product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CD172a (SIRPα)
catalog :
BE0322-100MG
quantity :
100 mg
price :
2,548.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
P84
reactivity :
mouse
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
citations: 6
Reference
Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya E, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017;2:e89140 pubmed publisher
Zen K, Guo Y, Bian Z, Lv Z, Zhu D, Ohnishi H, et al. Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state. Nat Commun. 2013;4:2436 pubmed publisher
Koskinen C, Persson E, Baldock P, Stenberg A, Boström I, Matozaki T, et al. Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein ? (SIRP?) signaling. J Biol Chem. 2013;288:29333-44 pubmed publisher
Teraoka Y, Ide K, Morimoto H, Tahara H, Ohdan H. Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRP? inhibitory signaling in mice. PLoS ONE. 2013;8:e58359 pubmed publisher
Lundberg P, Koskinen C, Baldock P, Löthgren H, Stenberg A, Lerner U, et al. Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction. Biochem Biophys Res Commun. 2007;352:444-8 pubmed
Oldenborg P, Gresham H, Lindberg F. CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis. J Exp Med. 2001;193:855-62 pubmed
product information
Catalog Number :
BE0322-100MG
Product Name :
InVivoMAb anti-mouse CD172a (SIRPα)
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$3,920.00
Academic Price :
2,548.00 USD
Clone Name :
P84
Isotype :
IgG1, κ
Immunogen :
Mouse brain membrane protein
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo SIRPα blocking, in vitro SIRPα blocking, Western blot, Immunoprecipitation, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA