product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-human PD-L1 (B7-H1)
catalog :
BE0285-5MG
quantity :
5 mg
price :
379.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
29E.2A3
reactivity :
human
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 7
Reference
Sivakumar R, Chan M, Shin J, Nishida Aoki N, Kenerson H, Elemento O, et al. Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery. Oncoimmunology. 2019;8:e1670019 pubmed publisher
Broos K, Lecocq Q, Keersmaecker B, Raes G, Corthals J, Lion E, et al. Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production. Vaccines (Basel). 2019;7: pubmed publisher
Porichis F, Hart M, Zupkosky J, Barblu L, Kwon D, McMullen A, et al. Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions. J Virol. 2014;88:2508-18 pubmed publisher
Hegde S, Lockridge J, Becker Y, Ma S, Kenney S, Gumperz J. Human NKT cells direct the differentiation of myeloid APCs that regulate T cell responses via expression of programmed cell death ligands. J Autoimmun. 2011;37:28-38 pubmed publisher
Nakamoto N, Cho H, Shaked A, Olthoff K, Valiga M, Kaminski M, et al. Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade. PLoS Pathog. 2009;5:e1000313 pubmed publisher
Cai G, Karni A, Oliveira E, Weiner H, Hafler D, Freeman G. PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells. Cell Immunol. 2004;230:89-98 pubmed
Brown J, Dorfman D, Ma F, Sullivan E, Munoz O, Wood C, et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol. 2003;170:1257-66 pubmed
product information
Catalog Number :
BE0285-5MG
Product Name :
InVivoMab anti-human PD-L1 (B7-H1)
Host :
mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
5 mg
Regular Price :
$583.00
Academic Price :
379.00 USD
Clone Name :
29E.2A3
Isotype :
IgG2b, κ
Immunogen :
Full length human PD-L1
Reactivity :
human
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vitro PD-L1 blockade, Functional assays, Immunohistochemistry (frozen), Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA