product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoPlus anti-mouse 4-1BB (CD137)
catalog :
BP0239-5MG
quantity :
5 mg
price :
1,700.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
9H10-CP146
reactivity :
mouse
more info or order :
citations: 7
Reference
Qi X, Li F, Wu Y, Cheng C, Han P, Wang J, et al. Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity. Nat Commun. 2019;10:2141 pubmed publisher
Giardino Torchia M, Munitic I, Castro E, Herz J, McGavern D, Ashwell J. c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival. Eur J Immunol. 2015;45:2672-82 pubmed publisher
Kobayashi T, Doff B, Rearden R, Leggatt G, Mattarollo S. NKT cell-targeted vaccination plus anti-4-1BB antibody generates persistent CD8 T cell immunity against B cell lymphoma. Oncoimmunology. 2015;4:e990793 pubmed
Guillerey C, Ferrari de Andrade L, Vuckovic S, Miles K, Ngiow S, Yong M, et al. Immunosurveillance and therapy of multiple myeloma are CD226 dependent. J Clin Invest. 2015;125:2077-89 pubmed publisher
Tewalt E, Cohen J, Rouhani S, Guidi C, Qiao H, Fahl S, et al. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood. 2012;120:4772-82 pubmed publisher
Verbrugge I, Hagekyriakou J, Sharp L, Galli M, West A, McLaughlin N, et al. Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies. Cancer Res. 2012;72:3163-74 pubmed publisher
Vezys V, Penaloza MacMaster P, Barber D, Ha S, Konieczny B, Freeman G, et al. 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. J Immunol. 2011;187:1634-42 pubmed publisher
product information
Catalog Number :
BP0239-5MG
Product Name :
InVivoPlus anti-mouse 4-1BB (CD137)
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
5 mg
Regular Price :
$2,615.00
Academic Price :
1,700.00 USD
Clone Name :
9H10-CP146
Isotype :
3H3
Immunogen :
Mouse CD137 human Fc fusion protein
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo 4-1BB stimulation, in vitro 4-1BB stimulation
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA