| Published Application/Species/Sample/Dilution | Reference |
|---|
- blocking or activating experiments; mouse; fig 5b
| Zhang G, Li M, Zhou D, Yang X, Zhang W, Gao R. Loss of endothelial EMCN drives tumor lung metastasis through the premetastatic niche. J Transl Med. 2022;20:446 pubmed publisher |
- blocking or activating experiments; mouse; fig 4d
| Fischer A, Wannemacher J, Christ S, Koopmans T, Kadri S, Zhao J, et al. Neutrophils direct preexisting matrix to initiate repair in damaged tissues. Nat Immunol. 2022;23:518-531 pubmed publisher |
- blocking or activating experiments; mouse; fig s6a
| Wutschka J, Kast B, Sator Schmitt M, Appak Baskoy S, Hess J, Sinn H, et al. JUNB suppresses distant metastasis by influencing the initial metastatic stage. Clin Exp Metastasis. 2021;38:411-423 pubmed publisher |
- blocking or activating experiments; mouse; ; fig 2f
| Uyanik B, Goloudina A, Akbarali A, Grigorash B, Petukhov A, Singhal S, et al. Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses. Nat Commun. 2021;12:3622 pubmed publisher |
- blocking or activating experiments; mouse; fig 5d
| Uhl B, Braun C, Dominik J, Luft J, Canis M, Reichel C. A Novel Experimental Approach for In Vivo Analyses of the Salivary Gland Microvasculature. Front Immunol. 2020;11:604470 pubmed publisher |
- blocking or activating experiments; mouse; fig 1d
| Lim C, Or Y, Ong Z, Chung H, Hayashi H, Shrestha S, et al. Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism. elife. 2020;9: pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig s7a
| Bosiljcic M, Cederberg R, Hamilton M, Lepard N, Harbourne B, Collier J, et al. Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs. Breast Cancer Res. 2019;21:103 pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig 2b
| Spolski R, West E, Li P, Veenbergen S, Yung S, Kazemian M, et al. IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus. elife. 2019;8: pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 1a
| Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019;567:249-252 pubmed publisher |
- blocking or activating experiments; mouse; fig 4c
- immunohistochemistry - paraffin section; mouse; loading ...; fig 4b
- flow cytometry; mouse; loading ...; fig 4a
| Abeln M, Albers I, Peters Bernard U, Flächsig Schulz K, Kats E, Kispert A, et al. Sialic acid is a critical fetal defense against maternal complement attack. J Clin Invest. 2019;129:422-436 pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig 6b
| Kwan B, Zhu E, Tzeng A, Sugito H, Eltahir A, Ma B, et al. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. J Exp Med. 2017;214:1679-1690 pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig 7i
| Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher |
- blocking or activating experiments; mouse; loading ...
| Kishimoto Y, Asakawa S, Sato T, Takano T, Nakajyo T, Mizuno N, et al. Induced histamine regulates Ni elution from an implanted Ni wire in mice by downregulating neutrophil migration. Exp Dermatol. 2017;26:868-874 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s4c
| Hahm E, Wei C, Fernandez I, Li J, Tardi N, Tracy M, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nat Med. 2017;23:100-106 pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig 4a
| Theeß W, Sellau J, Steeg C, Klinke A, Baldus S, Cramer J, et al. Myeloperoxidase Attenuates Pathogen Clearance during Plasmodium yoelii Nonlethal Infection. Infect Immun. 2017;85: pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig s4
| Takeshima T, Pop L, Laine A, Iyengar P, Vitetta E, Hannan R. Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF. Proc Natl Acad Sci U S A. 2016;113:11300-11305 pubmed |
- blocking or activating experiments; mouse; loading ...; fig 3h
- flow cytometry; mouse; loading ...; fig 3c
| Altmeier S, Toska A, Sparber F, Teijeira A, Halin C, LeibundGut Landmann S. IL-1 Coordinates the Neutrophil Response to C. albicans in the Oral Mucosa. PLoS Pathog. 2016;12:e1005882 pubmed publisher |
- blocking or activating experiments; mouse; fig 5
| Mostafa H, Vogel P, Srinivasan A, Russell C. Non-invasive Imaging of Sendai Virus Infection in Pharmacologically Immunocompromised Mice: NK and T Cells, but not Neutrophils, Promote Viral Clearance after Therapy with Cyclophosphamide and Dexamethasone. PLoS Pathog. 2016;12:e1005875 pubmed publisher |
- blocking or activating experiments; mouse; loading ...; fig s2
| Barin J, Talor M, Schaub J, Diny N, Hou X, Hoyer M, et al. Collaborative Interferon-? and Interleukin-17 Signaling Protects the Oral Mucosa from Staphylococcus aureus. Am J Pathol. 2016;186:2337-52 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 2a
- immunohistochemistry; mouse; loading ...; fig 1d
| Woytschak J, Keller N, Krieg C, Impellizzieri D, Thompson R, Wynn T, et al. Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation. Immunity. 2016;45:172-84 pubmed publisher |
- immunoprecipitation; mouse; loading ...; fig 4
| Russell R, McDonald J, Ivanova M, Zhong Z, Bukreyev A, Tregoning J. Partial Attenuation of Respiratory Syncytial Virus with a Deletion of a Small Hydrophobic Gene Is Associated with Elevated Interleukin-1β Responses. J Virol. 2015;89:8974-81 pubmed publisher |
- blocking or activating experiments; mouse; fig 1
| Wilson C, Jurk D, Fullard N, Banks P, Page A, Luli S, et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818 pubmed publisher |
- blocking or activating experiments; mouse
| Dal Secco D, Wang J, Zeng Z, Kolaczkowska E, Wong C, Petri B, et al. A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury. J Exp Med. 2015;212:447-56 pubmed publisher |
- blocking or activating experiments; mouse
| Yamada D, Elsaesser H, Lux A, Timmerman J, Morrison S, de la Torre J, et al. Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection. Immunity. 2015;42:379-390 pubmed publisher |
- blocking or activating experiments; mouse; fig s2
| Tanaka T, Kajiwara T, Torigoe T, Okamoto Y, Sato N, Tamura Y. Cancer-associated oxidoreductase ERO1-α drives the production of tumor-promoting myeloid-derived suppressor cells via oxidative protein folding. J Immunol. 2015;194:2004-10 pubmed publisher |
| Davis R, Snyder E, Miller J, Carter S, Houser C, Klampatsa A, et al. Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy. Photochem Photobiol. 2019;95:430-438 pubmed publisher |
| Moynihan K, Opel C, Szeto G, Tzeng A, Zhu E, Engreitz J, et al. Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nat Med. 2016;22:1402-1410 pubmed publisher |
| Chorny A, Casas Recasens S, Sintes J, Shan M, Polentarutti N, García Escudero R, et al. The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells. J Exp Med. 2016;213:2167-85 pubmed publisher |
| Jorgensen I, Zhang Y, Krantz B, Miao E. Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. J Exp Med. 2016;213:2113-28 pubmed publisher |
| Henry E, Sy C, Inclan Rico J, Espinosa V, Ghanny S, Dwyer D, et al. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016;213:1663-73 pubmed publisher |
| Parsa R, Lund H, Georgoudaki A, Zhang X, Ortlieb Guerreiro Cacais A, Grommisch D, et al. BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis. J Exp Med. 2016;213:1537-53 pubmed publisher |
| Ellis G, Davidson S, Crotta S, Branzk N, Papayannopoulos V, Wack A. TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection. EMBO Rep. 2015;16:1203-18 pubmed publisher |
| Griseri T, Arnold I, Pearson C, Krausgruber T, Schiering C, Franchini F, et al. Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis. Immunity. 2015;43:187-99 pubmed publisher |
| Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed publisher |
| Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson A, et al. MET is required for the recruitment of anti-tumoural neutrophils. Nature. 2015;522:349-53 pubmed publisher |
| Coffelt S, Kersten K, Doornebal C, Weiden J, Vrijland K, Hau C, et al. IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. Nature. 2015;522:345-348 pubmed publisher |
| Kolaczkowska E, Jenne C, Surewaard B, Thanabalasuriar A, Lee W, Sanz M, et al. Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature. Nat Commun. 2015;6:6673 pubmed publisher |
| Moser E, Hufford M, Braciale T. Late engagement of CD86 after influenza virus clearance promotes recovery in a FoxP3+ regulatory T cell dependent manner. PLoS Pathog. 2014;10:e1004315 pubmed publisher |
| Chen K, Groß C, Sotomayor F, Stacey K, Tschopp J, Sweet M, et al. The neutrophil NLRC4 inflammasome selectively promotes IL-1? maturation without pyroptosis during acute Salmonella challenge. Cell Rep. 2014;8:570-82 pubmed publisher |
| Cipolat S, Hoste E, Natsuga K, Quist S, Watt F. Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility. elife. 2014;3:e01888 pubmed publisher |
| Deshmukh H, Liu Y, Menkiti O, Mei J, Dai N, O Leary C, et al. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat Med. 2014;20:524-30 pubmed publisher |
| Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum R, et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014;124:687-95 pubmed publisher |
| Richter K, Perriard G, Behrendt R, Schwendener R, Sexl V, Dunn R, et al. Macrophage and T cell produced IL-10 promotes viral chronicity. PLoS Pathog. 2013;9:e1003735 pubmed publisher |
| Huang L, Wohlleber D, Reisinger F, Jenne C, Cheng R, Abdullah Z, et al. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol. 2013;14:574-83 pubmed publisher |
| Lee W, Kang J, Yan J, Lee M, Jeon B, Cho S, et al. Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway. PLoS Pathog. 2012;8:e1002614 pubmed publisher |
| Garraud K, Cleret A, Mathieu J, Fiole D, Gauthier Y, Quesnel Hellmann A, et al. Differential role of the interleukin-17 axis and neutrophils in resolution of inhalational anthrax. Infect Immun. 2012;80:131-42 pubmed publisher |
| Edelson B, Bradstreet T, Hildner K, Carrero J, Frederick K, Kc W, et al. CD8?(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes. Immunity. 2011;35:236-48 pubmed publisher |
| Carr K, Sieve A, Indramohan M, Break T, Lee S, Berg R. Specific depletion reveals a novel role for neutrophil-mediated protection in the liver during Listeria monocytogenes infection. Eur J Immunol. 2011;41:2666-76 pubmed publisher |
| Bamboat Z, Ocuin L, Balachandran V, Obaid H, Plitas G, Dematteo R. Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion. J Clin Invest. 2010;120:559-69 pubmed publisher |
