Biotin anti-mouse CD11a | BioLegend 101103 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Biotin anti-mouse CD11a

catalog :

101103

quantity :

50 μg

price :

65 USD

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

M17/4

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Chen J, Miyanishi M, Wang S, Yamazaki S, Sinha R, Kao K, et al. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 2016;530:223-7 pubmed publisher
	Anthony S, Van Braeckel Budimir N, Moioffer S, Van de Wall S, Shan Q, Vijay R, et al. Protective function and durability of mouse lymph node-resident memory CD8+ T cells. elife. 2021;10: pubmed publisher
	Khan K, Ponce de León J, Benguigui M, Xu P, Chow A, Cruz Munoz W, et al. Immunostimulatory and anti-tumor metronomic cyclophosphamide regimens assessed in primary orthotopic and metastatic murine breast cancer. NPJ Breast Cancer. 2020;6:29 pubmed publisher
	Chen L, Strohmeier V, He Z, Deshpande M, Catalan Dibene J, Durum S, et al. Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23. Nat Commun. 2019;10:4517 pubmed publisher
	Majer O, Liu B, Kreuk L, Krogan N, Barton G. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature. 2019;575:366-370 pubmed publisher
	Vinaik R, Barayan D, Abdullahi A, Jeschke M. NLRP3 inflammasome mediates white adipose tissue browning after burn. Am J Physiol Endocrinol Metab. 2019;317:E751-E759 pubmed publisher
	Feng L, Murugan M, Bosco D, Liu Y, Peng J, Worrell G, et al. Microglial proliferation and monocyte infiltration contribute to microgliosis following status epilepticus. Glia. 2019;67:1434-1448 pubmed publisher
	Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, et al. Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115. Virulence. 2019;10:248-259 pubmed publisher
	Kang S, Keam B, Ahn Y, Park H, Kim M, Kim T, et al. Inhibition of MEK with trametinib enhances the efficacy of anti-PD-L1 inhibitor by regulating anti-tumor immunity in head and neck squamous cell carcinoma. Oncoimmunology. 2019;8:e1515057 pubmed publisher
	Guiducci E, Lemberg C, Küng N, Schraner E, Theocharides A, LeibundGut Landmann S. Candida albicans-Induced NETosis Is Independent of Peptidylarginine Deiminase 4. Front Immunol. 2018;9:1573 pubmed publisher
	Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed publisher
	Taki M, Abiko K, Baba T, Hamanishi J, Yamaguchi K, Murakami R, et al. Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation. Nat Commun. 2018;9:1685 pubmed publisher
	Shin J, Fukuhara A, Onodera T, Kita S, Yokoyama C, Otsuki M, et al. SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes. Diabetes. 2018;67:1068-1078 pubmed publisher
	Hoves S, Ooi C, Wolter C, Sade H, Bissinger S, Schmittnaegel M, et al. Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity. J Exp Med. 2018;215:859-876 pubmed publisher
	Verhagen J, Wraith D. Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3? Treg cells. J Immunol Methods. 2014;414:58-64 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Cat # :

101103

Clone :

M17/4

Item :

Biotin anti-mouse CD11a

Isotype :

Rat IgG2a, κ

Other Names :

αL integrin, LFA-1 α subunit, Ly-15, Ly-21, ITGAL

Size :

50 μg

Price (USD) :

65 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BIOTIN

Immunogen :

C57BL/6 mouse splenic secondary cytotoxic T cells

Application Notes :

The M17/4 antibody can block CD11a-mediated cellular adhesion. Additional reported applications of this antibody (for the relevant formats) include: immunoprecipitation^1,2, in vitro blocking of cell-cell adhesion^1,2 and FOXP3 expression^5, and immunohistochemical staining of acetone-fixed frozen sections^3. The M17/4 antibody does not block the binding of 2D7 antibody (Cat. No. 101002) to CD11a. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 101110). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101118) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage