product summary
Loading...
company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CD27
catalog :
BE0348-5MG
quantity :
5 mg
price :
379.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RM27-3E5
reactivity :
mouse
application :
immunoprecipitation, flow cytometry
more info or order :
citations: 6
Reference
Ahrends T, Spanjaard A, Pilzecker B, Bąbała N, Bovens A, Xiao Y, et al. CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness. Immunity. 2017;47:848-861.e5 pubmed publisher
Ngiow S, Young A, Blake S, Hill G, Yagita H, Teng M, et al. Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell-Rich Tumor. Cancer Res. 2016;76:6266-6277 pubmed
Ahrends T, Bąbała N, Xiao Y, Yagita H, Van Eenennaam H, Borst J. CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination. Cancer Res. 2016;76:2921-31 pubmed publisher
Roberts D, Franklin N, Kingeter L, Yagita H, Tutt A, Glennie M, et al. Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells. J Immunother. 2010;33:769-79 pubmed publisher
Sakanishi T, Yagita H. Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice. Biochem Biophys Res Commun. 2010;393:829-35 pubmed publisher
Sumi T, Ishida W, Ojima A, Kajisako M, Sakanishi T, Yagita H, et al. CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice. Immunol Lett. 2008;119:91-6 pubmed publisher
product information
Catalog Number :
BE0348-5MG
Product Name :
InVivoMAb anti-mouse CD27
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
5 mg
Regular Price :
$583.00
Academic Price :
379.00 USD
Clone Name :
RM27-3E5
Isotype :
IgG2a, κ
Immunogen :
Mouse CD27-human IgG1 Fc fusion protein
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo CD27 stimulation, in vitro CD27 stimulation, Immunoprecipitation, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA