, He S, Vassalli A, Valet C, et al. Sleep modulates haematopoiesis and protects against atherosclerosis. Nature. 2019;566:383-387 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1s1a
Dosch M, Zindel J, Jebbawi F, Melin N, Sánchez Taltavull D, Stroka D, et al. Connexin-43-dependent ATP release mediates macrophage activation during sepsis. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 3a
Geng S, Chen K, Yuan R, Peng L, Maitra U, Diao N, et al. The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis. Nat Commun. 2016;7:13436 pubmed publisher
  • flow cytometry; mouse
Lammers K, Chieppa M, Liu L, Liu S, Omatsu T, Janka Junttila M, et al. Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1. PLoS ONE. 2015;10:e0138338 pubmed publisher
  • flow cytometry; mouse; fig 1
Li C, Cheng P, Liang M, Chen Y, Lu Q, Wang J, et al. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest. 2015;125:1509-22 pubmed publisher
  • flow cytometry; mouse; fig s12
Zimmermann M, Aguilera F, Castellucci M, Rossato M, Costa S, Lunardi C, et al. Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils. Nat Commun. 2015;6:6061 pubmed publisher
  • flow cytometry; mouse; fig 6
Fu C, Odegaard J, Hsieh M. Macrophages are required for host survival in experimental urogenital schistosomiasis. FASEB J. 2015;29:193-207 pubmed publisher
  • flow cytometry; mouse; fig 3a
Stoilova B, Kowenz Leutz E, Scheller M, Leutz A. Lymphoid to myeloid cell trans-differentiation is determined by C/EBP? structure and post-translational modifications. PLoS ONE. 2013;8:e65169 pubmed publisher
  • flow cytometry; mouse
Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed publisher
Choi E, Lee M, Song J, Kim K, Lee J, Yang J, et al. Fas mutation reduces obesity by increasing IL-4 and IL-10 expression and promoting white adipose tissue browning. Sci Rep. 2020;10:12001 pubmed publisher
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, et al. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. Cell Rep. 2020;31:107628 pubmed publisher
García Bonilla M, Ojeda Pérez B, Garcia Martin M, Muñoz Hernández M, Vitorica J, Jimenez S, et al. Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells. Stem Cell Res Ther. 2020;11:121 pubmed publisher
Cabal Hierro L, van Galen P, Prado M, Higby K, Togami K, Mowery C, et al. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020;11:1406 pubmed publisher
Saika A, Nagatake T, Kishino S, Park S, Honda T, Matsumoto N, et al. 17(S),18(R)-epoxyeicosatetraenoic acid generated by cytochrome P450 BM-3 from Bacillus megaterium inhibits the development of contact hypersensitivity via G-protein-coupled receptor 40-mediated neutrophil suppression. FASEB Bioadv. 2020;2:59-71 pubmed publisher
Yang M, Li C, Xiao Y, Guo Q, Huang Y, Su T, et al. Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation. Cell Prolif. 2020;53:e12784 pubmed publisher
Li Y, Elmén L, Segota I, Xian Y, Tinoco R, Feng Y, et al. Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth. Cell Rep. 2020;30:1753-1766.e6 pubmed publisher
Di Gioia M, Spreafico R, Springstead J, Mendelson M, Joehanes R, Levy D, et al. Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation. Nat Immunol. 2020;21:42-53 pubmed publisher
Ge Y, Gong M, Zadeh M, Li J, Abbott J, Li W, et al. Regulating colonic dendritic cells by commensal glycosylated large surface layer protein A to sustain gut homeostasis against pathogenic inflammation. Mucosal Immunol. 2020;13:34-46 pubmed publisher
Bhattacherjee A, Rodrigues E, Jung J, Luzentales Simpson M, Enterina J, Galleguillos D, et al. Repression of phagocytosis by human CD33 is not conserved with mouse CD33. Commun Biol. 2019;2:450 pubmed publisher
Wong E, Montoya B, Stotesbury C, Ferez M, Xu R, Sigal L. Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node. Cell Rep. 2019;29:3047-3059.e3 pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Nowak W, Grendas L, Sanmarco L, Estecho I, Arena Á, Eberhardt N, et al. Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR. EBioMedicine. 2019;50:290-305 pubmed publisher
Hoyer F, Naxerova K, Schloss M, Hulsmans M, Nair A, Dutta P, et al. Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. 2019;51:899-914.e7 pubmed publisher
Davis F, Schaller M, denDekker A, Joshi A, Kimball A, Evanoff H, et al. Sepsis Induces Prolonged Epigenetic Modifications in Bone Marrow and Peripheral Macrophages Impairing Inflammation and Wound Healing. Arterioscler Thromb Vasc Biol. 2019;39:2353-2366 pubmed publisher
Larson Casey J, Vaid M, Gu L, He C, Cai G, Ding Q, et al. Increased flux through the mevalonate pathway mediates fibrotic repair without injury. J Clin Invest. 2019;129:4962-4978 pubmed publisher
Yoshimi A, Lin K, Wiseman D, Rahman M, Pastore A, Wang B, et al. Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis. Nature. 2019;574:273-277 pubmed publisher
Kashyap A, Fernandez Rodriguez L, Zhao Y, Monaco G, Trefny M, Yoshida N, et al. GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses. Cell Rep. 2019;28:3367-3380.e8 pubmed publisher
Viny A, Bowman R, Liu Y, Lavallée V, Eisman S, Xiao W, et al. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019;25:682-696.e8 pubmed publisher
Harel M, Ortenberg R, Varanasi S, Mangalhara K, Mardamshina M, Markovits E, et al. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Cell. 2019;179:236-250.e18 pubmed publisher
Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher
Pietronigro E, Zenaro E, Bianca V, Dusi S, Terrabuio E, Iannoto G, et al. Blockade of α4 integrins reduces leukocyte-endothelial interactions in cerebral vessels and improves memory in a mouse model of Alzheimer's disease. Sci Rep. 2019;9:12055 pubmed publisher
Xiong X, Kuang H, Ansari S, Liu T, Gong J, Wang S, et al. Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. Mol Cell. 2019;75:644-660.e5 pubmed publisher
McKenzie M, Ghisi M, Oxley E, Ngo S, Cimmino L, Esnault C, et al. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. Cell Stem Cell. 2019;25:258-272.e9 pubmed publisher
Carestia A, Mena H, Olexen C, Ortiz Wilczyñski J, Negrotto S, Errasti A, et al. Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice. Cell Rep. 2019;28:896-908.e5 pubmed publisher
Mariani S, Li Z, Rice S, Krieg C, Fragkogianni S, Robinson M, et al. Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells. Immunity. 2019;: pubmed publisher
Casulli J, Fife M, Houston S, Rossi S, Dow J, Williamson E, et al. CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality. Nat Commun. 2019;10:2121 pubmed publisher
Goldstein J, Tabebordbar M, Zhu K, Wang L, Messemer K, Peacker B, et al. In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep. 2019;27:1254-1264.e7 pubmed publisher
Fachi J, Felipe J, Pral L, da Silva B, Corrêa R, de Andrade M, et al. Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism. Cell Rep. 2019;27:750-761.e7 pubmed publisher
Delás M, Jackson B, Kovacević T, Vangelisti S, Munera Maravilla E, Wild S, et al. lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation. Cell Rep. 2019;27:719-729.e6 pubmed publisher
Parlet C, Kavanaugh J, Crosby H, Raja H, El Elimat T, Todd D, et al. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Rep. 2019;27:187-198.e6 pubmed publisher
Codina A, Renauer P, Wang G, Chow R, Park J, Ye H, et al. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Syst. 2019;8:136-151.e7 pubmed publisher
Mathur R, Alam M, Zhao X, Liao Y, Shen J, Morgan S, et al. Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis. Mucosal Immunol. 2019;12:612-623 pubmed publisher
Miragaia R, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy A, et al. Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation. Immunity. 2019;50:493-504.e7 pubmed publisher
Yin S, Gambe R, Sun J, Martinez A, Cartun Z, Regis F, et al. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer Cell. 2019;35:283-296.e5 pubmed publisher
Martínez López M, Iborra S, Conde Garrosa R, Mastrangelo A, Danne C, Mann E, et al. Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity. Immunity. 2019;50:446-461.e9 pubmed publisher
Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, et al. Liver-Resident NK Cells Control Antiviral Activity of Hepatic T Cells via the PD-1-PD-L1 Axis. Immunity. 2019;50:403-417.e4 pubmed publisher
Yoshida H, Lareau C, Ramirez R, Rose S, Maier B, Wroblewska A, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019;176:897-912.e20 pubmed publisher
Luo H, Mu W, Karki R, Chiang H, Mohrin M, Shin J, et al. Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. Cell Rep. 2019;26:945-954.e4 pubmed publisher
Qiao S, Qian Y, Xu G, Luo Q, Zhang Z. Long-term characterization of activated microglia/macrophages facilitating the development of experimental brain metastasis through intravital microscopic imaging. J Neuroinflammation. 2019;16:4 pubmed publisher
Keklikoglou I, Cianciaruso C, Güç E, Squadrito M, Spring L, Tazzyman S, et al. Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol. 2019;21:190-202 pubmed publisher
Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen J, et al. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. Cell Metab. 2019;29:443-456.e5 pubmed publisher
Chen Z, Amro E, Becker F, Holzer M, Rasa S, Njeru S, et al. Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation. J Exp Med. 2019;216:152-175 pubmed publisher
Wang H, Lin X, Luo Y, Sun S, Tian X, Sun Y, et al. α-PD-L1 mAb enhances the abscopal effect of hypo-fractionated radiation by attenuating PD-L1 expression and inducing CD8+ T-cell infiltration. Immunotherapy. 2019;11:101-118 pubmed publisher
Edgar L, Kawasaki N, Nycholat C, Paulson J. Targeted Delivery of Antigen to Activated CD169+ Macrophages Induces Bias for Expansion of CD8+ T Cells. Cell Chem Biol. 2019;26:131-136.e4 pubmed publisher
Li B, Zhang S, Huang N, Chen H, Wang P, Yang J, et al. CCL9/CCR1 induces myeloid‑derived suppressor cell recruitment to the spleen in a murine H22 orthotopic hepatoma model. Oncol Rep. 2019;41:608-618 pubmed publisher
Cho S, Vardi A, Platt N, Futerman A. Absence of infiltrating peripheral myeloid cells in the brains of mouse models of lysosomal storage disorders. J Neurochem. 2019;148:625-638 pubmed publisher
Säwén P, Eldeeb M, Erlandsson E, Kristiansen T, Laterza C, Kokaia Z, et al. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging. elife. 2018;7: pubmed publisher
Celik H, Koh W, Kramer A, Ostrander E, Mallaney C, Fisher D, et al. JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells. Cancer Cell. 2018;34:741-756.e8 pubmed publisher
Li C, Xiao Y, Yang M, Su T, Sun X, Guo Q, et al. Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. J Clin Invest. 2018;128:5251-5266 pubmed publisher
Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher
Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, et al. Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018;49:490-503.e4 pubmed publisher
Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, et al. Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression. Cell Metab. 2018;28:243-255.e5 pubmed publisher
Nagatake T, Suzuki H, Hirata S, Matsumoto N, Wada Y, Morimoto S, et al. Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice. Int Immunol. 2018;30:471-481 pubmed publisher
Lino A, Dang V, Lampropoulou V, Welle A, Joedicke J, Pohar J, et al. LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018;49:120-133.e9 pubmed publisher
Kim M, Galan C, Hill A, Wu W, Fehlner Peach H, Song H, et al. Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses. Immunity. 2018;49:151-163.e5 pubmed publisher
Liu S, Xia Q, Wu X, Sun F, Hu Q, Wu J, et al. Stimulator of Interferon Genes in Classical Dendritic Cells Controls Mucosal Th17 Responses to Cyclic Dinucleotides for Host Defenses Against Microbial Infections in Gut. Front Immunol. 2018;9:1085 pubmed publisher
Niknam S, Barsoumian H, Schoenhals J, Jackson H, Yanamandra N, Caetano M, et al. Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti-PD1-Resistant Lung Tumor Model. Clin Cancer Res. 2018;24:5735-5743 pubmed publisher
Filipello F, Morini R, Corradini I, Zerbi V, Canzi A, Michalski B, et al. The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity. Immunity. 2018;48:979-991.e8 pubmed publisher
Perry J, Russler Germain E, Zhou Y, Purtha W, Cooper M, Choi J, et al. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018;48:923-936.e4 pubmed publisher
Li A, Barsoumian H, Schoenhals J, Cushman T, Caetano M, Wang X, et al. Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells. Cancer Lett. 2018;431:54-63 pubmed publisher
Zhang K, Riba A, Nietschke M, Torow N, Repnik U, Pütz A, et al. Minimal SPI1-T3SS effector requirement for Salmonella enterocyte invasion and intracellular proliferation in vivo. PLoS Pathog. 2018;14:e1006925 pubmed publisher
Mamedov M, Scholzen A, Nair R, Cumnock K, Kenkel J, Oliveira J, et al. A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence. Immunity. 2018;48:350-363.e7 pubmed publisher
Soncin I, Sheng J, Chen Q, Foo S, Duan K, Lum J, et al. The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma. Nat Commun. 2018;9:582 pubmed publisher
Syed I, Lee J, Moraes Vieira P, Donaldson C, Sontheimer A, Aryal P, et al. Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metab. 2018;27:419-427.e4 pubmed publisher
Nagatake T, Shiogama Y, Inoue A, Kikuta J, Honda T, Tiwari P, et al. The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques. J Allergy Clin Immunol. 2018;142:470-484.e12 pubmed publisher
Zhao J, Zhou X, Tang Q, Yu R, Yu S, Long Y, et al. BMAL1 Deficiency Contributes to Mandibular Dysplasia by Upregulating MMP3. Stem Cell Reports. 2018;10:180-195 pubmed publisher
Duarte D, Hawkins E, Akinduro O, Ang H, De Filippo K, Kong I, et al. Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML. Cell Stem Cell. 2018;22:64-77.e6 pubmed publisher
Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, et al. Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity. Cancer Cell. 2018;33:44-59.e8 pubmed publisher
Kleppe M, Koche R, Zou L, van Galen P, Hill C, Dong L, et al. Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. Cancer Cell. 2018;33:29-43.e7 pubmed publisher
Crane A, Brubaker W, Johansson J, Trigunaite A, Ceballos J, Bradt B, et al. Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: 2. Relationship to amyloid β immunotherapy. Alzheimers Dement. 2018;14:243-252 pubmed publisher
Clarke F, Jordan C, Gutiérrez Martínez E, Bibby J, Sanchez Blanco C, Cornish G, et al. Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells. PLoS ONE. 2017;12:e0186625 pubmed publisher
Sia J, Bizzell E, Madan Lala R, Rengarajan J. Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection. PLoS Pathog. 2017;13:e1006530 pubmed publisher
Sweet R, Nickerson K, Cullen J, Wang Y, Shlomchik M. B Cell-Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B Cell Immune Responses. J Immunol. 2017;199:885-893 pubmed publisher
Thiriot A, Perdomo C, Cheng G, Novitzky Basso I, McArdle S, Kishimoto J, et al. Differential DARC/ACKR1 expression distinguishes venular from non-venular endothelial cells in murine tissues. BMC Biol. 2017;15:45 pubmed publisher
Mishra B, Lovewell R, Olive A, Zhang G, Wang W, Eugenin E, et al. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. Nat Microbiol. 2017;2:17072 pubmed publisher
Hulsmans M, Clauss S, Xiao L, Aguirre A, King K, Hanley A, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169:510-522.e20 pubmed publisher
Lee M, McCubbin J, Christensen A, Poole D, Rajasekhar P, Lieu T, et al. G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease. J Immunol. 2017;198:3565-3575 pubmed publisher
Ano Y, Dohata A, Taniguchi Y, Hoshi A, Uchida K, Takashima A, et al. Iso-α-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease. J Biol Chem. 2017;292:3720-3728 pubmed publisher
Clement M, Marsden M, Stacey M, Abdul Karim J, Gimeno Brias S, Costa Bento D, et al. Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence. PLoS Pathog. 2016;12:e1006050 pubmed publisher
Kirschbaum K, Sonner J, Zeller M, Deumelandt K, Bode J, Sharma R, et al. In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis. Proc Natl Acad Sci U S A. 2016;113:13227-13232 pubmed
Diao N, Zhang Y, Chen K, Yuan R, Lee C, Geng S, et al. Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis. Sci Rep. 2016;6:34672 pubmed publisher
Snell L, Osokine I, Yamada D, de la Fuente J, Elsaesser H, Brooks D. Overcoming CD4 Th1 Cell Fate Restrictions to Sustain Antiviral CD8 T Cells and Control Persistent Virus Infection. Cell Rep. 2016;16:3286-3296 pubmed publisher
Kurkewich J, Klopfenstein N, Hallas W, Wood C, Sattler R, Das C, et al. Arid3b Is Critical for B Lymphocyte Development. PLoS ONE. 2016;11:e0161468 pubmed publisher
Billroth MacLurg A, Ford J, Rosenberg A, Miller J, Fowell D. Regulatory T Cell Numbers in Inflamed Skin Are Controlled by Local Inflammatory Cues That Upregulate CD25 and Facilitate Antigen-Driven Local Proliferation. J Immunol. 2016;197:2208-18 pubmed publisher
Palamides P, Jodeleit H, Föhlinger M, Beigel F, Herbach N, Mueller T, et al. A mouse model for ulcerative colitis based on NOD-scid IL2R ?null mice reconstituted with peripheral blood mononuclear cells from affected individuals. Dis Model Mech. 2016;9:985-97 pubmed publisher
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
Denk F, Crow M, Didangelos A, Lopes D, McMahon S. Persistent Alterations in Microglial Enhancers in a Model of Chronic Pain. Cell Rep. 2016;15:1771-81 pubmed publisher
Yabas M, Jing W, Shafik S, Bröer S, Enders A. ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes. PLoS ONE. 2016;11:e0146774 pubmed publisher
Wu X, Yang Y, Li W, Cheng Y, Li X, Huang C, et al. Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease. Sci Rep. 2016;6:18685 pubmed publisher
Ferreira R, Pinto Ribeiro I, Wen X, Marcos Pinto R, Dinis Ribeiro M, Carneiro F, et al. Helicobacter pylori cagA Promoter Region Sequences Influence CagA Expression and Interleukin 8 Secretion. J Infect Dis. 2016;213:669-73 pubmed publisher
Tanaka Y, Inoue Yokoo T, Kulkeaw K, Yanagi Mizuochi C, Shirasawa S, Nakanishi Y, et al. Embryonic Hematopoietic Progenitor Cells Reside in Muscle before Bone Marrow Hematopoiesis. PLoS ONE. 2015;10:e0138621 pubmed publisher
Ermert D, Shaughnessy J, Joeris T, Kaplan J, Pang C, Kurt Jones E, et al. Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors. PLoS Pathog. 2015;11:e1005043 pubmed publisher
Eastman A, He X, Qiu Y, Davis M, Vedula P, Lyons D, et al. Cryptococcal heat shock protein 70 homolog Ssa1 contributes to pulmonary expansion of Cryptococcus neoformans during the afferent phase of the immune response by promoting macrophage M2 polarization. J Immunol. 2015;194:5999-6010 pubmed publisher
Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, et al. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015;212:905-25 pubmed publisher
Price P, Bánki Z, Scheideler A, Stoiber H, Verschoor A, Sutter G, et al. Complement component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia virus Ankara. J Immunol. 2015;194:1164-8 pubmed publisher
Krueger K, Costa M, Du H, Feldman B. Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells. Stem Cell Reports. 2014;3:1147-58 pubmed publisher
Ashok A, Rai N, Tripathi S, Bandyopadhyay S. Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats. Toxicol Sci. 2015;143:64-80 pubmed publisher
Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, et al. Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses. elife. 2014;3:e04177 pubmed publisher
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product information
Antigen :
CD11b
Apps. Abbrev. :
Flow Cytometry
Cat # :
101226
Clone :
M1/70
Item :
APC/Cyanine7 anti-mouse/human CD11b
Isotype :
Rat IgG2b, κ
Other Names :
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Size :
100 μg
Price (USD) :
200 USD
Reactivity :
Mouse, Human, Cross-Reactivity: Cynomolgus, Rhesus, Baboon, Chimpanzee,Rabbit (Lapine)
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC_CYANINE7
Immunogen :
C57BL/10 splenocytes
Application Notes :
Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for relevant formats of this clone) include: immunoprecipitation 1,4 , in vitro blocking 3,9,12 , depletion 2,8 , immunofluorescence microscopy 6,7,10 , and immunohistochemistry of acetone-fixed frozen sections 5,11-13 . For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA