product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CTLA-4 (CD152)
catalog :
BE0032-25MG
quantity :
25 mg
price :
1,306.00 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
UC10-4F10-11
reactivity :
mouse
application :
western blot, flow cytometry
more info or order :
citations: 16
Reference
Peterson M, Murphy S, Lainson J, Zhang J, Shen L, Diehnelt C, et al. Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model. BMC Immunol. 2020;21:25 pubmed publisher
Triplett T, Garrison K, Marshall N, Donkor M, Blazeck J, Lamb C, et al. Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme. Nat Biotechnol. 2018;36:758-764 pubmed publisher
Xiang B, Baybutt T, Berman Booty L, Magee M, Waldman S, Alexeev V, et al. Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells. J Immunol. 2017;198:3507-3514 pubmed publisher
Holt M, Punkosdy G, Glass D, Shevach E. TCR Signaling and CD28/CTLA-4 Signaling Cooperatively Modulate T Regulatory Cell Homeostasis. J Immunol. 2017;198:1503-1511 pubmed publisher
Welten S, Redeker A, Franken K, Oduro J, Ossendorp F, Čičin Šain L, et al. The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion. elife. 2015;4: pubmed publisher
Makkouk A, Joshi V, Lemke C, Wongrakpanich A, Olivier A, Blackwell S, et al. Three steps to breaking immune tolerance to lymphoma: a microparticle approach. Cancer Immunol Res. 2015;3:389-98 pubmed publisher
Pletinckx K, Vaeth M, Schneider T, Beyersdorf N, Hünig T, Berberich Siebelt F, et al. Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4. Eur J Immunol. 2015;45:480-91 pubmed publisher
Zhu Y, Knolhoff B, Meyer M, Nywening T, West B, Luo J, et al. CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res. 2014;74:5057-69 pubmed publisher
Mittal D, Young A, Stannard K, Yong M, Teng M, Allard B, et al. Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor. Cancer Res. 2014;74:3652-8 pubmed publisher
Rabenstein H, Behrendt A, Ellwart J, Naumann R, Horsch M, Beckers J, et al. Differential kinetics of antigen dependency of CD4+ and CD8+ T cells. J Immunol. 2014;192:3507-17 pubmed publisher
Honda T, Egen J, Lämmermann T, Kastenmüller W, Torabi Parizi P, Germain R. Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues. Immunity. 2014;40:235-247 pubmed publisher
Allard B, Pommey S, Smyth M, Stagg J. Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs. Clin Cancer Res. 2013;19:5626-35 pubmed publisher
Hafalla J, Claser C, Couper K, Grau G, Renia L, de Souza J, et al. The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog. 2012;8:e1002504 pubmed publisher
Haque A, Best S, Amante F, Mustafah S, Desbarrieres L, de Labastida F, et al. CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo. PLoS Pathog. 2010;6:e1001221 pubmed publisher
Noval Rivas M, Weatherly K, Hazzan M, Vokaer B, Dremier S, Gaudray F, et al. Reviving function in CD4+ T cells adapted to persistent systemic antigen. J Immunol. 2009;183:4284-91 pubmed publisher
Rowe J, Johanns T, Ertelt J, Lai J, Way S. Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge. Immunology. 2009;128:e471-8 pubmed publisher
product information
Catalog Number :
BE0032-25MG
Product Name :
InVivoMAb anti-mouse CTLA-4 (CD152)
Host :
Armenian Hamster
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$2,009.00
Academic Price :
1,306.00 USD
Clone Name :
UC10-4F10-11
Isotype :
UC10-4F10-11
Immunogen :
Mouse CTLA-4 IgG2a fusion protein
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Flow cytometry, Western blot
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA