product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-human CD32 (FcγRIIA)
catalog :
BE0224-100MG
quantity :
100 mg
price :
2,701.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IV.3
reactivity :
human
application :
ELISA, flow cytometry
more info or order :
citations: 8
Reference
Walsh T, Harper M, Poole A. SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4. Cell Signal. 2015;27:37-46 pubmed publisher
Flinsenberg T, Janssen W, Herczenik E, Boross P, Nederend M, Jongeneel L, et al. A novel FcγRIIa Q27W gene variant is associated with common variable immune deficiency through defective FcγRIIa downstream signaling. Clin Immunol. 2014;155:108-17 pubmed publisher
Ben Mkaddem S, Hayem G, Jönsson F, Rossato E, Boedec E, Boussetta T, et al. Shifting Fc?RIIA-ITAM from activation to inhibitory configuration ameliorates arthritis. J Clin Invest. 2014;124:3945-59 pubmed publisher
Trist H, Tan P, Wines B, Ramsland P, Orlowski E, Stubbs J, et al. Polymorphisms and interspecies differences of the activating and inhibitory Fc?RII of Macaca nemestrina influence the binding of human IgG subclasses. J Immunol. 2014;192:792-803 pubmed publisher
Stemerding A, Köhl J, Pandey M, Kuipers A, Leusen J, Boross P, et al. Staphylococcus aureus formyl peptide receptor-like 1 inhibitor (FLIPr) and its homologue FLIPr-like are potent Fc?R antagonists that inhibit IgG-mediated effector functions. J Immunol. 2013;191:353-62 pubmed publisher
van der Aar A, Picavet D, Muller F, de Boer L, van Capel T, Zaat S, et al. Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells. J Invest Dermatol. 2013;133:1240-9 pubmed publisher
Veri M, Gorlatov S, Li H, Burke S, Johnson S, Stavenhagen J, et al. Monoclonal antibodies capable of discriminating the human inhibitory Fcgamma-receptor IIB (CD32B) from the activating Fcgamma-receptor IIA (CD32A): biochemical, biological and functional characterization. Immunology. 2007;121:392-404 pubmed
Brown M, King C, Sherren C, Marshall J, Anderson R. A dominant role for FcgammaRII in antibody-enhanced dengue virus infection of human mast cells and associated CCL5 release. J Leukoc Biol. 2006;80:1242-50 pubmed
product information
Catalog Number :
BE0224-100MG
Product Name :
InVivoMab anti-human CD32 (FcγRIIA)
Host :
mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,155.00
Academic Price :
2,701.00 USD
Clone Name :
IV.3
Isotype :
IgG2b
Immunogen :
Human K562 leukemia cell line
Reactivity :
human
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo FcγRIIA blockade in humanized mice, in vitro FcγRIIA blockade, ELISA, Flow cytometry
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA