product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse IL-2
catalog :
BE0042-25MG
quantity :
25 mg
price :
1,306.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
JES6-5H4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 8
Reference
Villegas Mendez A, Shaw T, Inkson C, Strangward P, de Souza J, Couper K. Parasite-Specific CD4+ IFN-γ+ IL-10+ T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection. Infect Immun. 2016;84:34-46 pubmed publisher
Srivastava S, Koch M, Pepper M, Campbell D. Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J Exp Med. 2014;211:961-74 pubmed publisher
Gasteiger G, Hemmers S, Bos P, Sun J, Rudensky A. IL-2-dependent adaptive control of NK cell homeostasis. J Exp Med. 2013;210:1179-87 pubmed publisher
Villegas Mendez A, de Souza J, Lavelle S, Gwyer Findlay E, Shaw T, Van Rooijen N, et al. IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog. 2013;9:e1003293 pubmed publisher
Gwyer Findlay E, Villegas Mendez A, de Souza J, Inkson C, Shaw T, Saris C, et al. IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection. J Immunol. 2013;190:4553-61 pubmed publisher
Cho H, Reyes Vargas E, Delgado J, Celis E. A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy. Cancer Res. 2012;72:1986-95 pubmed publisher
Weber K, Hildner K, Murphy K, Allen P. Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization. J Immunol. 2010;185:2836-46 pubmed publisher
Carlson M, West M, COGHILL J, Panoskaltsis Mortari A, Blazar B, Serody J. In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations. Blood. 2009;113:1365-74 pubmed publisher
product information
Catalog Number :
BE0042-25MG
Product Name :
InVivoMAb anti-mouse IL-2
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$2,009.00
Academic Price :
1,306.00 USD
Clone Name :
JES6-5H4
Isotype :
JES6-5H4
Immunogen :
Recombinant mouse IL-2
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo IL-2 neutralization, in vitro IL-2 neutralization, in vivo IL-2 receptor stimulation (as a complex with IL-2), ELISPOT, Flow cytometry
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA