product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-human/monkey MDR-1 (CD243)
catalog :
BE0340-25MG
quantity :
25 mg
price :
1,196.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UIC2
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Reference
Szalóki G, Krasznai Z, Toth A, Vizkeleti L, Szöllosi A, Trencsenyi G, et al. The strong in vivo anti-tumor effect of the UIC2 monoclonal antibody is the combined result of Pgp inhibition and antibody dependent cell-mediated cytotoxicity. PLoS ONE. 2014;9:e107875 pubmed publisher
Krasznai Z, Toth A, Mikecz P, Fodor Z, Szabo G, Galuska L, et al. Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG. Eur J Pharm Sci. 2010;41:665-9 pubmed publisher
Goda K, Fenyvesi F, Bacso Z, Nagy H, Marian T, Megyeri A, et al. Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. J Pharmacol Exp Ther. 2007;320:81-8 pubmed
product information
Catalog Number :
BE0340-25MG
Product Name :
InVivoMAb anti-human/monkey MDR-1 (CD243)
Host :
Mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$1,840.00
Academic Price :
1,196.00 USD
Clone Name :
UIC2
Isotype :
IgG2a, κ
Immunogen :
3T3 fibroblasts transfected with human CD243 cDNA
Reactivity :
human/monkey
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models, in vitro MDR-1 blocking, Immunohistochemistry (paraffin)
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA