product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse IL-6R
catalog :
BE0047-1MG
quantity :
1 mg
price :
107.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
15A7
reactivity :
mouse
application :
other
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • other; mouse
Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019;567:249-252 pubmed publisher
Tsukamoto H, Senju S, Matsumura K, Swain S, Nishimura Y. IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age. Nat Commun. 2015;6:6702 pubmed publisher
Barber D, Andrade B, McBerry C, Sereti I, Sher A. Role of IL-6 in Mycobacterium avium--associated immune reconstitution inflammatory syndrome. J Immunol. 2014;192:676-82 pubmed publisher
Pham D, Walline C, Hollister K, Dent A, Blum J, Firulli A, et al. The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor ? chain. J Biol Chem. 2013;288:27423-33 pubmed publisher
Markey K, Koyama M, Kuns R, Lineburg K, Wilson Y, Olver S, et al. Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood. 2012;119:5918-30 pubmed publisher
Piconese S, Gri G, Tripodo C, Musio S, Gorzanelli A, Frossi B, et al. Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation. Blood. 2009;114:2639-48 pubmed publisher
product information
Catalog Number :
BE0047-1MG
Product Name :
InVivoMAb anti-mouse IL-6R
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
1 mg
Regular Price :
$164.00
Academic Price :
107.00 USD
Clone Name :
15A7
Isotype :
15A7
Immunogen :
OKT-4 hybridoma cells
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo blocking of IL-6/IL-6R signaling, in vitro blocking of IL-6R signaling
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA