Spark Violet™ 538 anti-mouse CD4 | BioLegend 100486 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Spark Violet™ 538 anti-mouse CD4

catalog :

100486

quantity :

100 μg

price :

370 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GK1.5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4e	Shi Z, Takeuchi T, Nakanishi Y, Kato T, Beck K, Nagata R, et al. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Front Immunol. 2022;13:903459 pubmed publisher
flow cytometry; mouse; loading ...; fig s1a, 4c	Aiken T, Erbe A, Zebertavage L, Komjathy D, Feils A, Rodriguez M, et al. Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma. J Immunother Cancer. 2022;10: pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Flow Cytometry

Cat # :

100486

Clone :

GK1.5

Item :

Spark Violet™ 538 anti-mouse CD4

Isotype :

Rat IgG2b, κ

Other Names :

L3T4, T4

Size :

100 μg

Price (USD) :

370 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

SPKVL_538

Immunogen :

Mouse CTL clone V4

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of CD4 + T cell activation 1,4,11 , thymocyte costimulation 3 , in vitro and in vivo depletion 2,5-8 , blocking of egg-sperm cell adhesion 1,4 , immunohistochemical staining of acetone-fixed frozen sections 9,10 , immunoprecipitation 1,2 , and spatial biology (IBEX) 12,13 . The GK1.5 antibody is able to block CD4 mediated cell adhesion and T cell activation. Binding of GK1.5 antibody to CD4 T cells can be blocked by RM4-5 antibody, but not RM4-4 antibody. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 100442) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).

more info or order :

BioLegend product webpage