product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-human CD4
catalog :
BE0288-25MG
quantity :
25 mg
price :
1,268.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
RPA-T4
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Moolla N, Killick M, Papathanasopoulos M, Capovilla A. Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry. Biochim Biophys Acta. 2016;1860:1854-63 pubmed publisher
Mayer C, Huntenburg J, Nandan A, Schmitt E, Czeloth N, Sparwasser T. CD4 blockade directly inhibits mouse and human CD4(+) T cell functions independent of Foxp3(+) Tregs. J Autoimmun. 2013;47:73-82 pubmed publisher
Toma J, Weinheimer S, Stawiski E, Whitcomb J, Lewis S, Petropoulos C, et al. Loss of asparagine-linked glycosylation sites in variable region 5 of human immunodeficiency virus type 1 envelope is associated with resistance to CD4 antibody ibalizumab. J Virol. 2011;85:3872-80 pubmed publisher
Mack C, Tucker R, Sokol R, Karrer F, Kotzin B, Whitington P, et al. Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Pediatr Res. 2004;56:79-87 pubmed
Geijtenbeek T, Kwon D, Torensma R, van Vliet S, van Duijnhoven G, Middel J, et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell. 2000;100:587-97 pubmed
Moir S, Lapointe R, Malaspina A, Ostrowski M, Cole C, Chun T, et al. CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir. J Virol. 1999;73:7972-80 pubmed
product information
Catalog Number :
BE0288-25MG
Product Name :
InVivoMab anti-human CD4
Host :
mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$1,950.00
Academic Price :
1,268.00 USD
Clone Name :
RPA-T4
Isotype :
IgG1, κ
Reactivity :
human
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vitro CD4 blockade, in vitro blocking of CD4+ T cell activation, Immunofluorescence, Immunohistochemistry (frozen), Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA