product summary
Loading...
company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-mouse CD47 (IAP)
catalog :
BE0270-100MG
quantity :
100 mg
price :
2,701.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
miap301
reactivity :
mouse
application :
immunocytochemistry
more info or order :
citations: 13
Reference
Pan Y, Lu F, Fei Q, Yu X, Xiong P, Yu X, et al. Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer. J Hematol Oncol. 2019;12:124 pubmed publisher
Reed M, Luissint A, Azcutia V, Fan S, O Leary M, Quirós M, et al. Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo. Nat Commun. 2019;10:5004 pubmed publisher
Liu M, O Connor R, Trefely S, Graham K, Snyder N, Beatty G. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal. Nat Immunol. 2019;20:265-275 pubmed publisher
Sallets A, Robinson S, Kardosh A, Levy R. Enhancing immunotherapy of STING agonist for lymphoma in preclinical models. Blood Adv. 2018;2:2230-2241 pubmed publisher
Wu L, Yu G, Deng W, Mao L, Yang L, Ma S, et al. Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma. Oncoimmunology. 2018;7:e1397248 pubmed publisher
Xu M, Pu Y, Han D, Shi Y, Cao X, Liang H, et al. Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein ? Signaling. Immunity. 2017;47:363-373.e5 pubmed publisher
Maute R, Gordon S, Mayer A, McCracken M, Natarajan A, Ring N, et al. Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging. Proc Natl Acad Sci U S A. 2015;112:E6506-14 pubmed publisher
Liu X, Pu Y, Cron K, Deng L, Kline J, Frazier W, et al. CD47 blockade triggers T cell-mediated destruction of immunogenic tumors. Nat Med. 2015;21:1209-15 pubmed publisher
Shi L, Bian Z, Chen C, Guo Y, Lv Z, Zeng C, et al. CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production. J Pathol. 2015;237:285-95 pubmed publisher
Hsieh C, Chang W, Lee Y, Huang A. Deficits in cerebellar granule cell development and social interactions in CD47 knockout mice. Dev Neurobiol. 2015;75:463-84 pubmed publisher
Vermeer D, Spanos W, Vermeer P, Bruns A, Lee K, Lee J. Radiation-induced loss of cell surface CD47 enhances immune-mediated clearance of human papillomavirus-positive cancer. Int J Cancer. 2013;133:120-9 pubmed publisher
Majeti R, Chao M, Alizadeh A, Pang W, Jaiswal S, Gibbs K, et al. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell. 2009;138:286-99 pubmed publisher
Chang H, Ma Y, Wan F, Tsai L, Lindberg F, Lee E. Functional blocking of integrin-associated protein impairs memory retention and decreases glutamate release from the hippocampus. Neuroscience. 2001;102:289-96 pubmed
product information
Catalog Number :
BE0270-100MG
Product Name :
InVivoMab anti-mouse CD47 (IAP)
Host :
rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,155.00
Academic Price :
2,701.00 USD
Clone Name :
MIAP301
Isotype :
IgG2a, κ
Immunogen :
Intact CD47 purified from placenta
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo CD47 blockade, in vitro CD47 blockade, Immunofluorescence
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA