product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse CD3
catalog :
100209
quantity :
100 μg
price :
195 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
17A2
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 19
Reference
Luck H, Khan S, Kim J, Copeland J, Revelo X, Tsai S, et al. Gut-associated IgA+ immune cells regulate obesity-related insulin resistance. Nat Commun. 2019;10:3650 pubmed publisher
Bárcena C, Aran G, Perea L, Sanjurjo L, Téllez É, Oncins A, et al. CD5L is a pleiotropic player in liver fibrosis controlling damage, fibrosis and immune cell content. EBioMedicine. 2019;43:513-524 pubmed publisher
Baptista A, Gola A, Huang Y, Milanez Almeida P, Torabi Parizi P, Urban J, et al. The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity. Immunity. 2019;50:1188-1201.e6 pubmed publisher
Ovadya Y, Landsberger T, Leins H, Vadai E, Gal H, Biran A, et al. Impaired immune surveillance accelerates accumulation of senescent cells and aging. Nat Commun. 2018;9:5435 pubmed publisher
Crinier A, Milpied P, Escalière B, Piperoglou C, Galluso J, Balsamo A, et al. High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice. Immunity. 2018;49:971-986.e5 pubmed publisher
Shi H, Liu C, Tan H, Li Y, Nguyen T, Dhungana Y, et al. Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity. Immunity. 2018;49:899-914.e6 pubmed publisher
O Reilly L, Putoczki T, Mielke L, Low J, Lin A, Preaudet A, et al. Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner. Immunity. 2018;48:570-583.e8 pubmed publisher
Agudo J, Park E, Rose S, Alibo E, Sweeney R, Dhainaut M, et al. Quiescent Tissue Stem Cells Evade Immune Surveillance. Immunity. 2018;48:271-285.e5 pubmed publisher
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
Roufaiel M, Gracey E, Siu A, Zhu S, Lau A, Ibrahim H, et al. CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima. Nat Immunol. 2016;17:1263-1272 pubmed publisher
Chang H, Bzeih H, Schirra C, Chitirala P, Halimani M, Cordat E, et al. Endocytosis of Cytotoxic Granules Is Essential for Multiple Killing of Target Cells by T Lymphocytes. J Immunol. 2016;197:2473-84 pubmed publisher
Chen S, Smith B, Iype J, Prestipino A, Pfeifer D, Grundmann S, et al. MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation. Blood. 2015;126:103-12 pubmed publisher
van der Sluis T, van Duikeren S, Huppelschoten S, Jordanova E, Beyranvand Nejad E, Sloots A, et al. Vaccine-induced tumor necrosis factor-producing T cells synergize with cisplatin to promote tumor cell death. Clin Cancer Res. 2015;21:781-94 pubmed publisher
Könnecke I, Serra A, El Khassawna T, Schlundt C, Schell H, Hauser A, et al. T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion. Bone. 2014;64:155-65 pubmed publisher
Hu S, Xiong N. Programmed downregulation of CCR6 is important for establishment of epidermal ??T cells by regulating their thymic egress and epidermal location. J Immunol. 2013;190:3267-75 pubmed publisher
Ardehali R, Ali S, Inlay M, Abilez O, Chen M, Blauwkamp T, et al. Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. Proc Natl Acad Sci U S A. 2013;110:3405-10 pubmed publisher
Xiao J, Angsana J, Wen J, Smith S, Park P, Ford M, et al. Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses. Arterioscler Thromb Vasc Biol. 2012;32:386-96 pubmed publisher
Morgado P, Ong Y, Boothroyd J, Lodoen M. Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun. 2011;79:4401-12 pubmed publisher
Hiraoka N, Yamazaki Itoh R, Ino Y, Mizuguchi Y, Yamada T, Hirohashi S, et al. CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in early intraepithelial stages of human pancreatic carcinogenesis. Gastroenterology. 2011;140:310-21 pubmed publisher
product information
Antigen :
CD3
Apps. Abbrev. :
Flow Cytometry, IHC-F, 3-D IHC
Cat # :
100209
Clone :
17A2
Item :
Alexa Fluor® 647 anti-mouse CD3
Isotype :
Rat IgG2b, κ
Other Names :
T cell antigen receptor complex, T3
Size :
100 μg
Price (USD) :
195 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A647
Immunogen :
γδTCR-positive T-T hybridoma D1
Application Notes :
The 17A2 antibody recognizes ε/γ (but not ε/δ) of the CD3 complex. The 17A2 antibody can induce T cell activation and has been reported to deplete CD3 + cells in vivo . Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , complement-mediated cytotoxicity 1,3 , immunohistochemical staining of acetone-fixed frozen sections 1,4 , in vitro stimulation of T cells 1 and depletion of CD3 + cells in vivo 2 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA