product summary
Loading...
company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse IL-12 p40
catalog :
BE0051-50MG
quantity :
50 mg
price :
1,966.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
C17.8
reactivity :
mouse
application :
western blot, ELISA, immunoprecipitation, flow cytometry, blocking or activating experiments
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig s3a
Wang R, Graham S, Sun N, McCarthy D, Peng R, Erickson J, et al. CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40. PLoS ONE. 2020;15:e0228221 pubmed publisher
Dann S, Le C, Hanson E, Ross M, Eckmann L. Giardia Infection of the Small Intestine Induces Chronic Colitis in Genetically Susceptible Hosts. J Immunol. 2018;201:548-559 pubmed publisher
Villegas Mendez A, Shaw T, Inkson C, Strangward P, de Souza J, Couper K. Parasite-Specific CD4+ IFN-γ+ IL-10+ T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection. Infect Immun. 2016;84:34-46 pubmed publisher
Brunner P, Glitzner E, Reininger B, Klein I, Stary G, Mildner M, et al. CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin. Exp Dermatol. 2015;24:522-8 pubmed publisher
Ruffell B, Chang Strachan D, Chan V, Rosenbusch A, Ho C, Pryer N, et al. Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Cancer Cell. 2014;26:623-37 pubmed publisher
Tang W, Wang H, Claudio E, Tassi I, Ha H, Saret S, et al. The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells. Immunity. 2014;41:555-66 pubmed publisher
Deligne C, Metidji A, Fridman W, Teillaud J. Anti-CD20 therapy induces a memory Th1 response through the IFN-γ/IL-12 axis and prevents protumor regulatory T-cell expansion in mice. Leukemia. 2015;29:947-57 pubmed publisher
Tarrio M, Lee S, Fragoso M, Sun H, Kanno Y, O Shea J, et al. Proliferation conditions promote intrinsic changes in NK cells for an IL-10 response. J Immunol. 2014;193:354-63 pubmed publisher
Abdi K, Singh N, Spooner E, Kessler B, Radaev S, Lantz L, et al. Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly. J Immunol. 2014;192:6028-36 pubmed publisher
Chappert P, Bouladoux N, Naik S, Schwartz R. Specific gut commensal flora locally alters T cell tuning to endogenous ligands. Immunity. 2013;38:1198-210 pubmed publisher
Villegas Mendez A, de Souza J, Lavelle S, Gwyer Findlay E, Shaw T, Van Rooijen N, et al. IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog. 2013;9:e1003293 pubmed publisher
Gwyer Findlay E, Villegas Mendez A, de Souza J, Inkson C, Shaw T, Saris C, et al. IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection. J Immunol. 2013;190:4553-61 pubmed publisher
Yu X, Guo C, Yi H, Qian J, Fisher P, Subjeck J, et al. A multifunctional chimeric chaperone serves as a novel immune modulator inducing therapeutic antitumor immunity. Cancer Res. 2013;73:2093-103 pubmed publisher
Prabhakara R, Harro J, Leid J, Keegan A, Prior M, Shirtliff M. Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus. Infect Immun. 2011;79:5010-8 pubmed publisher
Mack E, Kallal L, Demers D, Biron C. Type 1 interferon induction of natural killer cell gamma interferon production for defense during lymphocytic choriomeningitis virus infection. MBio. 2011;2: pubmed publisher
Massacand J, Stettler R, Meier R, Humphreys N, Grencis R, Marsland B, et al. Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function. Proc Natl Acad Sci U S A. 2009;106:13968-73 pubmed publisher
product information
Catalog Number :
BE0051-50MG
Product Name :
InVivoMAb anti-mouse IL-12 p40
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
50 mg
Regular Price :
$3,024.00
Academic Price :
1,966.00 USD
Clone Name :
C17.8
Isotype :
C17.8
Immunogen :
Recombinant mouse IL-12 p70
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo IL-12p40 neutralization, p40 affinity chromatography, Immunoprecipitation, ELISA, Flow cytometry, Western blot
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA