product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-mouse CD137 (4-1BB)
catalog :
BE0239-5MG
quantity :
5 mg
price :
350.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
3H3
reactivity :
mouse
more info or order :
citations: 6
Reference
Giardino Torchia M, Munitic I, Castro E, Herz J, McGavern D, Ashwell J. c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival. Eur J Immunol. 2015;45:2672-82 pubmed publisher
Kobayashi T, Doff B, Rearden R, Leggatt G, Mattarollo S. NKT cell-targeted vaccination plus anti-4-1BB antibody generates persistent CD8 T cell immunity against B cell lymphoma. Oncoimmunology. 2015;4:e990793 pubmed
Guillerey C, Ferrari de Andrade L, Vuckovic S, Miles K, Ngiow S, Yong M, et al. Immunosurveillance and therapy of multiple myeloma are CD226 dependent. J Clin Invest. 2015;125:2077-89 pubmed publisher
Tewalt E, Cohen J, Rouhani S, Guidi C, Qiao H, Fahl S, et al. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood. 2012;120:4772-82 pubmed publisher
Verbrugge I, Hagekyriakou J, Sharp L, Galli M, West A, McLaughlin N, et al. Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies. Cancer Res. 2012;72:3163-74 pubmed publisher
Vezys V, Penaloza MacMaster P, Barber D, Ha S, Konieczny B, Freeman G, et al. 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. J Immunol. 2011;187:1634-42 pubmed publisher
product information
Catalog Number :
BE0239-5MG
Product Name :
InVivoMab anti-mouse CD137 (4-1BB)
Host Species :
rat
Clonality :
Monoclonal
Conjugation :
No
Antigen Modification :
No
Product Type :
Antibody
Size :
5 mg
List Price :
$525.00
Acedemic Discount Price :
350.00 USD
list of Pubmed id :
26096449; 25893601; 25949907; 22993390; 22570253; 21742975;
Clone :
3H3
Isotype :
IgG2a
Specificity :
mouse
Concentration :
Lot specific,typically between 2-10 mg/ml
Application Summary :
in vivo 4-1BB stimulation, in vitro 4-1BB stimulation
Storage :
Undiluted at 4°C in the dark
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
bxcell.com
1-866-787-3444
headquarters: USA