Brilliant Violet 650™ anti-mouse CD4 | BioLegend 100469 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 650™ anti-mouse CD4

catalog :

100469

quantity :

50 μg

price :

273 USD

clonality :

monoclonal

host :

rat

conjugate :

BV650

clone name :

GK1.5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...	Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
	van Os B, Kusters P, den Toom M, Beckers L, Van Tiel C, Vos W, et al. Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis. Front Cardiovasc Med. 2023;10:1171764 pubmed publisher
	Liu J, Bu X, Chu C, Dai X, Asara J, Sicinski P, et al. PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity. Nat Commun. 2023;14:2806 pubmed publisher
	Huang T, Wu W, Wu J, Tan Y, Zhang M, Long H, et al. Perfluorocarbon nanodrug induced oxygen self-enriching sonodynamic therapy improves cancer immunotherapy after insufficient radiofrequency ablation. Front Immunol. 2023;14:1124152 pubmed publisher
	Glaubitz J, Wilden A, Frost F, Ameling S, Homuth G, Mazloum H, et al. Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis. Gut. 2023;72:1355-1369 pubmed publisher
	Abdelfattah N, Kumar P, Wang C, Leu J, Flynn W, Gao R, et al. Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. Nat Commun. 2022;13:767 pubmed publisher
	Lee A, Scott M, Wimmers F, Arunachalam P, Luo W, Fox C, et al. A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice. Nat Commun. 2022;13:549 pubmed publisher
	Dai X, Bu X, Gao Y, Guo J, Hu J, Jiang C, et al. Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade. Mol Cell. 2021;81:2317-2331.e6 pubmed publisher
	Mathewson N, Ashenberg O, Tirosh I, Gritsch S, Perez E, Marx S, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. 2021;184:1281-1298.e26 pubmed publisher
	Covarrubias A, Kale A, Perrone R, Lopez Dominguez J, Pisco A, Kasler H, et al. Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. Nat Metab. 2020;2:1265-1283 pubmed publisher
	Gao Y, Nihira N, Bu X, Chu C, Zhang J, Kolodziejczyk A, et al. Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy. Nat Cell Biol. 2020;22:1064-1075 pubmed publisher
	Yang J, Wang Z, Cai H, Yuan L, Hu M, Wu M, et al. Sex Differences in Neuropathology and Cognitive Behavior in APP/PS1/tau Triple-Transgenic Mouse Model of Alzheimer's Disease. Neurosci Bull. 2018;34:736-746 pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Cat # :

100469

Clone :

GK1.5

Item :

Brilliant Violet 650™ anti-mouse CD4

Isotype :

Rat IgG2b, κ

Other Names :

L3T4, T4

Size :

50 μg

Price (USD) :

273 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV650

Immunogen :

Mouse CTL clone V4

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of CD4^+ T cell activation^1,4,11, thymocyte costimulation^3, in vitro and in vivo depletion^2,5-8, blocking of egg-sperm cell adhesion^1,4, immunohistochemical staining of acetone-fixed frozen sections^9,10, immunoprecipitation^1,2, and spatial biology (IBEX)^12,13. The GK1.5 antibody is able to block CD4 mediated cell adhesion and T cell activation. Binding of GK1.5 antibody to CD4 T cells can be blocked by RM4-5 antibody, but not RM4-4 antibody. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 100442) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin < 0.01 EU/µg).;

more info or order :

BioLegend product webpage