product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-human CD40
catalog :
BE0189-50MG
quantity :
50 mg
price :
1,966.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G28.5
reactivity :
human
application :
flow cytometry
more info or order :
citations: 9
Reference
Høglund R, Bremel R, Homan E, Torsetnes S, Lossius A, Holmøy T. CD4+ T Cells in the Blood of MS Patients Respond to Predicted Epitopes From B cell Receptors Found in Spinal Fluid. Front Immunol. 2020;11:598 pubmed publisher
Cooley L, Martin R, Zellner H, Irani A, Uram Tuculescu C, El Shikh M, et al. Increased B Cell ADAM10 in Allergic Patients and Th2 Prone Mice. PLoS ONE. 2015;10:e0124331 pubmed publisher
Bankert K, Oxley K, Smith S, Graham J, de Boer M, Thewissen M, et al. Induction of an altered CD40 signaling complex by an antagonistic human monoclonal antibody to CD40. J Immunol. 2015;194:4319-27 pubmed publisher
Okimura K, Maeta K, Kobayashi N, Goto M, Kano N, Ishihara T, et al. Characterization of ASKP1240, a fully human antibody targeting human CD40 with potent immunosuppressive effects. Am J Transplant. 2014;14:1290-9 pubmed publisher
Frentsch M, Stark R, Matzmohr N, Meier S, Durlanik S, Schulz A, et al. CD40L expression permits CD8+ T cells to execute immunologic helper functions. Blood. 2013;122:405-12 pubmed publisher
Dumas G, Dufresne M, Asselin E, Girouard J, Carrier C, Reyes Moreno C. CD40 pathway activation reveals dual function for macrophages in human endometrial cancer cell survival and invasion. Cancer Immunol Immunother. 2013;62:273-83 pubmed publisher
Price A, Tourigny J, Forte E, Salinas R, Dave S, Luftig M. Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-?B activation. J Virol. 2012;86:11096-106 pubmed publisher
D Souza B, Edelstein L, Pegman P, Smith S, Loughran S, Clarke A, et al. Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor. J Virol. 2004;78:1800-16 pubmed
Francisco J, Donaldson K, Chace D, Siegall C, Wahl A. Agonistic properties and in vivo antitumor activity of the anti-CD40 antibody SGN-14. Cancer Res. 2000;60:3225-31 pubmed
product information
Catalog Number :
BE0189-50MG
Product Name :
InVivoMAb anti-human CD40
Host :
Mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
50 mg
Regular Price :
$3,024.00
Academic Price :
1,966.00 USD
Clone Name :
G28.5
Isotype :
G28.5
Immunogen :
Human tonsillar lymphocytes
Reactivity :
Human
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vitro CD40 stimulation, Functional assays, Flow cytometry
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA