product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse CD11a
catalog :
101106
quantity :
500 μg
price :
297 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
M17/4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 3c
Misumi I, Starmer J, Uchimura T, Beck M, Magnuson T, Whitmire J. Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection. Cell Rep. 2019;27:514-524.e5 pubmed publisher
  • flow cytometry; mouse; fig 5
Edwards C, Best S, Gun S, Claser C, James K, de Oca M, et al. Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection. Eur J Immunol. 2015;45:130-41 pubmed publisher
Pack A, Schwartzhoff P, Zacharias Z, Fernández Ruiz D, Heath W, Gurung P, et al. Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity. Cell Rep. 2021;36:109586 pubmed publisher
Pardy R, Valbon S, Cordeiro B, Krawczyk C, Richer M. An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways. Nat Commun. 2021;12:4051 pubmed publisher
Mandal R, Denny J, Namazzi R, Opoka R, Datta D, John C, et al. Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection. Cell Rep. 2021;35:109094 pubmed publisher
Waide M, Polidoro R, Powell W, Denny J, Kos J, Tieri D, et al. Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections. Cell Rep. 2020;33:108503 pubmed publisher
Martin M, Sompallae R, Winborn C, Harty J, Badovinac V. Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross. Cell Rep. 2020;31:107508 pubmed publisher
Kumar R, Bunn P, Singh S, Ng S, Montes De Oca M, de Labastida Rivera F, et al. Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis. Cell Rep. 2020;30:2512-2525.e9 pubmed publisher
Mamedov M, Scholzen A, Nair R, Cumnock K, Kenkel J, Oliveira J, et al. A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence. Immunity. 2018;48:350-363.e7 pubmed publisher
Sebina I, James K, Soon M, Fogg L, Best S, Labastida Rivera F, et al. IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection. PLoS Pathog. 2016;12:e1005999 pubmed publisher
Montes De Oca M, Kumar R, de Labastida Rivera F, Amante F, Sheel M, Faleiro R, et al. Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology. PLoS Pathog. 2016;12:e1005398 pubmed publisher
Halford W, Geltz J, Messer R, Hasenkrug K. Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2. PLoS ONE. 2015;10:e0145228 pubmed publisher
Verhagen J, Wraith D. Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3? Treg cells. J Immunol Methods. 2014;414:58-64 pubmed publisher
Coquery C, Wade N, Loo W, Kinchen J, Cox K, Jiang C, et al. Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice. PLoS ONE. 2014;9:e102284 pubmed publisher
Gurung P, Rai D, Condotta S, Babcock J, Badovinac V, Griffith T. Immune unresponsiveness to secondary heterologous bacterial infection after sepsis induction is TRAIL dependent. J Immunol. 2011;187:2148-54 pubmed publisher
Gültner S, Kuhlmann T, Hesse A, Weber J, Riemer C, Baier M, et al. Reduced Treg frequency in LFA-1-deficient mice allows enhanced T effector differentiation and pathology in EAE. Eur J Immunol. 2010;40:3403-12 pubmed publisher
product information
Antigen :
CD11a
Apps. Abbrev. :
FC
Cat # :
101106
Clone :
M17/4
Item :
FITC anti-mouse CD11a
Isotype :
Rat IgG2a, κ
Other Names :
αL integrin, LFA-1 α subunit, Ly-15, Ly-21, ITGAL
Size :
500 μg
Price (USD) :
297 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
FITC
Immunogen :
C57BL/6 mouse splenic secondary cytotoxic T cells
Application Notes :
The M17/4 antibody can block CD11a-mediated cellular adhesion. Additional reported applications of this antibody (for the relevant formats) include: immunoprecipitation^1,2, in vitro blocking of cell-cell adhesion^1,2 and FOXP3 expression^5, and immunohistochemical staining of acetone-fixed frozen sections^3. The M17/4 antibody does not block the binding of 2D7 antibody (Cat. No. 101002) to CD11a. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 101110). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101118) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA