product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CTLA-4 (CD152)
catalog :
BE0131-25MG
quantity :
25 mg
price :
1,405.00 USD
clonality :
monoclonal
host :
Syrian golden hamster
conjugate :
nonconjugated
clone name :
9H10
reactivity :
mouse
application :
western blot, immunohistochemistry
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig s5
Zhong W, Myers J, Wang F, Wang K, Lucas J, Rosfjord E, et al. Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors. BMC Genomics. 2020;21:2 pubmed publisher
Ariyan C, Brady M, Siegelbaum R, Hu J, Bello D, Rand J, et al. Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade. Cancer Immunol Res. 2018;6:189-200 pubmed publisher
Gao J, Shi L, Zhao H, Chen J, Xiong L, He Q, et al. Loss of IFN-? Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy. Cell. 2016;167:397-404.e9 pubmed publisher
Bartkowiak T, Singh S, Yang G, Galvan G, Haria D, Ai M, et al. Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine. Proc Natl Acad Sci U S A. 2015;112:E5290-9 pubmed publisher
Spranger S, Bao R, Gajewski T. Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity. Nature. 2015;523:231-5 pubmed publisher
Twyman Saint Victor C, Rech A, Maity A, Rengan R, Pauken K, Stelekati E, et al. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature. 2015;520:373-7 pubmed publisher
Stephan S, Taber A, Jileaeva I, Pegues E, Sentman C, Stephan M. Biopolymer implants enhance the efficacy of adoptive T-cell therapy. Nat Biotechnol. 2015;33:97-101 pubmed publisher
Ozdemir B, Pentcheva Hoang T, Carstens J, Zheng X, Wu C, Simpson T, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014;25:719-34 pubmed publisher
Krummey S, Floyd T, Liu D, Wagener M, Song M, Ford M. Candida-elicited murine Th17 cells express high Ctla-4 compared with Th1 cells and are resistant to costimulation blockade. J Immunol. 2014;192:2495-504 pubmed publisher
Goding S, Wilson K, Xie Y, Harris K, Baxi A, Akpinarli A, et al. Restoring immune function of tumor-specific CD4+ T cells during recurrence of melanoma. J Immunol. 2013;190:4899-909 pubmed publisher
Hervieu A, Rébé C, Vegran F, Chalmin F, Bruchard M, Vabres P, et al. Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth. J Invest Dermatol. 2013;133:499-508 pubmed publisher
Waitz R, Solomon S, Petre E, Trumble A, Fassò M, Norton L, et al. Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy. Cancer Res. 2012;72:430-9 pubmed publisher
Balachandran V, Cavnar M, Zeng S, Bamboat Z, Ocuin L, Obaid H, et al. Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido. Nat Med. 2011;17:1094-100 pubmed publisher
Pedicord V, Montalvo W, Leiner I, Allison J. Single dose of anti-CTLA-4 enhances CD8+ T-cell memory formation, function, and maintenance. Proc Natl Acad Sci U S A. 2011;108:266-71 pubmed publisher
Quezada S, Simpson T, Peggs K, Merghoub T, Vider J, Fan X, et al. Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med. 2010;207:637-50 pubmed publisher
product information
Catalog Number :
BE0131-25MG
Product Name :
InVivoMAb anti-mouse CTLA-4 (CD152)
Host :
Syrian Hamster
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$2,162.00
Academic Price :
1,405.00 USD
Clone Name :
9H10
Isotype :
9H10
Immunogen :
Mouse CTLA-4-human IgG1 fusion protein
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Western blot
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA