This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-human/monkey CD20
catalog :
BE0276
quantity :
5 mg
price :
300 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2H7
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 6
Reference
Li R, Rezk A, Miyazaki Y, Hilgenberg E, Touil H, Shen P, et al. Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy. Sci Transl Med. 2015;7:310ra166 pubmed publisher
Xiang Y, Peng J, Tai N, Hu C, Zhou Z, Wong F, et al. The dual effects of B cell depletion on antigen-specific T cells in BDC2.5NOD mice. J Immunol. 2012;188:4747-58 pubmed publisher
Mack C, Tucker R, Sokol R, Karrer F, Kotzin B, Whitington P, et al. Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Pediatr Res. 2004;56:79-87 pubmed
Weber M, Prod'homme T, Patarroyo J, Molnarfi N, Karnezis T, Lehmann-Horn K, et al. B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity. Ann Neurol. 2010;68:369-83 pubmed publisher
Polyak M, Deans J. Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure. Blood. 2002;99:3256-62 pubmed
Keren Z, Naor S, Nussbaum S, Golan K, Itkin T, Sasaki Y, et al. B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. Blood. 2011;117:3104-12 pubmed publisher
product information
Catalog Number :
BE0276
Product Name :
InVivoMab anti-human/monkey CD20
Host Species :
mouse
Clonality :
monoclonal
Product Type :
antibody
Size :
5 mg
List Price :
450
Acedemic Discount Price :
300 USD
Clone :
2H7
Isotype :
IgG2b
Specificity :
human, monkey
Application Summary :
in vivo B cell depletion in hCD20 Tg mice, Immunohistochemistry (frozen), Immunoprecipitation, Flow cytometry
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
bxcell.com
1-866-787-3444
headquarters: USA