APC anti-mouse CD11a | BioLegend 101120 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-mouse CD11a

catalog :

101120

quantity :

100 μg

price :

249 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

M17/4

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 3f	McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
	Wang Y, Song W, Xu Q, Liu Y, Liu H, Guo R, et al. Adjuvant DNA vaccine pNMM promotes enhanced specific immunity and anti-tumor effects. Hum Vaccin Immunother. 2023;19:2202127 pubmed publisher
	Green W, Al Shaer A, Shi Q, Gowdy K, Maciver N, Milner J, et al. Metabolic and functional impairment of CD8+ T cells from the lungs of influenza-infected obese mice. J Leukoc Biol. 2022;111:147-159 pubmed publisher
	Pradhan K, Geng S, Zhang Y, Lin R, Li L. TRAM-Related TLR4 Pathway Antagonized by IRAK-M Mediates the Expression of Adhesion/Coactivating Molecules on Low-Grade Inflammatory Monocytes. J Immunol. 2021;206:2980-2988 pubmed publisher
	Panagiotakopoulou V, Ivanyuk D, De Cicco S, Haq W, Arsic A, Yu C, et al. Interferon-γ signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells. Nat Commun. 2020;11:5163 pubmed publisher
	Yang L, Han Y, Nilsson Payant B, Gupta V, Wang P, Duan X, et al. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell Stem Cell. 2020;27:125-136.e7 pubmed publisher
	Hodgins B, Pillet S, Landry N, Ward B. Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after challenge. Immun Ageing. 2019;16:27 pubmed publisher
	Zhu Y, Padgett L, Dinh H, Marcovecchio P, Blatchley A, Wu R, et al. Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow. Cell Rep. 2018;24:2329-2341.e8 pubmed publisher
	Verhagen J, Wraith D. Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3? Treg cells. J Immunol Methods. 2014;414:58-64 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Cat # :

101120

Clone :

M17/4

Item :

APC anti-mouse CD11a

Isotype :

Rat IgG2a, κ

Other Names :

αL integrin, LFA-1 α subunit, Ly-15, Ly-21, ITGAL

Size :

100 μg

Price (USD) :

249 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

C57BL/6 mouse splenic secondary cytotoxic T cells

Application Notes :

The M17/4 antibody can block CD11a-mediated cellular adhesion. Additional reported applications of this antibody (for the relevant formats) include: immunoprecipitation^1,2, in vitro blocking of cell-cell adhesion^1,2 and FOXP3 expression^5, and immunohistochemical staining of acetone-fixed frozen sections^3. The M17/4 antibody does not block the binding of 2D7 antibody (Cat. No. 101002) to CD11a. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 101110). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101118) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage