product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse Ly6G
catalog :
BE0075-1-1MG
quantity :
1 mg
price :
107.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RB6-8C5
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 33
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig 5b
Zhang G, Li M, Zhou D, Yang X, Zhang W, Gao R. Loss of endothelial EMCN drives tumor lung metastasis through the premetastatic niche. J Transl Med. 2022;20:446 pubmed publisher
  • blocking or activating experiments; mouse; fig 4d
Fischer A, Wannemacher J, Christ S, Koopmans T, Kadri S, Zhao J, et al. Neutrophils direct preexisting matrix to initiate repair in damaged tissues. Nat Immunol. 2022;23:518-531 pubmed publisher
  • blocking or activating experiments; mouse; fig s6a
Wutschka J, Kast B, Sator Schmitt M, Appak Baskoy S, Hess J, Sinn H, et al. JUNB suppresses distant metastasis by influencing the initial metastatic stage. Clin Exp Metastasis. 2021;38:411-423 pubmed publisher
  • blocking or activating experiments; mouse; ; fig 2f
Uyanik B, Goloudina A, Akbarali A, Grigorash B, Petukhov A, Singhal S, et al. Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses. Nat Commun. 2021;12:3622 pubmed publisher
  • blocking or activating experiments; mouse; fig 5d
Uhl B, Braun C, Dominik J, Luft J, Canis M, Reichel C. A Novel Experimental Approach for In Vivo Analyses of the Salivary Gland Microvasculature. Front Immunol. 2020;11:604470 pubmed publisher
  • blocking or activating experiments; mouse; fig 1d
Lim C, Or Y, Ong Z, Chung H, Hayashi H, Shrestha S, et al. Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig s7a
Bosiljcic M, Cederberg R, Hamilton M, Lepard N, Harbourne B, Collier J, et al. Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs. Breast Cancer Res. 2019;21:103 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 2b
Spolski R, West E, Li P, Veenbergen S, Yung S, Kazemian M, et al. IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1a
Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019;567:249-252 pubmed publisher
  • blocking or activating experiments; mouse; fig 4c
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4b
  • flow cytometry; mouse; loading ...; fig 4a
Abeln M, Albers I, Peters Bernard U, Flächsig Schulz K, Kats E, Kispert A, et al. Sialic acid is a critical fetal defense against maternal complement attack. J Clin Invest. 2019;129:422-436 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 6b
Kwan B, Zhu E, Tzeng A, Sugito H, Eltahir A, Ma B, et al. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. J Exp Med. 2017;214:1679-1690 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 7i
Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher
Davis R, Snyder E, Miller J, Carter S, Houser C, Klampatsa A, et al. Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy. Photochem Photobiol. 2019;95:430-438 pubmed publisher
Moynihan K, Opel C, Szeto G, Tzeng A, Zhu E, Engreitz J, et al. Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nat Med. 2016;22:1402-1410 pubmed publisher
Chorny A, Casas Recasens S, Sintes J, Shan M, Polentarutti N, García Escudero R, et al. The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells. J Exp Med. 2016;213:2167-85 pubmed publisher
Jorgensen I, Zhang Y, Krantz B, Miao E. Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. J Exp Med. 2016;213:2113-28 pubmed publisher
Ellis G, Davidson S, Crotta S, Branzk N, Papayannopoulos V, Wack A. TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection. EMBO Rep. 2015;16:1203-18 pubmed publisher
Griseri T, Arnold I, Pearson C, Krausgruber T, Schiering C, Franchini F, et al. Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis. Immunity. 2015;43:187-99 pubmed publisher
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed publisher
Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson A, et al. MET is required for the recruitment of anti-tumoural neutrophils. Nature. 2015;522:349-53 pubmed publisher
Coffelt S, Kersten K, Doornebal C, Weiden J, Vrijland K, Hau C, et al. IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. Nature. 2015;522:345-348 pubmed publisher
Yamada D, Elsaesser H, Lux A, Timmerman J, Morrison S, de la Torre J, et al. Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection. Immunity. 2015;42:379-390 pubmed publisher
Moser E, Hufford M, Braciale T. Late engagement of CD86 after influenza virus clearance promotes recovery in a FoxP3+ regulatory T cell dependent manner. PLoS Pathog. 2014;10:e1004315 pubmed publisher
Chen K, Groß C, Sotomayor F, Stacey K, Tschopp J, Sweet M, et al. The neutrophil NLRC4 inflammasome selectively promotes IL-1? maturation without pyroptosis during acute Salmonella challenge. Cell Rep. 2014;8:570-82 pubmed publisher
Deshmukh H, Liu Y, Menkiti O, Mei J, Dai N, O Leary C, et al. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat Med. 2014;20:524-30 pubmed publisher
Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum R, et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014;124:687-95 pubmed publisher
Richter K, Perriard G, Behrendt R, Schwendener R, Sexl V, Dunn R, et al. Macrophage and T cell produced IL-10 promotes viral chronicity. PLoS Pathog. 2013;9:e1003735 pubmed publisher
Huang L, Wohlleber D, Reisinger F, Jenne C, Cheng R, Abdullah Z, et al. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol. 2013;14:574-83 pubmed publisher
Lee W, Kang J, Yan J, Lee M, Jeon B, Cho S, et al. Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway. PLoS Pathog. 2012;8:e1002614 pubmed publisher
Garraud K, Cleret A, Mathieu J, Fiole D, Gauthier Y, Quesnel Hellmann A, et al. Differential role of the interleukin-17 axis and neutrophils in resolution of inhalational anthrax. Infect Immun. 2012;80:131-42 pubmed publisher
Edelson B, Bradstreet T, Hildner K, Carrero J, Frederick K, Kc W, et al. CD8?(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes. Immunity. 2011;35:236-48 pubmed publisher
Carr K, Sieve A, Indramohan M, Break T, Lee S, Berg R. Specific depletion reveals a novel role for neutrophil-mediated protection in the liver during Listeria monocytogenes infection. Eur J Immunol. 2011;41:2666-76 pubmed publisher
Bamboat Z, Ocuin L, Balachandran V, Obaid H, Plitas G, Dematteo R. Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion. J Clin Invest. 2010;120:559-69 pubmed publisher
product information
Catalog Number :
BE0075-1-1MG
Product Name :
InVivoMAb anti-mouse Ly6G
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
1 mg
Regular Price :
$164.00
Academic Price :
107.00 USD
Clone Name :
RB6-8C5
Isotype :
1A8
Immunogen :
EL4J cells transfected with Ly6G
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo neutrophil depletion, in vivo MDSC depletion, Immunofluorescence, Immunohistochemistry (paraffin), Immunohistochemistry (frozen), Flow cytometry
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA