product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse IL-2
catalog :
BE0043-1-25MG
quantity :
25 mg
price :
1,306.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
JES6-1A12
reactivity :
mouse
more info or order :
citations: 16
Reference
Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed publisher
Davies A, Kim H, González Cano R, Choi J, Back S, Roh S, et al. Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury. Cell. 2019;176:716-728.e18 pubmed publisher
Uche U, Piccirillo A, Kataoka S, Grebinoski S, D Cruz L, Kane L. PIK3IP1/TrIP restricts activation of T cells through inhibition of PI3K/Akt. J Exp Med. 2018;215:3165-3179 pubmed publisher
Olson M, Ulrich B, Hummel S, Khan I, Meuris B, Cherukuri Y, et al. Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production. J Immunol. 2017;198:4352-4359 pubmed publisher
Holt M, Punkosdy G, Glass D, Shevach E. TCR Signaling and CD28/CTLA-4 Signaling Cooperatively Modulate T Regulatory Cell Homeostasis. J Immunol. 2017;198:1503-1511 pubmed publisher
Littwitz Salomon E, Akhmetzyanova I, Vallet C, Francois S, Dittmer U, Gibbert K. Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection. Retrovirology. 2015;12:66 pubmed publisher
Clouthier D, Zhou A, Wortzman M, Luft O, Levy G, Watts T. GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection. PLoS Pathog. 2015;11:e1004517 pubmed publisher
Baeyens A, Saadoun D, Billiard F, Rouers A, Grégoire S, Zaragoza B, et al. Effector T cells boost regulatory T cell expansion by IL-2, TNF, OX40, and plasmacytoid dendritic cells depending on the immune context. J Immunol. 2015;194:999-1010 pubmed publisher
McKinstry K, Strutt T, Bautista B, Zhang W, Kuang Y, Cooper A, et al. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014;5:5377 pubmed publisher
Mizui M, Koga T, Lieberman L, Beltrán J, Yoshida N, Johnson M, et al. IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells. J Immunol. 2014;193:2168-77 pubmed publisher
Srivastava S, Koch M, Pepper M, Campbell D. Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J Exp Med. 2014;211:961-74 pubmed publisher
Smigiel K, Richards E, Srivastava S, Thomas K, Dudda J, Klonowski K, et al. CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. J Exp Med. 2014;211:121-36 pubmed publisher
Gasteiger G, Hemmers S, Bos P, Sun J, Rudensky A. IL-2-dependent adaptive control of NK cell homeostasis. J Exp Med. 2013;210:1179-87 pubmed publisher
Gratz I, Truong H, Yang S, Maurano M, Lee K, Abbas A, et al. Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues. J Immunol. 2013;190:4483-7 pubmed publisher
Smith C, Martinez M, Peet J, Khanna R. Differential outcome of IL-2/anti-IL-2 complex therapy on effector and memory CD8+ T cells following vaccination with an adenoviral vector encoding EBV epitopes. J Immunol. 2011;186:5784-90 pubmed publisher
Hamilton S, Schenkel J, Akue A, Jameson S. IL-2 complex treatment can protect naive mice from bacterial and viral infection. J Immunol. 2010;185:6584-90 pubmed publisher
product information
Catalog Number :
BE0043-1-25MG
Product Name :
InVivoMAb anti-mouse IL-2
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$2,009.00
Academic Price :
1,306.00 USD
Clone Name :
JES6-1A12
Isotype :
S4B6-1
Immunogen :
Recombinant mouse IL-2
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo IL-2 neutralization, in vivo IL-2 receptor stimulation (as a complex with IL-2)
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA