product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse IL-17A
catalog :
BE0173-25MG
quantity :
25 mg
price :
1,306.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
17F3
reactivity :
mouse
application :
neutralization, blocking or activating experiments
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig 3s1a
Manils J, Webb L, Howes A, Janzen J, Boeing S, Bowcock A, et al. CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig s1b
Liao Y, Zhao J, Bulek K, Tang F, Chen X, Cai G, et al. Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. Nat Commun. 2020;11:900 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 3b
Le Gars M, Haustant M, Klezovich Bénard M, Paget C, Trottein F, Goossens P, et al. Mechanisms of Invariant NKT Cell Activity in Restraining Bacillus anthracis Systemic Dissemination. J Immunol. 2016;197:3225-3232 pubmed
Faraco G, Brea D, Garcia Bonilla L, Wang G, Racchumi G, Chang H, et al. Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response. Nat Neurosci. 2018;21:240-249 pubmed publisher
Xiong H, Keith J, Samilo D, Carter R, Leiner I, Pamer E. Innate Lymphocyte/Ly6C(hi) Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance. Cell. 2016;165:679-89 pubmed publisher
Coffelt S, Kersten K, Doornebal C, Weiden J, Vrijland K, Hau C, et al. IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. Nature. 2015;522:345-348 pubmed publisher
Sell S, Dietz M, Schneider A, Holtappels R, Mach M, Winkler T. Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 2015;11:e1004481 pubmed publisher
Naik S, Bouladoux N, Linehan J, Han S, Harrison O, Wilhelm C, et al. Commensal-dendritic-cell interaction specifies a unique protective skin immune signature. Nature. 2015;520:104-8 pubmed publisher
Kulcsar K, Baxter V, Greene I, Griffin D. Interleukin 10 modulation of pathogenic Th17 cells during fatal alphavirus encephalomyelitis. Proc Natl Acad Sci U S A. 2014;111:16053-8 pubmed publisher
Khmaladze I, Kelkka T, Guérard S, Wing K, Pizzolla A, Saxena A, et al. Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice. Proc Natl Acad Sci U S A. 2014;111:E3669-78 pubmed publisher
Xin L, Jiang T, Chaturvedi V, Kinder J, Ertelt J, Rowe J, et al. Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2. Proc Natl Acad Sci U S A. 2014;111:10672-7 pubmed publisher
Ermann J, Staton T, Glickman J, de Waal Malefyt R, Glimcher L. Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice. Proc Natl Acad Sci U S A. 2014;111:E2559-66 pubmed publisher
Uddin M, Zhang Y, Harton J, MacNamara K, Avram D. TNF-?-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma. J Immunol. 2014;192:1946-53 pubmed publisher
Berger H, Vegran F, Chikh M, Gilardi F, Ladoire S, Bugaut H, et al. SOCS3 transactivation by PPAR? prevents IL-17-driven cancer growth. Cancer Res. 2013;73:3578-90 pubmed publisher
Gonzalez Lombana C, Gimblet C, Bacellar O, Oliveira W, Passos S, Carvalho L, et al. IL-17 mediates immunopathology in the absence of IL-10 following Leishmania major infection. PLoS Pathog. 2013;9:e1003243 pubmed publisher
Gladiator A, Wangler N, Trautwein Weidner K, LeibundGut Landmann S. Cutting edge: IL-17-secreting innate lymphoid cells are essential for host defense against fungal infection. J Immunol. 2013;190:521-5 pubmed publisher
Valdez P, Vithayathil P, Janelsins B, Shaffer A, Williamson P, Datta S. Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. Immunity. 2012;36:668-79 pubmed publisher
product information
Catalog Number :
BE0173-25MG
Product Name :
InVivoMAb anti-mouse IL-17A
Host :
Mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$2,009.00
Academic Price :
1,306.00 USD
Clone Name :
17F3
Isotype :
17F3
Immunogen :
Mouse IL-17A cross-linked to OVA
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo IL-17A neutralization
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA