Arinrad S, Wilke J, Seelbach A, Doeren J, Hindermann M, Butt U, et al. NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance. Mol Psychiatry. 2021;: pubmed publisher

Liu Y, Du J, Liu X, Wang L, Han Y, Huang C, et al. MG149 inhibits histone acetyltransferase KAT8-mediated IL-33 acetylation to alleviate allergic airway inflammation and airway hyperresponsiveness. Signal Transduct Target Ther. 2021;6:321 pubmed publisher

Neumann S, Campbell K, Woodall M, Evans M, Clarkson A, Young S. Obesity Has a Systemic Effect on Immune Cells in Naïve and Cancer-Bearing Mice. Int J Mol Sci. 2021;22: pubmed publisher

Cortés A, Solas M, Pejenaute A, Abellanas M, Garcia Lacarte M, Aymerich M, et al. Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice. Antioxidants (Basel). 2021;10: pubmed publisher

Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed publisher

Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, et al. Receptor-mediated mitophagy regulates EPO production and protects against renal anemia. elife. 2021;10: pubmed publisher

Piñeiro Hermida S, Martinez P, Blasco M. Short and dysfunctional telomeres protect from allergen-induced airway inflammation. Aging Cell. 2021;20:e13352 pubmed publisher

Nian Y, Iske J, Maenosono R, Minami K, Heinbokel T, Quante M, et al. Targeting age-specific changes in CD4+ T cell metabolism ameliorates alloimmune responses and prolongs graft survival. Aging Cell. 2021;20:e13299 pubmed publisher

Karhadkar T, Pilling D, Gomer R. Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice. PLoS ONE. 2021;16:e0245924 pubmed publisher

Zhao L, Hu S, Davila M, Yang J, Lin Y, Albanese J, et al. Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation. Mucosal Immunol. 2021;14:420-430 pubmed publisher

Cao W, Fang F, Gould T, Li X, Kim C, Gustafson C, et al. Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. J Clin Invest. 2020;130:3422-3436 pubmed publisher

Rasoulouniriana D, Santana Magal N, Gutwillig A, Farhat Younis L, Wine Y, Saperia C, et al. A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity. J Clin Invest. 2019;129:4151-4164 pubmed publisher

Wirsching H, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino P, et al. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019;4: pubmed publisher

Bottermann M, Foss S, Caddy S, Clift D, van Tienen L, Vaysburd M, et al. Complement C4 Prevents Viral Infection through Capsid Inactivation. Cell Host Microbe. 2019;25:617-629.e7 pubmed publisher

Ushiki T, Huntington N, Glaser S, Kiu H, Georgiou A, Zhang J, et al. Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells. PLoS ONE. 2016;11:e0162111 pubmed publisher

Kong S, Yang Y, Xu Y, Wang Y, Zhang Y, Melo Cardenas J, et al. Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas. Proc Natl Acad Sci U S A. 2016;113:10394-9 pubmed publisher

Pietras E, Mirantes Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol. 2016;18:607-18 pubmed publisher

Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed publisher

Marek I, Lichtneger T, Cordasic N, Hilgers K, Volkert G, Fahlbusch F, et al. Alpha8 Integrin (Itga8) Signalling Attenuates Chronic Renal Interstitial Fibrosis by Reducing Fibroblast Activation, Not by Interfering with Regulation of Cell Turnover. PLoS ONE. 2016;11:e0150471 pubmed publisher

Haque M, Song J, Fino K, Sandhu P, Song X, Lei F, et al. Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity. Sci Rep. 2016;6:20588 pubmed publisher

Kuipers H, Rieck M, Gurevich I, Nagy N, Butte M, Negrin R, et al. Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization. Proc Natl Acad Sci U S A. 2016;113:1339-44 pubmed publisher

Lasigliè D, Boero S, Bauer I, Morando S, Damonte P, Cea M, et al. Sirt6 regulates dendritic cell differentiation, maturation, and function. Aging (Albany NY). 2016;8:34-49 pubmed

von Moltke J, Ji M, Liang H, Locksley R. Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit. Nature. 2016;529:221-5 pubmed publisher

Kim J, Phan T, Nguyen V, Dinh Vu H, Zheng J, Yun M, et al. Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β. Theranostics. 2015;5:1328-42 pubmed publisher

Smith K, Filbey K, Reynolds L, Hewitson J, Harcus Y, Boon L, et al. Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths. Mucosal Immunol. 2016;9:428-43 pubmed publisher

Dahlgren M, Gustafsson Hedberg T, Livingston M, Cucak H, Alsén S, Yrlid U, et al. T follicular helper, but not Th1, cell differentiation in the absence of conventional dendritic cells. J Immunol. 2015;194:5187-99 pubmed publisher

Kanayama M, Inoue M, Danzaki K, Hammer G, He Y, Shinohara M. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nat Commun. 2015;6:5779 pubmed publisher

Al Barwani F, Young S, Baird M, Larsen D, Ward V. Mannosylation of virus-like particles enhances internalization by antigen presenting cells. PLoS ONE. 2014;9:e104523 pubmed publisher

Johannesson B, Sattler S, Semenova E, Pastore S, Kennedy Lydon T, Sampson R, et al. Insulin-like growth factor-1 induces regulatory T cell-mediated suppression of allergic contact dermatitis in mice. Dis Model Mech. 2014;7:977-85 pubmed publisher

Kang Y, Paik H, Zhang S, Chen J, Olson O, Mitchell C, et al. Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production. J Exp Med. 2023;220: pubmed publisher

Mammadli M, Suo L, Sen J, Karimi M. TCF-1 Is Required for CD4 T Cell Persistence Functions during AlloImmunity. Int J Mol Sci. 2023;24: pubmed publisher

Glaubitz J, Wilden A, Frost F, Ameling S, Homuth G, Mazloum H, et al. Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis. Gut. 2023;72:1355-1369 pubmed publisher

Zhao J, Jung S, Li X, Li L, Kasinath V, Zhang H, et al. Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice. J Clin Invest. 2022;132: pubmed publisher

Moore A, Vivanco Gonzalez N, Plummer K, Mitchel O, Kaur H, Rivera M, et al. Gestationally dependent immune organization at the maternal-fetal interface. Cell Rep. 2022;41:111651 pubmed publisher

Russo E, Lema xee tre F, Corre B, Chikina A, Langa Vives F, Bousso P. SPICE-Met: profiling and imaging energy metabolism at the single-cell level using a fluorescent reporter mouse. EMBO J. 2022;41:e111528 pubmed publisher

Glaubitz J, Wilden A, Golchert J, Homuth G, V xf6 lker U, Br xf6 ker B, et al. In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response. Nat Commun. 2022;13:4502 pubmed publisher

Robles Valero J, Fern xe1 ndez Nevado L, Cuadrado M, Lorenzo Mart xed n L, Fern xe1 ndez Pisonero I, Abad A, et al. Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model. Mol Oncol. 2022;16:3533-3553 pubmed publisher

Flietner E, Wen Z, Rajagopalan A, Jung O, Watkins L, Wiesner J, et al. Ponatinib sensitizes myeloma cells to MEK inhibition in the high-risk VQ model. Sci Rep. 2022;12:10616 pubmed publisher

Campisi L, Chizari S, Ho J, Gromova A, Arnold F, Mosca L, et al. Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4. Nature. 2022;606:945-952 pubmed publisher

Liu J, Liang X, Li M, Lin F, Ma X, Xin Y, et al. Intramyocardial injected human umbilical cord-derived mesenchymal stem cells (HucMSCs) contribute to the recovery of cardiac function and the migration of CD4+ T cells into the infarcted heart via CCL5/CCR5 signaling. Stem Cell Res Ther. 2022;13:247 pubmed publisher

Potempa M, Aguilar O, Gonzalez Hinojosa M, Tenvooren I, Marquez D, Spitzer M, et al. Influence of Self-MHC Class I Recognition on the Dynamics of NK Cell Responses to Cytomegalovirus Infection. J Immunol. 2022;208:1742-1754 pubmed publisher

Valet C, Magnen M, Qiu L, Cleary S, Wang K, Ranucci S, et al. Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression. J Clin Invest. 2022;132: pubmed publisher

Fueyo Gonz xe1 lez F, McGinty M, Ningoo M, Anderson L, Cantarelli C, Andrea Angeletti -, et al. Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation. Immunity. 2022;55:459-474.e7 pubmed publisher

Cautivo K, Matatia P, Lizama C, Mroz N, Dahlgren M, Yu X, et al. Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation. Immunity. 2022;55:254-271.e7 pubmed publisher

Rastelli D, Robinson A, Lagomarsino V, Matthews L, Hassan R, Perez K, et al. Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice. J Clin Invest. 2022;132: pubmed publisher

You X, Yang Q, Yan K, Wang S, Huang R, WANG S, et al. Multi-Omics Profiling Identifies Pathways Associated With CD8+ T-Cell Activation in Severe Aplastic Anemia. Front Genet. 2021;12:790990 pubmed publisher

Moretti F, Giardino G, Attenborough T, Gkazi A, Margetts B, la Marca G, et al. Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy. Sci Rep. 2021;11:23221 pubmed publisher

Boothby I, Kinet M, Boda D, Kwan E, Clancy S, Cohen J, et al. Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. Nature. 2021;599:667-672 pubmed publisher

Lu X, Hosono Y, Nagae M, Ishizuka S, Ishikawa E, Motooka D, et al. Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients. J Exp Med. 2021;218: pubmed publisher

Robles Valero J, Fernandez Nevado L, Lorenzo Martín L, Cuadrado M, Fernández Pisonero I, Rodríguez Fdez S, et al. Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. EMBO J. 2021;40:e108125 pubmed publisher

Jiang P, Zhang Y, Ru B, Yang Y, Vu T, Paul R, et al. Systematic investigation of cytokine signaling activity at the tissue and single-cell levels. Nat Methods. 2021;18:1181-1191 pubmed publisher

Pack A, Schwartzhoff P, Zacharias Z, Fernández Ruiz D, Heath W, Gurung P, et al. Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity. Cell Rep. 2021;36:109586 pubmed publisher

Li T, Jiang J, Qie C, Xuan C, Hu X, Liu W, et al. Identification of active small-molecule modulators targeting the novel immune checkpoint VISTA. BMC Immunol. 2021;22:55 pubmed publisher

Zhao J, Jiang L, Uehara M, Banouni N, Al Dulaijan B, Azzi J, et al. ACTH treatment promotes murine cardiac allograft acceptance. JCI Insight. 2021;6: pubmed publisher

He Y, Yang Z, Zhao C, Xiao Z, Gong Y, Li Y, et al. T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1. elife. 2021;10: pubmed publisher

Wabitsch S, McCallen J, Ma C, Greten T. Evaluating the impact of hydroxychloroquine on mouse lymphocyte proliferation and cytokine production in vivo and in vitro. STAR Protoc. 2021;2:100517 pubmed publisher

Heib T, Hermanns H, Manukjan G, Englert M, Kusch C, Becker I, et al. RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes. Cell Rep. 2021;35:109102 pubmed publisher

Zhang Z, Huang X, Wang E, Huang Y, Yang R. Identification and characterization of B220+/B220- subpopulations in murine Gr1+CD11b+ cells during tumorigenesis. Oncoimmunology. 2021;10:1912472 pubmed publisher

Haque M, Lei F, Xiong X, Ren Y, Peng H, Wang L, et al. Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HIV Replication and PD-1 Expression on CD4+ T Cells. Viruses. 2021;13: pubmed publisher

Go D, Lee S, Lee S, Woo S, Kim K, Kim K, et al. Programmed Death Ligand 1-Expressing Classical Dendritic Cells MitigateHelicobacter-Induced Gastritis. Cell Mol Gastroenterol Hepatol. 2021;12:715-739 pubmed publisher

Garo L, Ajay A, Fujiwara M, Gabriely G, Raheja R, Kuhn C, et al. MicroRNA-146a limits tumorigenic inflammation in colorectal cancer. Nat Commun. 2021;12:2419 pubmed publisher

Pan S, Tan H, Chang R, Wang Q, Zhu Y, Chen L, et al. High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms. Front Cell Dev Biol. 2021;9:629306 pubmed publisher

He L, Valignat M, Zhang L, Gelard L, Zhang F, Le Guen V, et al. ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding. EMBO Rep. 2021;22:e52196 pubmed publisher

Mayer K, Smole U, Zhu C, Derdak S, Minervina A, Salnikova M, et al. The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells. FASEB J. 2021;35:e21217 pubmed publisher

Gern B, Adams K, Plumlee C, Stoltzfus C, Shehata L, Moguche A, et al. TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma. Cell Host Microbe. 2021;29:594-606.e6 pubmed publisher

Mao F, Lv Y, Hao C, Teng Y, Liu Y, Cheng P, et al. Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense. Cell Mol Gastroenterol Hepatol. 2021;12:395-425 pubmed publisher

Mohrin M, Liu J, Zavala Solorio J, Bhargava S, Maxwell Trumble J, Brito A, et al. Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells. Aging Cell. 2021;20:e13313 pubmed publisher

Dooley K, McConnell R, Xu K, Lewis N, Haupt S, Youniss M, et al. A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties. Mol Ther. 2021;29:1729-1743 pubmed publisher

Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher

K xe4 stele V, Mayer J, Lee E, Papazian N, Cole J, Cerovic V, et al. Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection. Mucosal Immunol. 2021;14:717-727 pubmed publisher

Link C, Rau C, Udoye C, Ragab M, Korkmaz R, Comd xfc hr S, et al. IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice. Front Immunol. 2020;11:596772 pubmed publisher

Song M, YEKU O, Rafiq S, Purdon T, Dong X, Zhu L, et al. Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Nat Commun. 2020;11:6298 pubmed publisher

Unsinger J, Walton A, Blood T, Tenney D, Quigley M, Drewry A, et al. Frontline Science: OX40 agonistic antibody reverses immune suppression and improves survival in sepsis. J Leukoc Biol. 2021;109:697-708 pubmed publisher

Srey M, Taccogna A, Oksov Y, Lustigman S, Tai P, Acord J, et al. Vaccination with novel low-molecular weight proteins secreted from Trichinella spiralis inhibits establishment of infection. PLoS Negl Trop Dis. 2020;14:e0008842 pubmed publisher

Fernandez Orth J, Rolfes L, Gola L, Bittner S, Andronic J, Sukhorukov V, et al. A role for TASK2 channels in the human immunological synapse. Eur J Immunol. 2021;51:342-353 pubmed publisher

Plumlee C, Duffy F, Gern B, Delahaye J, Cohen S, Stoltzfus C, et al. Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis. Cell Host Microbe. 2021;29:68-82.e5 pubmed publisher

Chen L, Zheng H, Yu X, Liu L, Li H, Zhu H, et al. Tumor-Secreted GRP78 Promotes the Establishment of a Pre-metastatic Niche in the Liver Microenvironment. Front Immunol. 2020;11:584458 pubmed publisher

Boyd D, Allen E, Randolph A, Guo X, Weng Y, Sanders C, et al. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020;587:466-471 pubmed publisher

Karhadkar T, Pilling D, Gomer R. Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice. bioRxiv. 2020;: pubmed publisher

Zelco A, Rocha Ferreira E, Nazmi A, Ardalan M, Chumak T, Nilsson G, et al. Type 2 Innate Lymphoid Cells Accumulate in the Brain After Hypoxia-Ischemia but Do Not Contribute to the Development of Preterm Brain Injury. Front Cell Neurosci. 2020;14:249 pubmed publisher

Forsyth K, Roy N, Peauroi E, Dehaven B, Wold E, Hersperger A, et al. Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+ T cells post peptide loading. PLoS Pathog. 2020;16:e1008685 pubmed publisher

Lim C, Porter D, Orandle M, Green B, Barnes M, Croston T, et al. Resolution of Pulmonary Inflammation Induced by Carbon Nanotubes and Fullerenes in Mice: Role of Macrophage Polarization. Front Immunol. 2020;11:1186 pubmed publisher

Yoshihara T, Oikawa Y, Kato T, Kessoku T, Kobayashi T, Kato S, et al. The protective effect of Bifidobacterium bifidum G9-1 against mucus degradation by Akkermansia muciniphila following small intestine injury caused by a proton pump inhibitor and aspirin. Gut Microbes. 2020;11:1385-1404 pubmed publisher

Liu T, Yang L, Han X, Ding X, Li J, Yang J. Local sympathetic innervations modulate the lung innate immune responses. Sci Adv. 2020;6:eaay1497 pubmed publisher

Bittner Eddy P, Fischer L, Costalonga M. Transient Expression of IL-17A in Foxp3 Fate-Tracked Cells in Porphyromonas gingivalis-Mediated Oral Dysbiosis. Front Immunol. 2020;11:677 pubmed publisher

Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed publisher

Zhang Z, Huang X, Wang E, Huang Y, Yang R. Suppression of Mll1-Complex by Stat3/Cebpβ-Induced miR-21a/21b/181b Maintains the Accumulation, Homeostasis, and Immunosuppressive Function of Polymorphonuclear Myeloid-Derived Suppressor Cells. J Immunol. 2020;204:3400-3415 pubmed publisher

Schuler C, Malinczak C, Best S, Morris S, Rasky A, Ptaschinski C, et al. Inhibition of uric acid or IL-1β ameliorates respiratory syncytial virus immunopathology and development of asthma. Allergy. 2020;75:2279-2293 pubmed publisher

Gaspar M, Pravin J, Rodrigues L, Uhlenbroich S, Everett K, Wollerton F, et al. CD137/OX40 Bispecific Antibody Induces Potent Antitumor Activity that Is Dependent on Target Coengagement. Cancer Immunol Res. 2020;8:781-793 pubmed publisher

Kang L, Oh E, Cho C, Kwon H, Lee C, Jeon J, et al. 3'-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models. Sci Rep. 2020;10:5603 pubmed publisher

von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed publisher

Doll J, Hoebe K, Thompson R, Sawtell N. Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction. PLoS Pathog. 2020;16:e1008296 pubmed publisher

Liu C, Schaettler M, Blaha D, Bowman Kirigin J, Kobayashi D, Livingstone A, et al. Treatment of an aggressive orthotopic murine glioblastoma model with combination checkpoint blockade and a multivalent neoantigen vaccine. Neuro Oncol. 2020;22:1276-1288 pubmed publisher

Bernstein D, Gajghate S, Reichenbach N, Winfield M, Persidsky Y, Heldt N, et al. let-7g counteracts endothelial dysfunction and ameliorating neurological functions in mouse ischemia/reperfusion stroke model. Brain Behav Immun. 2020;87:543-555 pubmed publisher

Yan J, Li X, Roman Aguilera A, Xiao C, Jacoberger Foissac C, Nowlan B, et al. Control of Metastases via Myeloid CD39 and NK Cell Effector Function. Cancer Immunol Res. 2020;8:356-367 pubmed publisher

Schafflick D, Xu C, Hartlehnert M, Cole M, Schulte Mecklenbeck A, Lautwein T, et al. Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis. Nat Commun. 2020;11:247 pubmed publisher

Gilfillan C, Wang C, Mohsen M, Rufer N, Hebeisen M, Allard M, et al. Murine CD8 T-cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density. Eur J Immunol. 2020;50:505-514 pubmed publisher

Clark K, Yau J, Bloom A, Wang J, Venzon D, Suzuki M, et al. Structure-Function Implications of the Ability of Monoclonal Antibodies Against α-Galactosylceramide-CD1d Complex to Recognize β-Mannosylceramide Presentation by CD1d. Front Immunol. 2019;10:2355 pubmed publisher

Hawse W, Cattley R, Wendell S. Cutting Edge: TCR Signal Strength Regulates Acetyl-CoA Metabolism via AKT. J Immunol. 2019;203:2771-2775 pubmed publisher

Levy B, Abdulnour R, Tavares A, Bruggemann T, Norris P, Bai Y, et al. Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. J Allergy Clin Immunol. 2020;145:335-344 pubmed publisher

Karhadkar T, Chen W, Gomer R. Attenuated pulmonary fibrosis in sialidase-3 knockout (Neu3-/-) mice. Am J Physiol Lung Cell Mol Physiol. 2020;318:L165-L179 pubmed publisher

Katsuyama T, Li H, Comte D, Tsokos G, Moulton V. Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity. J Clin Invest. 2019;129:5411-5423 pubmed publisher

Kulkarni N, Takahashi T, Sanford J, Tong Y, Gombart A, Hinds B, et al. Innate Immune Dysfunction in Rosacea Promotes Photosensitivity and Vascular Adhesion Molecule Expression. J Invest Dermatol. 2020;140:645-655.e6 pubmed publisher

Egaña Gorroño L, Chinnasamy P, Casimiro I, Almonte V, Parikh D, Oliveira Paula G, et al. Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019;289:184-194 pubmed publisher

Chen X, Lei F, Wang L, Xiong X, Song J. In Vitro Differentiation of T Cells from Murine Pluripotent Stem Cells. Methods Mol Biol. 2019;2048:131-141 pubmed publisher

Zhang J, Pang Y, Xie T, Zhu L. CXCR4 antagonism in combination with IDO1 inhibition weakens immune suppression and inhibits tumor growth in mouse breast cancer bone metastases. Onco Targets Ther. 2019;12:4985-4992 pubmed publisher

Thulasingam S, Krishnasamy S, Raj C D, Lasch M, Vedantham S, Deindl E. Insulin Treatment Forces Arteriogenesis in Diabetes Mellitus by Upregulation of the Early Growth Response-1 (Egr-1) Pathway in Mice. Int J Mol Sci. 2019;20: pubmed publisher

Abdel Gadir A, Stephen Victor E, Gerber G, Noval Rivas M, Wang S, Harb H, et al. Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy. Nat Med. 2019;: pubmed publisher

Yamashita M, Passegue E. TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell. 2019;: pubmed publisher

Davies C, Patir A, McColl B. Myeloid Cell and Transcriptome Signatures Associated With Inflammation Resolution in a Model of Self-Limiting Acute Brain Inflammation. Front Immunol. 2019;10:1048 pubmed publisher

Moon H, Zhu J, Donahue L, Choi E, White A. Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress. Nat Commun. 2019;10:2225 pubmed publisher

Kerdidani D, Chouvardas P, Arjo A, Giopanou I, Ntaliarda G, Guo Y, et al. Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma. Nat Commun. 2019;10:1405 pubmed publisher

Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, et al. Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115. Virulence. 2019;10:248-259 pubmed publisher

Miret J, Kirschmeier P, Koyama S, Zhu M, Li Y, Naito Y, et al. Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity. J Immunother Cancer. 2019;7:32 pubmed publisher

Di Dalmazi G, Chalan P, Caturegli P. MYMD-1, a Novel Immunometabolic Regulator, Ameliorates Autoimmune Thyroiditis via Suppression of Th1 Responses and TNF-α Release. J Immunol. 2019;202:1350-1362 pubmed publisher

Patterson A, Bolcas P, Lampe K, Cantrell R, Ruff B, Lewkowich I, et al. Loss of GTPase of immunity-associated protein 5 (Gimap5) promotes pathogenic CD4+ T-cell development and allergic airway disease. J Allergy Clin Immunol. 2019;143:245-257.e6 pubmed publisher

Düsedau H, Kleveman J, Figueiredo C, Biswas A, Steffen J, Kliche S, et al. p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation. Glia. 2019;67:193-211 pubmed publisher

Kim C, Lee C, Jung J, Ghosh A, Hasan S, Hwang S, et al. The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus. Immunity. 2018;49:1034-1048.e8 pubmed publisher

Recino A, Gan S, Sia K, Sawyer Y, Trendell J, Kay R, et al. Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice. Gene Ther. 2019;26:40-56 pubmed publisher

Wang W, Marinis J, Beal A, Savadkar S, Wu Y, Khan M, et al. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer. Cancer Cell. 2018;34:757-774.e7 pubmed publisher

Fatkhullina A, Peshkova I, Dzutsev A, Aghayev T, McCulloch J, Thovarai V, et al. An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis. Immunity. 2018;49:943-957.e9 pubmed publisher

Bartolacci C, Andreani C, Curcio C, Occhipinti S, Massaccesi L, Giovarelli M, et al. Phage-Based Anti-HER2 Vaccination Can Circumvent Immune Tolerance against Breast Cancer. Cancer Immunol Res. 2018;6:1486-1498 pubmed publisher

Williams S, Fairless R, Maier O, Liermann P, Pichi K, Fischer R, et al. Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis. Sci Rep. 2018;8:13628 pubmed publisher

Englezou P, Sapet C, Démoulins T, Milona P, Ebensen T, Schulze K, et al. Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids. Mol Ther Nucleic Acids. 2018;12:118-134 pubmed publisher

Liu M, Peng J, Tai N, Pearson J, Hu C, Guo J, et al. Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes. Diabetologia. 2018;61:2333-2343 pubmed publisher

Diao J, Gu H, Tang M, Zhao J, Cattral M. Tumor Dendritic Cells (DCs) Derived from Precursors of Conventional DCs Are Dispensable for Intratumor CTL Responses. J Immunol. 2018;201:1306-1314 pubmed publisher

Child K, Herrick D, Schwob J, Holbrook E, Jang W. The Neuroregenerative Capacity of Olfactory Stem Cells Is Not Limitless: Implications for Aging. J Neurosci. 2018;38:6806-6824 pubmed publisher

Mainini F, Larsen D, Webster G, Young S, Eccles M. MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells. Nucleic Acid Ther. 2018;28:225-232 pubmed publisher

Adamson S, Polanowska Grabowska R, Marqueen K, Griffiths R, Angdisen J, Breevoort S, et al. Deficiency of Dab2 (Disabled Homolog 2) in Myeloid Cells Exacerbates Inflammation in Liver and Atherosclerotic Plaques in LDLR (Low-Density Lipoprotein Receptor)-Null Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2018;38:1020-1029 pubmed publisher

Shin J, Fukuhara A, Onodera T, Kita S, Yokoyama C, Otsuki M, et al. SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes. Diabetes. 2018;67:1068-1078 pubmed publisher

Pushalkar S, Hundeyin M, Daley D, Zambirinis C, Kurz E, Mishra A, et al. The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression. Cancer Discov. 2018;8:403-416 pubmed publisher

Burrello C, Garavaglia F, Cribiù F, Ercoli G, Bosari S, Caprioli F, et al. Short-term Oral Antibiotics Treatment Promotes Inflammatory Activation of Colonic Invariant Natural Killer T and Conventional CD4+ T Cells. Front Med (Lausanne). 2018;5:21 pubmed publisher

Lee Y, Lee J, Jang Y, Seo S, Chang J, Seong B. Non-specific Effect of Vaccines: Immediate Protection against Respiratory Syncytial Virus Infection by a Live Attenuated Influenza Vaccine. Front Microbiol. 2018;9:83 pubmed publisher

Mazor R, King E, Onda M, Cuburu N, Addissie S, Crown D, et al. Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity. Proc Natl Acad Sci U S A. 2018;115:E733-E742 pubmed publisher

Chen Y, Li Q, Li X, Ma D, Fang J, Luo L, et al. Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa. Oncoimmunology. 2018;7:e1388484 pubmed publisher

Regan Komito D, Valaris S, Kapellos T, Recio C, Taylor L, Greaves D, et al. Absence of the Non-Signalling Chemerin Receptor CCRL2 Exacerbates Acute Inflammatory Responses In Vivo. Front Immunol. 2017;8:1621 pubmed publisher

Hayashi Y, Kawakubo Yasukochi T, Mizokami A, Hazekawa M, Yakura T, Naito M, et al. Uncarboxylated Osteocalcin Induces Antitumor Immunity against Mouse Melanoma Cell Growth. J Cancer. 2017;8:2478-2486 pubmed publisher

Kawabe T, Jankovic D, Kawabe S, Huang Y, Lee P, Yamane H, et al. Memory-phenotype CD4+ T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function. Sci Immunol. 2017;2: pubmed publisher

Sugita S, Shimizu J, Makabe K, Keino H, Watanabe T, Takahashi M. Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody. Arthritis Res Ther. 2017;19:176 pubmed publisher

Xu L, Zhang W, Zeng L, Jin J. Rehmannia glutinosa polysaccharide induced an anti-cancer effect by activating natural killer cells. Int J Biol Macromol. 2017;105:680-685 pubmed publisher

Akiel M, Guo C, Li X, Rajasekaran D, Mendoza R, Robertson C, et al. IGFBP7 Deletion Promotes Hepatocellular Carcinoma. Cancer Res. 2017;77:4014-4025 pubmed publisher

Shao Y, Zhu W, Da J, Xu M, Wang Y, Zhou J, et al. Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancer. Onco Targets Ther. 2017;10:2675-2683 pubmed publisher

Shimokawa C, Kanaya T, Hachisuka M, Ishiwata K, Hisaeda H, Kurashima Y, et al. Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections. Immunity. 2017;46:863-874.e4 pubmed publisher

Zareie P, Connor B, La Flamme A. Amelioration of experimental autoimmune encephalomyelitis by clozapine is not associated with defective CD4 T cell responses. J Neuroinflammation. 2017;14:68 pubmed publisher

Fitzpatrick E, You D, Shrestha B, Siefker D, Patel V, Yadav N, et al. A Neonatal Murine Model of MRSA Pneumonia. PLoS ONE. 2017;12:e0169273 pubmed publisher

He X, Lin H, Yuan L, Li B. Combination therapy with L-arginine and α-PD-L1 antibody boosts immune response against osteosarcoma in immunocompetent mice. Cancer Biol Ther. 2017;18:94-100 pubmed publisher

Gonzales C, Yoshihara H, Dilek N, Leignadier J, Irving M, Miéville P, et al. In-Vivo Detection and Tracking of T Cells in Various Organs in a Melanoma Tumor Model by 19F-Fluorine MRS/MRI. PLoS ONE. 2016;11:e0164557 pubmed publisher

Kopec A, Sullivan B, Kassel K, Joshi N, Luyendyk J. Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in mice. Toxicol Sci. 2014;141:515-23 pubmed publisher

Könnecke I, Serra A, El Khassawna T, Schlundt C, Schell H, Hauser A, et al. T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion. Bone. 2014;64:155-65 pubmed publisher

Lei F, Haque R, Xiong X, Song J. Directed differentiation of induced pluripotent stem cells towards T lymphocytes. J Vis Exp. 2012;:e3986 pubmed publisher

Xiao J, Angsana J, Wen J, Smith S, Park P, Ford M, et al. Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses. Arterioscler Thromb Vasc Biol. 2012;32:386-96 pubmed publisher

Morgado P, Ong Y, Boothroyd J, Lodoen M. Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun. 2011;79:4401-12 pubmed publisher

Yadav A, Vallabu S, Kumar D, Ding G, Charney D, Chander P, et al. HIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation. Am J Physiol Renal Physiol. 2010;298:F734-44 pubmed publisher

Hamada T, Tsuchihashi S, Avanesyan A, Duarte S, Moore C, Busuttil R, et al. Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury. J Immunol. 2008;180:1843-53 pubmed

Bergstrom K, Guttman J, Rumi M, Ma C, Bouzari S, Khan M, et al. Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen. Infect Immun. 2008;76:796-811 pubmed

Tilley S, Jaradat M, Stapleton C, Dixon D, Hua X, Erikson C, et al. Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen. J Immunol. 2007;178:3208-18 pubmed