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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 700 anti-mouse CD3
catalog :
100215
quantity :
25 μg
price :
85 USD
clonality :
monoclonal
host :
rat
conjugate :
AF700
clone name :
17A2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 37
Reference
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Hirai T, Zenke Y, Yang Y, Bartholin L, Beura L, Masopust D, et al. Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells. Immunity. 2019;50:1249-1261.e5 pubmed publisher
Miska J, Lee Chang C, Rashidi A, Muroski M, Chang A, Lopez Rosas A, et al. HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma. Cell Rep. 2019;27:226-237.e4 pubmed publisher
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product information
Antigen :
CD3
Apps. Abbrev. :
Flow Cytometry
Cat # :
100215
Clone :
17A2
Item :
Alexa Fluor® 700 anti-mouse CD3
Isotype :
Rat IgG2b, κ
Other Names :
T cell antigen receptor complex, T3
Size :
25 μg
Price (USD) :
85 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A700
Immunogen :
γδTCR-positive T-T hybridoma D1
Application Notes :
The 17A2 antibody recognizes ε/γ (but not ε/δ) of the CD3 complex. The 17A2 antibody can induce T cell activation and has been reported to deplete CD3 + cells in vivo . Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , complement-mediated cytotoxicity 1,3 , immunohistochemical staining of acetone-fixed frozen sections 1,4 , in vitro stimulation of T cells 1 and depletion of CD3 + cells in vivo 2 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA