product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse CD8a
catalog :
100803
quantity :
50 μg
price :
94 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
5H10-1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 16
Reference
Gon xe7 alves R, Couto J, Ferreirinha P, Costa J, Silv xe9 rio D, Silva M, et al. SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice. iScience. 2023;26:105972 pubmed publisher
Jin S, Yoo Y, Shin H, Kim S, Lee S, Lee C, et al. A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion. Nat Nanotechnol. 2023;18:390-402 pubmed publisher
Wu J, Li G, Li D, Zhou J, Dong Z, Jiang P. Detection of CD8+ T cell-mediated immune responses to bacterial infection in mice. STAR Protoc. 2021;2:101022 pubmed publisher
Shin J, Lee S, Gharbi A, Jung I, Park Y. IOX1 impedes host inflammation in imiquimod-triggered psoriasis. Heliyon. 2021;7:e08433 pubmed publisher
Shrivastava T, Singh B, Rizvi Z, Verma R, Goswami S, Vishwakarma P, et al. Comparative Immunomodulatory Evaluation of the Receptor Binding Domain of the SARS-CoV-2 Spike Protein; a Potential Vaccine Candidate Which Imparts Potent Humoral and Th1 Type Immune Response in a Mouse Model. Front Immunol. 2021;12:641447 pubmed publisher
Derada Troletti C, Enzmann G, Chiurchiù V, Kamermans A, Tietz S, Norris P, et al. Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome. Cell Rep. 2021;35:109201 pubmed publisher
McNamara H, Idris A, Sutton H, Vistein R, Flynn B, Cai Y, et al. Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response. Cell Host Microbe. 2020;: pubmed publisher
Moutuou M, Gauthier S, Chen N, LeBoeuf D, Guimond M. Studying Peripheral T Cell Homeostasis in Mice: A Concise Technical Review. Methods Mol Biol. 2020;2111:267-283 pubmed publisher
Wang F, Tsai J, Davis J, Chau B, Dong J, West S, et al. Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models. MAbs. 2020;12:1685350 pubmed publisher
Suhail A, Rizvi Z, Mujagond P, Ali S, Gaur P, Singh M, et al. DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells. Cell Rep. 2019;29:3522-3538.e7 pubmed publisher
Cá B, Fonseca K, Sousa J, Maceiras A, Machado D, Sanca L, et al. Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum. Front Microbiol. 2019;10:2102 pubmed publisher
Wu J, Ma S, Sandhoff R, Ming Y, Hotz Wagenblatt A, Timmerman V, et al. Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness. Immunity. 2019;50:1218-1231.e5 pubmed publisher
Bhatt K, Machado H, Osório N, Sousa J, Cardoso F, Magalhães C, et al. A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tuberculosis. mSphere. 2018;3: pubmed publisher
Nakajima A, Negishi N, Tsurui H, Kadowaki Ohtsuji N, Maeda K, Nanno M, et al. Commensal bacteria regulate thymic Aire expression. PLoS ONE. 2014;9:e105904 pubmed publisher
Korrer M, Zhang Y, Routes J. Possible role of arginase-1 in concomitant tumor immunity. PLoS ONE. 2014;9:e91370 pubmed publisher
Johannsen A, Genolet R, Legler D, Luther S, Luescher I. Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice. J Immunol. 2010;185:3445-55 pubmed publisher
product information
Antigen :
CD8alpha
Apps. Abbrev. :
FC
Cat # :
100803
Clone :
5H10-1
Item :
FITC anti-mouse CD8a
Isotype :
Rat (SD) IgG2b, λ
Other Names :
T8, Lyt2, Ly-2
Size :
50 μg
Price (USD) :
94 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
FITC
Immunogen :
Concanavalin A-stimulated BALB/c splenic T cells
Application Notes :
Additional reported applications (for the relevant formats) include: partial inhibition of T-cell responses to IL-2 and cytotoxic induction of splenic T cells^1, and immunohistochemistry^2 of acetone-fixed frozen sections. The 5H10-1 antibody competes with 53-6.7 antibody (Cat. No. 100702) for binding to thymocytes^1.Clone 5H10-1 is not recommended for immunohistochemistry of formalin-fixed paraffin sections.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA