product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMab anti-mouse CD8β (Lyt 3.2)
catalog :
BE0223-25MG
quantity :
25 mg
price :
1,268.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
53-5.8
reactivity :
mouse
application :
immunocytochemistry, blocking or activating experiments, other
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig 2a
Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed publisher
  • other; mouse; loading ...; fig 2f
Ferrari de Andrade L, Tay R, Pan D, Luoma A, Ito Y, Badrinath S, et al. Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity. Science. 2018;359:1537-1542 pubmed publisher
Noguchi T, Ward J, Gubin M, Arthur C, Lee S, Hundal J, et al. Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape. Cancer Immunol Res. 2017;5:106-117 pubmed publisher
Howland S, Poh C, Rénia L. Activated Brain Endothelial Cells Cross-Present Malaria Antigen. PLoS Pathog. 2015;11:e1004963 pubmed publisher
Kobayashi T, Doff B, Rearden R, Leggatt G, Mattarollo S. NKT cell-targeted vaccination plus anti-4-1BB antibody generates persistent CD8 T cell immunity against B cell lymphoma. Oncoimmunology. 2015;4:e990793 pubmed
Guillerey C, Ferrari de Andrade L, Vuckovic S, Miles K, Ngiow S, Yong M, et al. Immunosurveillance and therapy of multiple myeloma are CD226 dependent. J Clin Invest. 2015;125:2077-89 pubmed publisher
Allard B, Pommey S, Smyth M, Stagg J. Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs. Clin Cancer Res. 2013;19:5626-35 pubmed publisher
Verbrugge I, Hagekyriakou J, Sharp L, Galli M, West A, McLaughlin N, et al. Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies. Cancer Res. 2012;72:3163-74 pubmed publisher
Ahmed K, Wang L, Munegowda M, Mulligan S, Mulligan S, Gordon J, et al. Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling. J Leukoc Biol. 2012;92:289-300 pubmed publisher
Takada K, Jameson S. Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels. J Exp Med. 2009;206:2253-69 pubmed publisher
product information
Catalog Number :
BE0223-25MG
Product Name :
InVivoMab anti-mouse CD8β (Lyt 3.2)
Host :
rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$1,950.00
Academic Price :
1,268.00 USD
Clone Name :
53-5.8
Isotype :
IgG1, κ
Immunogen :
Mouse thymus or spleen
Reactivity :
mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo CD8+ T cell depletion, in vitro CD8 blockade, Immunofluorescence
Recommended Storage Conditions :
The solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA