product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD3
catalog :
100205
quantity :
50 μg
price :
50 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
17A2
reactivity :
mouse, rat
application :
flow cytometry
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; fig 6
Xiong X, Gu L, Wang Y, Luo Y, Zhang H, Lee J, et al. Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms. J Neuroinflammation. 2016;13:241 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3
Stifter K, Schuster C, Schlosser M, Boehm B, Schirmbeck R. Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination. Sci Rep. 2016;6:29419 pubmed publisher
Zou D, Pei J, Lan J, Sang H, Chen H, Yuan H, et al. A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption. EBioMedicine. 2020;52:102652 pubmed publisher
Biram A, Winter E, Denton A, Zaretsky I, Dassa B, Bemark M, et al. B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches. Cell Rep. 2020;30:1910-1922.e5 pubmed publisher
Hidalgo San Jose L, Sunshine M, Dillingham C, Chua B, Krutá M, Hong Y, et al. Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Rep. 2020;30:69-80.e6 pubmed publisher
Kim J, Lim I, Joo H, Park C, Choi S, Jeong H, et al. Fimasartan reduces neointimal formation and inflammation after carotid arterial injury in apolipoprotein E knockout mice. Mol Med. 2019;25:33 pubmed publisher
Mariani S, Li Z, Rice S, Krieg C, Fragkogianni S, Robinson M, et al. Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells. Immunity. 2019;: pubmed publisher
Baryawno N, Przybylski D, Kowalczyk M, Kfoury Y, Severe N, Gustafsson K, et al. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia. Cell. 2019;177:1915-1932.e16 pubmed publisher
Baptista A, Gola A, Huang Y, Milanez Almeida P, Torabi Parizi P, Urban J, et al. The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity. Immunity. 2019;50:1188-1201.e6 pubmed publisher
Lin H, He C, Koprivsek J, Chen J, Zhou Z, Arulanandam B, et al. Antigen-Specific CD4+ T Cell-Derived Gamma Interferon Is Both Necessary and Sufficient for Clearing Chlamydia from the Small Intestine but Not the Large Intestine. Infect Immun. 2019;87: pubmed publisher
Doonan J, Tarafdar A, Pineda M, Lumb F, Crowe J, Khan A, et al. The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis. Nat Commun. 2019;10:1554 pubmed publisher
Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao Shen H, et al. Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms. J Clin Invest. 2019;130:1596-1611 pubmed publisher
Chan W, Entwisle C, Ercoli G, Ramos Sevillano E, McIlgorm A, Cecchini P, et al. A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge. Infect Immun. 2019;87: pubmed publisher
Delgado Benito V, Rosen D, Wang Q, Gazumyan A, Pai J, Oliveira T, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Mol Cell. 2018;72:636-649.e8 pubmed publisher
Halpern K, Shenhav R, Massalha H, Tóth B, Egozi A, Massasa E, et al. Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells. Nat Biotechnol. 2018;36:962-970 pubmed publisher
Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, et al. SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell. 2018;23:355-369.e9 pubmed publisher
Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9:2574 pubmed publisher
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science. 2018;360: pubmed publisher
Ushijima M, Uruno T, Nishikimi A, Sanematsu F, Kamikaseda Y, Kunimura K, et al. The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production. Front Immunol. 2018;9:243 pubmed publisher
Huang L, Ma Q, Li Y, Li B, Zhang L. Inhibition of microRNA-210 suppresses pro-inflammatory response and reduces acute brain injury of ischemic stroke in mice. Exp Neurol. 2018;300:41-50 pubmed publisher
Shen S, Ding W, Ahmed S, Hu R, Opalacz A, Roth S, et al. Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions. Pain Med. 2017;: pubmed publisher
Periasamy S, Porter K, Atianand M, T Le H, Earley S, Duffy E, et al. Pyrin-only protein 2 limits inflammation but improves protection against bacteria. Nat Commun. 2017;8:15564 pubmed publisher
Xu C, Ruan B, Jiang Y, Xue T, Wang Z, Lu H, et al. Antibiotics-induced gut microbiota dysbiosis promotes tumor initiation via affecting APC-Th1 development in mice. Biochem Biophys Res Commun. 2017;488:418-424 pubmed publisher
Lechner A, Driver I, Lee J, Conroy C, Nagle A, Locksley R, et al. Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy. Cell Stem Cell. 2017;21:120-134.e7 pubmed publisher
Mishra B, Lovewell R, Olive A, Zhang G, Wang W, Eugenin E, et al. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. Nat Microbiol. 2017;2:17072 pubmed publisher
Gundra U, Girgis N, Gonzalez M, San Tang M, Van Der Zande H, Lin J, et al. Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation. Nat Immunol. 2017;18:642-653 pubmed publisher
. Executive Summary of Key Concepts. HERD. 2017;10:3-5 pubmed publisher
Pedraza Zamora C, Delgado Dominguez J, Zamora Chimal J, Becker I. Th17 cells and neutrophils: Close collaborators in chronic Leishmania mexicana infections leading to disease severity. Parasite Immunol. 2017;39: pubmed publisher
Yamamura K, Uruno T, Shiraishi A, Tanaka Y, Ushijima M, Nakahara T, et al. The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. Nat Commun. 2017;8:13946 pubmed publisher
Vannini N, Girotra M, Naveiras O, Nikitin G, Campos V, Giger S, et al. Specification of haematopoietic stem cell fate via modulation of mitochondrial activity. Nat Commun. 2016;7:13125 pubmed publisher
Schmidt D, Peterlik D, Reber S, Lechner A, Männel D. Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. PLoS ONE. 2016;11:e0159059 pubmed publisher
Reboldi A, Arnon T, Rodda L, Atakilit A, Sheppard D, Cyster J. IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches. Science. 2016;352:aaf4822 pubmed publisher
Zuchtriegel G, Uhl B, Puhr Westerheide D, Pörnbacher M, Lauber K, Krombach F, et al. Platelets Guide Leukocytes to Their Sites of Extravasation. PLoS Biol. 2016;14:e1002459 pubmed publisher
Yu H, Sui Y, Wang Y, Sato N, Frey B, Xia Z, et al. Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes. PLoS ONE. 2015;10:e0143001 pubmed publisher
Stutchfield B, Antoine D, Mackinnon A, Gow D, Bain C, Hawley C, et al. CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure. Gastroenterology. 2015;149:1896-1909.e14 pubmed publisher
Chen Y, Chang S, Chen T, Lee C. Efficient Generation of Plasmacytoid Dendritic Cell from Common Lymphoid Progenitors by Flt3 Ligand. PLoS ONE. 2015;10:e0135217 pubmed publisher
Rozanski C, Utley A, Carlson L, Farren M, Murray M, Russell L, et al. CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif. J Immunol. 2015;194:4717-28 pubmed publisher
Schneider A, Kárpáti E, Schuszter K, Tóth E, Kiss E, Kulcsár M, et al. A dynamic network of estrogen receptors in murine lymphocytes: fine-tuning the immune response. J Leukoc Biol. 2014;96:857-72 pubmed publisher
Gazit R, Mandal P, Ebina W, Ben Zvi A, Nombela Arrieta C, Silberstein L, et al. Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J Exp Med. 2014;211:1315-31 pubmed publisher
Hsieh Y, Fu C, Hsieh M. Helminth-induced interleukin-4 abrogates invariant natural killer T cell activation-associated clearance of bacterial infection. Infect Immun. 2014;82:2087-97 pubmed publisher
Bedi B, Li J, Tawfeek H, Baek K, Adams J, Vangara S, et al. Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH. Proc Natl Acad Sci U S A. 2012;109:E725-33 pubmed publisher
Xiao J, Angsana J, Wen J, Smith S, Park P, Ford M, et al. Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses. Arterioscler Thromb Vasc Biol. 2012;32:386-96 pubmed publisher
Morgado P, Ong Y, Boothroyd J, Lodoen M. Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun. 2011;79:4401-12 pubmed publisher
Fathman J, Gurish M, Hemmers S, Bonham K, Friend D, Grusby M, et al. NIP45 controls the magnitude of the type 2 T helper cell response. Proc Natl Acad Sci U S A. 2010;107:3663-8 pubmed publisher
product information
Antigen :
CD3
Apps. Abbrev. :
Flow Cytometry
Cat # :
100205
Clone :
17A2
Item :
PE anti-mouse CD3
Isotype :
Rat IgG2b, κ
Other Names :
T cell antigen receptor complex, T3
Size :
50 μg
Price (USD) :
50 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
γδTCR-positive T-T hybridoma D1
Application Notes :
The 17A2 antibody recognizes ε/γ (but not ε/δ) of the CD3 complex. The 17A2 antibody can induce T cell activation and has been reported to deplete CD3 + cells in vivo . Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , complement-mediated cytotoxicity 1,3 , immunohistochemical staining of acetone-fixed frozen sections 1,4 , in vitro stimulation of T cells 1 and depletion of CD3 + cells in vivo 2 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA