product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-human CD3
catalog :
BE0231-100MG
quantity :
100 mg
price :
2,701.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT1 (Leu-4)(T3)
reactivity :
human
application :
flow cytometry
more info or order :
citations: 4
Reference
Wunderlich M, Brooks R, Panchal R, Rhyasen G, Danet Desnoyers G, Mulloy J. OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues. Blood. 2014;123:e134-44 pubmed publisher
Woo J, Lee Y, Neville D, Frankel A. Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials. Methods Mol Biol. 2010;651:157-75 pubmed publisher
Rossi N, Reiné J, Pineda Lezamit M, Pulgar M, Meza N, Swamy M, et al. Differential antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T lymphocytes is conserved in mammals and associated with differential glycosylation. Int Immunol. 2008;20:1247-58 pubmed publisher
Arnett K, Harrison S, Wiley D. Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment. Proc Natl Acad Sci U S A. 2004;101:16268-73 pubmed
product information
Catalog Number :
BE0231-100MG
Product Name :
InVivoMab anti-human CD3
Host :
mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,155.00
Academic Price :
2,701.00 USD
Clone Name :
UCHT1 (Leu-4)(T3)
Isotype :
IgG1, κ
Immunogen :
Human CD3ε
Reactivity :
human
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo T cell depletion in humanized mice, ex vivo T cell inhibition for xenographs, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA