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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse IFNγ
catalog :
BE0055-1MG
quantity :
1 mg
price :
107.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
XMG1.2
reactivity :
mouse
application :
western blot, flow cytometry, blocking or activating experiments, other
more info or order :
citations: 56
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; 10 ug/ml; loading ...; fig 5b
Garnier L, Pick R, Montorfani J, Sun M, Brighouse D, Liaudet N, et al. IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis. Sci Adv. 2022;8:eabl5162 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Gao L, Li B, Wang J, Shen D, Yang M, Sun R, et al. Activation of Liver X Receptor α Sensitizes Mice to T-Cell Mediated Hepatitis. Hepatol Commun. 2020;4:1664-1679 pubmed publisher
  • flow cytometry; mouse; loading ...
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
  • blocking or activating experiments; mouse; fig 4c
Robbins Y, Greene S, Friedman J, Clavijo P, Van Waes C, Fabian K, et al. Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3f
Zhou T, Damsky W, Weizman O, McGeary M, Hartmann K, Rosen C, et al. IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy. Nature. 2020;583:609-614 pubmed publisher
  • other; mouse
Koprivsek J, He Y, Song C, Zhang N, Tumanov A, Zhong G. Evasion of Innate Lymphoid Cell-Regulated Gamma Interferon Responses by Chlamydia muridarum To Achieve Long-Lasting Colonization in Mouse Colon. Infect Immun. 2020;88: pubmed publisher
  • blocking or activating experiments; mouse; 10 ug/ml; loading ...; fig s2
Hu X, Majchrzak K, Liu X, Wyatt M, Spooner C, Moisan J, et al. In Vitro Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness In Vivo. Cancer Res. 2018;78:3888-3898 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 3d
Le Gars M, Haustant M, Klezovich Bénard M, Paget C, Trottein F, Goossens P, et al. Mechanisms of Invariant NKT Cell Activity in Restraining Bacillus anthracis Systemic Dissemination. J Immunol. 2016;197:3225-3232 pubmed
Lee J, Hall J, Kroehling L, Wu L, Najar T, Nguyen H, et al. Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease. Cell. 2020;180:79-91.e16 pubmed publisher
Etxeberria I, Bolaños E, Quetglas J, Gros A, Villanueva A, Palomero J, et al. Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells. Cancer Cell. 2019;36:613-629.e7 pubmed publisher
LaFleur M, Nguyen T, Coxe M, Miller B, Yates K, Gillis J, et al. PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity. Nat Immunol. 2019;20:1335-1347 pubmed publisher
Gaylo Moynihan A, Prizant H, Popovic M, Fernandes N, Anderson C, Chiou K, et al. Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites. Immunity. 2019;51:298-309.e6 pubmed publisher
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed publisher
Wang A, Pope S, Weinstein J, Yu S, Zhang C, Booth C, et al. Specific sequences of infectious challenge lead to secondary hemophagocytic lymphohistiocytosis-like disease in mice. Proc Natl Acad Sci U S A. 2019;116:2200-2209 pubmed publisher
Andre P, Denis C, Soulas C, Bourbon Caillet C, Lopez J, Arnoux T, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018;175:1731-1743.e13 pubmed publisher
Uche U, Piccirillo A, Kataoka S, Grebinoski S, D Cruz L, Kane L. PIK3IP1/TrIP restricts activation of T cells through inhibition of PI3K/Akt. J Exp Med. 2018;215:3165-3179 pubmed publisher
Gopal R, Lee B, McHugh K, Rich H, Ramanan K, Mandalapu S, et al. STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection. Front Immunol. 2018;9:2151 pubmed publisher
Giles D, Duncker P, Wilkinson N, Washnock Schmid J, Segal B. CNS-resident classical DCs play a critical role in CNS autoimmune disease. J Clin Invest. 2018;128:5322-5334 pubmed publisher
Taylor S, Mehina E, White E, Reeson P, Yongblah K, Doyle K, et al. Suppressing Interferon-γ Stimulates Microglial Responses and Repair of Microbleeds in the Diabetic Brain. J Neurosci. 2018;38:8707-8722 pubmed publisher
Singh M, Ni M, Sullivan J, Hamerman J, Campbell D. B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation. J Exp Med. 2018;215:2429-2443 pubmed publisher
Wang Z, Yin W, Zhu L, Li J, Yao Y, Chen F, et al. Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production. Immunity. 2018;49:80-92.e7 pubmed publisher
Tanaka S, Jiang Y, Martinez G, Tanaka K, Yan X, Kurosaki T, et al. Trim33 mediates the proinflammatory function of Th17 cells. J Exp Med. 2018;215:1853-1868 pubmed publisher
Zheng X, Fang Z, Liu X, Deng S, Zhou P, Wang X, et al. Increased vessel perfusion predicts the efficacy of immune checkpoint blockade. J Clin Invest. 2018;128:2104-2115 pubmed publisher
Oleinika K, Rosser E, Matei D, Nistala K, Bosma A, Drozdov I, et al. CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells. Nat Commun. 2018;9:684 pubmed publisher
Xu M, Pokrovskii M, Ding Y, Yi R, Au C, Harrison O, et al. c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont. Nature. 2018;554:373-377 pubmed publisher
Dillen C, Pinsker B, Marusina A, Merleev A, Farber O, Liu H, et al. Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. J Clin Invest. 2018;128:1026-1042 pubmed publisher
Ullrich E, Abendroth B, Rothamer J, Huber C, Büttner Herold M, Buchele V, et al. BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease. J Clin Invest. 2018;128:916-930 pubmed publisher
Delong J, Hall A, Konradt C, Coppock G, Park J, Harms Pritchard G, et al. Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1. J Immunol. 2018;200:1761-1770 pubmed publisher
Glasner A, Levi A, Enk J, Isaacson B, Viukov S, Orlanski S, et al. NKp46 Receptor-Mediated Interferon-? Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis. Immunity. 2018;48:107-119.e4 pubmed publisher
Duncker P, Stoolman J, Huber A, Segal B. GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction. J Immunol. 2018;200:966-973 pubmed publisher
Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, et al. IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. Nature. 2017;551:110-114 pubmed publisher
Malik S, Sadhu S, Elesela S, Pandey R, Chawla A, Sharma D, et al. Transcription factor Foxo1 is essential for IL-9 induction in T helper cells. Nat Commun. 2017;8:815 pubmed publisher
Skyberg J, Lacey C. Hematopoietic MyD88 and IL-18 are essential for IFN-?-dependent restriction of type A Francisella tularensis infection. J Leukoc Biol. 2017;102:1441-1450 pubmed publisher
Na H, Lim H, Choi G, Kim B, Kim S, Chang Y, et al. Concomitant suppression of TH2 and TH17 cell responses in allergic asthma by targeting retinoic acid receptor-related orphan receptor ?t. J Allergy Clin Immunol. 2018;141:2061-2073.e5 pubmed publisher
Simeonov D, Gowen B, Boontanrart M, Roth T, Gagnon J, Mumbach M, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. 2017;549:111-115 pubmed publisher
Ye J, Wang Y, Liu X, Li L, Opejin A, Hsueh E, et al. TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy. J Immunol. 2017;199:941-954 pubmed publisher
Montoya M, Maul J, Singh P, Pua H, Dahlström F, Wu N, et al. A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation. J Immunol. 2017;199:559-569 pubmed publisher
Amet T, Son Y, Jiang L, Cheon I, Huang S, Gupta S, et al. BCL6 represses antiviral resistance in follicular T helper cells. J Leukoc Biol. 2017;102:527-536 pubmed publisher
Kugler D, Flomerfelt F, Costa D, Laky K, Kamenyeva O, Mittelstadt P, et al. Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes. J Exp Med. 2016;213:3041-3056 pubmed
Clever D, Roychoudhuri R, Constantinides M, Askenase M, Sukumar M, Klebanoff C, et al. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016;166:1117-1131.e14 pubmed publisher
Kannan Y, Li Y, Coomes S, Okoye I, Pelly V, Sriskantharajah S, et al. Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells. J Allergy Clin Immunol. 2017;139:655-666.e7 pubmed publisher
Hou L, Cooley J, Swanson R, Ong P, Pike R, Bogyo M, et al. The protease cathepsin L regulates Th17 cell differentiation. J Autoimmun. 2015;65:56-63 pubmed publisher
Choi Y, Gullicksrud J, Xing S, Zeng Z, Shan Q, Li F, et al. LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nat Immunol. 2015;16:980-90 pubmed publisher
Zander R, Obeng Adjei N, Guthmiller J, Kulu D, Li J, Ongoiba A, et al. PD-1 Co-inhibitory and OX40 Co-stimulatory Crosstalk Regulates Helper T Cell Differentiation and Anti-Plasmodium Humoral Immunity. Cell Host Microbe. 2015;17:628-41 pubmed publisher
Sell S, Dietz M, Schneider A, Holtappels R, Mach M, Winkler T. Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 2015;11:e1004481 pubmed publisher
Cao A, Yao S, Gong B, Nurieva R, Elson C, Cong Y. Interleukin (IL)-21 promotes intestinal IgA response to microbiota. Mucosal Immunol. 2015;8:1072-82 pubmed publisher
Gu A, Zhang S, Wang Y, Xiong H, Curtis T, Wan Y. A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling. Immunity. 2015;42:68-79 pubmed publisher
Bertin S, Aoki Nonaka Y, de Jong P, Nohara L, Xu H, Stanwood S, et al. The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4? T cells. Nat Immunol. 2014;15:1055-1063 pubmed publisher
Rabenstein H, Behrendt A, Ellwart J, Naumann R, Horsch M, Beckers J, et al. Differential kinetics of antigen dependency of CD4+ and CD8+ T cells. J Immunol. 2014;192:3507-17 pubmed publisher
Uddin M, Zhang Y, Harton J, MacNamara K, Avram D. TNF-?-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma. J Immunol. 2014;192:1946-53 pubmed publisher
Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum R, et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014;124:687-95 pubmed publisher
Kugler D, Mittelstadt P, Ashwell J, Sher A, Jankovic D. CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection. J Exp Med. 2013;210:1919-27 pubmed publisher
Simons D, Oh S, Kropf E, Aitken M, Garcia V, Basehoar A, et al. Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis. J Immunol. 2013;190:3134-41 pubmed publisher
Yu X, Guo C, Yi H, Qian J, Fisher P, Subjeck J, et al. A multifunctional chimeric chaperone serves as a novel immune modulator inducing therapeutic antitumor immunity. Cancer Res. 2013;73:2093-103 pubmed publisher
Mohr E, Cunningham A, Toellner K, Bobat S, Coughlan R, Bird R, et al. IFN-{gamma} produced by CD8 T cells induces T-bet-dependent and -independent class switching in B cells in responses to alum-precipitated protein vaccine. Proc Natl Acad Sci U S A. 2010;107:17292-7 pubmed publisher
Quezada S, Simpson T, Peggs K, Merghoub T, Vider J, Fan X, et al. Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med. 2010;207:637-50 pubmed publisher
product information
Catalog Number :
BE0055-1MG
Product Name :
InVivoMAb anti-mouse IFNγ
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
1 mg
Regular Price :
$164.00
Academic Price :
107.00 USD
Clone Name :
XMG1.2
Isotype :
XMG1.2
Immunogen :
Recombinant mouse IFNγ
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo IFNγ neutralization, in vitro IFNγ neutralization, ELISPOT, Flow cytometry, Western blot
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA