product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-human/monkey CD20
catalog :
BE0276-100MG
quantity :
100 mg
price :
2,701.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2H7
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 7
Reference
Li R, Rezk A, Miyazaki Y, Hilgenberg E, Touil H, Shen P, et al. Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy. Sci Transl Med. 2015;7:310ra166 pubmed publisher
Hu C, Ding H, Zhang X, Wong F, Wen L. Combination treatment with anti-CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes. Diabetes. 2013;62:2849-58 pubmed publisher
Xiang Y, Peng J, Tai N, Hu C, Zhou Z, Wong F, et al. The dual effects of B cell depletion on antigen-specific T cells in BDC2.5NOD mice. J Immunol. 2012;188:4747-58 pubmed publisher
Keren Z, Naor S, Nussbaum S, Golan K, Itkin T, Sasaki Y, et al. B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. Blood. 2011;117:3104-12 pubmed publisher
Weber M, Prod homme T, Patarroyo J, Molnarfi N, Karnezis T, Lehmann Horn K, et al. B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity. Ann Neurol. 2010;68:369-83 pubmed publisher
Mack C, Tucker R, Sokol R, Karrer F, Kotzin B, Whitington P, et al. Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Pediatr Res. 2004;56:79-87 pubmed
Polyak M, Deans J. Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary struct. Blood. 2002;99:3256-62 pubmed
product information
Catalog Number :
BE0276-100MG
Product Name :
InVivoMab anti-human/monkey CD20
Host :
mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,155.00
Academic Price :
2,701.00 USD
Clone Name :
2H7
Isotype :
IgG2b, κ
Immunogen :
Human tonsillar B cells
Reactivity :
human/monkey
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo B cell depletion in hCD20 Tg mice, Immunohistochemistry (frozen), Immunoprecipitation, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA