product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-mouse TIM-3 (CD366)
catalog :
BE0275-5MG
quantity :
5 mg
price :
379.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
B8.2C12
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 10
Reference
Hsu J, Xia W, Hsu Y, Chan L, Yu W, Cha J, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018;9:1908 pubmed publisher
Wang H, Zhu X, Qin L, Qian H, Wang Y. Microglia activity modulated by T cell Ig and mucin domain protein 3 (Tim-3). Cell Immunol. 2015;293:49-58 pubmed publisher
Hou H, Liu W, Wu S, Lu Y, Peng J, Zhu Y, et al. Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PLoS ONE. 2014;9:e110585 pubmed publisher
Hongo D, Tang X, Baker J, Engleman E, Strober S. Requirement for interactions of natural killer T cells and myeloid-derived suppressor cells for transplantation tolerance. Am J Transplant. 2014;14:2467-77 pubmed publisher
Chabtini L, Mfarrej B, Mounayar M, Zhu B, Batal I, Dakle P, et al. TIM-3 regulates innate immune cells to induce fetomaternal tolerance. J Immunol. 2013;190:88-96 pubmed publisher
Hongo D, Tang X, Dutt S, Nador R, Strober S. Interactions between NKT cells and Tregs are required for tolerance to combined bone marrow and organ transplants. Blood. 2012;119:1581-9 pubmed publisher
Wang F, Wan L, Zhang C, Zheng X, Li J, Chen Z. Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells. Immunobiology. 2009;214:342-9 pubmed publisher
Nakae S, Iikura M, Suto H, Akiba H, Umetsu D, DeKruyff R, et al. TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Blood. 2007;110:2565-8 pubmed
Frisancho Kiss S, Nyland J, Davis S, Barrett M, Gatewood S, Njoku D, et al. Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity. J Immunol. 2006;176:6411-5 pubmed
Monney L, Sabatos C, Gaglia J, Ryu A, Waldner H, Chernova T, et al. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 2002;415:536-41 pubmed
product information
Catalog Number :
BE0275-5MG
Product Name :
InVivoMab anti-mouse TIM-3 (CD366)
Host :
rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
5 mg
Regular Price :
$583.00
Academic Price :
379.00 USD
Clone Name :
B8.2C12
Isotype :
IgG1, κ
Immunogen :
Mouse Tim-3 protein/Freund adjuvant
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo TIM-3 neutralization, in vitro TIM-3 blocking, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA