product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse TNFα
catalog :
BE0058-50MG
quantity :
50 mg
price :
1,966.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
XT3.11
reactivity :
mouse
application :
western blot, flow cytometry, blocking or activating experiments
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Lissner M, Cumnock K, Davis N, Vilches Moure J, Basak P, Navarrete D, et al. Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Fernandes R, Li C, Wang G, Yang X, Savvides C, Glassman C, et al. Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; fig 4c
Robbins Y, Greene S, Friedman J, Clavijo P, Van Waes C, Fabian K, et al. Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; fig 8a
Manils J, Webb L, Howes A, Janzen J, Boeing S, Bowcock A, et al. CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation. elife. 2020;9: pubmed publisher
Sasaki K, Himeno A, Nakagawa T, Sasaki Y, Kiyonari H, Iwai K. Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nat Commun. 2019;10:3878 pubmed publisher
Wang A, Pope S, Weinstein J, Yu S, Zhang C, Booth C, et al. Specific sequences of infectious challenge lead to secondary hemophagocytic lymphohistiocytosis-like disease in mice. Proc Natl Acad Sci U S A. 2019;116:2200-2209 pubmed publisher
Dunkel J, Viitala M, Karikoski M, Rantakari P, Virtakoivu R, Elima K, et al. Enhanced Antibody Production in Clever-1/Stabilin-1-Deficient Mice. Front Immunol. 2018;9:2257 pubmed publisher
Shaabani N, Honke N, Nguyen N, Huang Z, Arimoto K, Lazar D, et al. The probacterial effect of type I interferon signaling requires its own negative regulator USP18. Sci Immunol. 2018;3: pubmed publisher
Habtetsion T, Ding Z, Pi W, Li T, Lu C, Chen T, et al. Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death. Cell Metab. 2018;28:228-242.e6 pubmed publisher
Wang G, Biswas A, Ma W, Kandpal M, Coker C, Grandgenett P, et al. Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle. Nat Med. 2018;24:770-781 pubmed publisher
Valentin Torres A, Savarin C, Barnett J, Bergmann C. Blockade of sustained tumor necrosis factor in a transgenic model of progressive autoimmune encephalomyelitis limits oligodendrocyte apoptosis and promotes oligodendrocyte maturation. J Neuroinflammation. 2018;15:121 pubmed publisher
Dillen C, Pinsker B, Marusina A, Merleev A, Farber O, Liu H, et al. Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. J Clin Invest. 2018;128:1026-1042 pubmed publisher
Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
Gong Y, Guy C, Olauson H, Becker J, Yang M, Fitzgerald P, et al. ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences. Cell. 2017;169:286-300.e16 pubmed publisher
Kugler D, Flomerfelt F, Costa D, Laky K, Kamenyeva O, Mittelstadt P, et al. Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes. J Exp Med. 2016;213:3041-3056 pubmed
Webb L, Ley S, Seddon B. TNF activation of NF-κB is essential for development of single-positive thymocytes. J Exp Med. 2016;213:1399-407 pubmed publisher
Grinberg Bleyer Y, Dainichi T, Oh H, Heise N, Klein U, Schmid R, et al. Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin. J Immunol. 2015;194:2472-6 pubmed publisher
Baeyens A, Saadoun D, Billiard F, Rouers A, Grégoire S, Zaragoza B, et al. Effector T cells boost regulatory T cell expansion by IL-2, TNF, OX40, and plasmacytoid dendritic cells depending on the immune context. J Immunol. 2015;194:999-1010 pubmed publisher
Christensen A, Skov S, Kvist P, Haase C. Depletion of regulatory T cells in a hapten-induced inflammation model results in prolonged and increased inflammation driven by T cells. Clin Exp Immunol. 2015;179:485-99 pubmed publisher
Yoo J, Braciale T. IL-21 promotes late activator APC-mediated T follicular helper cell differentiation in experimental pulmonary virus infection. PLoS ONE. 2014;9:e105872 pubmed publisher
Maltby S, Hansbro N, Tay H, Stewart J, Plank M, Donges B, et al. Production and differentiation of myeloid cells driven by proinflammatory cytokines in response to acute pneumovirus infection in mice. J Immunol. 2014;193:4072-82 pubmed publisher
Deberge M, Ely K, Enelow R. Soluble, but not transmembrane, TNF-? is required during influenza infection to limit the magnitude of immune responses and the extent of immunopathology. J Immunol. 2014;192:5839-51 pubmed publisher
Beug S, Tang V, LaCasse E, Cheung H, Beauregard C, Brun J, et al. Smac mimetics and innate immune stimuli synergize to promote tumor death. Nat Biotechnol. 2014;32:182-90 pubmed publisher
Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum R, et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014;124:687-95 pubmed publisher
Dietze K, Zelinskyy G, Liu J, Kretzmer F, Schimmer S, Dittmer U. Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loads. PLoS Pathog. 2013;9:e1003798 pubmed publisher
Weinlich R, Oberst A, Dillon C, Janke L, Milasta S, Lukens J, et al. Protective roles for caspase-8 and cFLIP in adult homeostasis. Cell Rep. 2013;5:340-8 pubmed publisher
Kugler D, Mittelstadt P, Ashwell J, Sher A, Jankovic D. CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection. J Exp Med. 2013;210:1919-27 pubmed publisher
Bradley L, Douglass M, Chatterjee D, Akira S, Baaten B. Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced toll-like receptor signaling. PLoS Pathog. 2012;8:e1002641 pubmed publisher
Quezada S, Simpson T, Peggs K, Merghoub T, Vider J, Fan X, et al. Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med. 2010;207:637-50 pubmed publisher
product information
Catalog Number :
BE0058-50MG
Product Name :
InVivoMAb anti-mouse TNFα
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
50 mg
Regular Price :
$3,024.00
Academic Price :
1,966.00 USD
Clone Name :
XT3.11
Isotype :
XT3.11
Immunogen :
Recombinant mouse TNFα
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo TNFα neutralization, in vitro TNFα neutralization, Western blot
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA