product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-mouse IL-3
catalog :
BE0282-100MG
quantity :
100 mg
price :
2,701.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MP2-8F8
reactivity :
mouse
application :
ELISA, flow cytometry
more info or order :
citations: 10
Reference
Anzai A, Mindur J, Halle L, Sano S, Choi J, He S, et al. Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis. J Exp Med. 2019;216:369-383 pubmed publisher
Kamran N, Li Y, Sierra M, Alghamri M, Kadiyala P, Appelman H, et al. Melanoma induced immunosuppression is mediated by hematopoietic dysregulation. Oncoimmunology. 2018;7:e1408750 pubmed publisher
Renner K, Hermann F, Schmidbauer K, Talke Y, Rodriguez Gomez M, Schiechl G, et al. IL-3 contributes to development of lupus nephritis in MRL/lpr mice. Kidney Int. 2015;88:1088-98 pubmed publisher
Li Y, Qi X, Liu B, Huang H. The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance. J Immunol. 2015;194:4328-38 pubmed publisher
Leyva Castillo J, Hener P, Michea P, Karasuyama H, Chan S, Soumelis V, et al. Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade. Nat Commun. 2013;4:2847 pubmed publisher
Shiraishi Y, Jia Y, Domenico J, Joetham A, Karasuyama H, Takeda K, et al. Sequential engagement of Fc?RI on Mast Cells and Basophil Histamine H(4) Receptor and Fc?RI in Allergic Rhinitis. J Immunol. 2013;190:539-48 pubmed publisher
Herbst T, Esser J, Prati M, Kulagin M, Stettler R, Zaiss M, et al. Antibodies and IL-3 support helminth-induced basophil expansion. Proc Natl Acad Sci U S A. 2012;109:14954-9 pubmed publisher
Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting K, et al. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol. 2009;182:2835-41 pubmed publisher
Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman F, Rothenberg M, et al. CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J Immunol. 2006;177:77-83 pubmed
Min B, Prout M, Hu Li J, Zhu J, Jankovic D, Morgan E, et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med. 2004;200:507-17 pubmed
product information
Catalog Number :
BE0282-100MG
Product Name :
InVivoMab anti-mouse IL-3
Host :
rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,155.00
Academic Price :
2,701.00 USD
Clone Name :
MP2-8F8
Isotype :
IgG1
Immunogen :
COS-expressed, recombinant mouse IL-3
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo IL-3 neutralization, in vitro IL-3 neutralization, in vivo IL-3 receptor stimulation (as a complex with IL-3), ELISA, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA