product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse TIM-1 (CD365)
catalog :
BE0289-5MG
quantity :
5 mg
price :
379.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
3B3
reactivity :
mouse
application :
ELISA, flow cytometry, activation
more info or order :
citations: 5
Reference
Lee H, Meyer E, Goya S, Pichavant M, Kim H, Bu X, et al. Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity. J Immunol. 2010;185:5225-35 pubmed publisher
Mariat C, Degauque N, Balasubramanian S, Kenny J, DeKruyff R, Umetsu D, et al. Tim-1 signaling substitutes for conventional signal 1 and requires costimulation to induce T cell proliferation. J Immunol. 2009;182:1379-85 pubmed
Degauque N, Mariat C, Kenny J, Zhang D, Gao W, Vu M, et al. Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice. J Clin Invest. 2008;118:735-41 pubmed
Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, et al. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. J Exp Med. 2007;204:1691-702 pubmed
Umetsu S, Lee W, McIntire J, Downey L, Sanjanwala B, Akbari O, et al. TIM-1 induces T cell activation and inhibits the development of peripheral tolerance. Nat Immunol. 2005;6:447-54 pubmed
product information
Catalog Number :
BE0289-5MG
Product Name :
InVivoMAb anti-mouse TIM-1 (CD365)
Host :
rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
5 mg
Regular Price :
$583.00
Academic Price :
379.00 USD
Clone Name :
3B3
Isotype :
IgG2a, κ
Immunogen :
Mouse TIM-1 (signal and IgV domains) mouse IgG2a Fc fusion protein
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo TIM-1 activation, in vitro T cell stimulatioN/Activation, Functional assays, ELISA, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA